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The map label for this gene is nudL [H]

Identifier: 55981916

GI number: 55981916

Start: 1824153

End: 1824620

Strand: Direct

Name: nudL [H]

Synonym: TTHA1947

Alternate gene names: 55981916

Gene position: 1824153-1824620 (Clockwise)

Preceding gene: 55981915

Following gene: 55981917

Centisome position: 98.62

GC content: 67.95

Gene sequence:

>468_bases
GTGGCCGTGCCCCTTCTGGGGGAGCACCTCCTCTTCACCTTAAGGAGCCCCCGCCTCCCCACCCACGCCGGCCAGGTGAG
CTTCCCCGGGGGGGTGGTGGAGCCCGGGGAAGGGGTGGTGGAGGCGGCCCTGAGGGAGGCCGAGGAGGAGGTGGGGCTAA
AGGGGGTGGAGCCTTTGGGCTTCCTCTCCCCCACCTACTCCCCCCAGGGCTTCCTGGTCCAGCCCGTGGTGGTCTTCCGG
GAAGACCTGCCCCCCCTGAAGCCCAACCCCGAGGAGGTGGCGGAAATCCTCCTCGCCCCCCTGGGGGAGCTTCTAGAAGT
GGAGCCCTGGAGCGAGGTGCGATTAGGCCGCATTGTCTGGCACTTCCCCTGGCGGGGGGTGGACATCTGGGGGGTGACGG
GGAATATCCTGAAGGCGTTCCTGGAGGTGTGGCGTGAAGGGAAAAGCCCCCCTCACGAGCTTCTCTAA

Upstream 100 bases:

>100_bases
TCGCCGCCAAGGGGATGGACCCCGAGAGCGCCTTAAGGAAGCGCTCCCTCAAAGCCTGCCGGCAGGGCTAGAGCCCCCGC
CCGGCTTCCGCCTGGCGGCG

Downstream 100 bases:

>100_bases
GGGGGCTTCTGTAGTCCAATGAGGGGCCGGAGGTCTATCCCCAAAGGGGTGGCCTCCAAAGCTCAGGGTACTTCATAGGA
ACCGCTCACGCCGGCCTCTT

Product: MutT/nudix family protein

Products: AMP; D-Ribose 5- Phosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MAVPLLGEHLLFTLRSPRLPTHAGQVSFPGGVVEPGEGVVEAALREAEEEVGLKGVEPLGFLSPTYSPQGFLVQPVVVFR
EDLPPLKPNPEEVAEILLAPLGELLEVEPWSEVRLGRIVWHFPWRGVDIWGVTGNILKAFLEVWREGKSPPHELL

Sequences:

>Translated_155_residues
MAVPLLGEHLLFTLRSPRLPTHAGQVSFPGGVVEPGEGVVEAALREAEEEVGLKGVEPLGFLSPTYSPQGFLVQPVVVFR
EDLPPLKPNPEEVAEILLAPLGELLEVEPWSEVRLGRIVWHFPWRGVDIWGVTGNILKAFLEVWREGKSPPHELL
>Mature_154_residues
AVPLLGEHLLFTLRSPRLPTHAGQVSFPGGVVEPGEGVVEAALREAEEEVGLKGVEPLGFLSPTYSPQGFLVQPVVVFRE
DLPPLKPNPEEVAEILLAPLGELLEVEPWSEVRLGRIVWHFPWRGVDIWGVTGNILKAFLEVWREGKSPPHELL

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=149, Percent_Identity=37.5838926174497, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI32469515, Length=91, Percent_Identity=49.4505494505495, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17536993, Length=122, Percent_Identity=35.2459016393443, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17105; Mature: 16974

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPLLGEHLLFTLRSPRLPTHAGQVSFPGGVVEPGEGVVEAALREAEEEVGLKGVEPLG
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
FLSPTYSPQGFLVQPVVVFREDLPPLKPNPEEVAEILLAPLGELLEVEPWSEVRLGRIVW
CCCCCCCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCEEEE
HFPWRGVDIWGVTGNILKAFLEVWREGKSPPHELL
ECCCCCEEEECCCHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
AVPLLGEHLLFTLRSPRLPTHAGQVSFPGGVVEPGEGVVEAALREAEEEVGLKGVEPLG
CCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
FLSPTYSPQGFLVQPVVVFREDLPPLKPNPEEVAEILLAPLGELLEVEPWSEVRLGRIVW
CCCCCCCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCEEEE
HFPWRGVDIWGVTGNILKAFLEVWREGKSPPHELL
ECCCCCEEEECCCHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP-Ribose; H2O [C]

Specific reaction: ADP-Ribose + H2O = AMP + D-Ribose 5- Phosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]