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The map label for this gene is hacB [H]

Identifier: 55981879

GI number: 55981879

Start: 1793163

End: 1793654

Strand: Reverse

Name: hacB [H]

Synonym: TTHA1910

Alternate gene names: 55981879

Gene position: 1793654-1793163 (Counterclockwise)

Preceding gene: 55981880

Following gene: 55981878

Centisome position: 96.97

GC content: 65.65

Gene sequence:

>492_bases
ATGCCTAGGGTCTGGAAGTTCGGCGACCAGATCAACACCGACGACATCCTTCCCGGAAAGTACGCCCCCTTCATGGTGGG
GGAGGACCGGTTTCACCTCTACGCCTTCGCCCACTTGAGGCCCGAGTTCGCCAAGGAGGTGCGCCCCGGGGACATCCTCG
TCTTCGGGCGGAACGCGGGGCTCGGCTCTAGCCGCGAGTACGCCCCCGAGGCCCTGAAGCGCCTCGGCATCCGGGCCATC
ATCGCCAAAAGCTACGCCCGCATCTTCTTCCGCAACCTGGTGAACCTGGGGATCGTCCCCTTTGAGTCGGAGGAGGTGGT
GGATGCGCTAAAAGACGGCGACGAGGTGGAGTTGGACCTGGAAAGCGGGGTGCTCACCCGGGGGGAGGAGCGCTTCCTCC
TCCGTCCCCCGCCCCCCTTCCTCCTGGAGGCGCTCAAGGAGGGCTCCCTCCTGGACTACTACAAGAAGCACGGGCGCTTC
CCGGGGGAGTAG

Upstream 100 bases:

>100_bases
CCGGACGCCGAGATCTACCTGGCGAGCCCCCGCGTGGCCGCGGCGAGCGCCGTGGCGGGCTACCTCACCACCCCAGAGGA
GCTGGAAGAGGAGGAGGTCC

Downstream 100 bases:

>100_bases
ACTCTAGTCATGGAGGACCTAGAGATCGTCTGTCCGGTGTGCGGCGAGGCCAGCCTGGTGCTGGCGGAGGACCTCGAGGA
CCTCGAGGTCGGGGACGTGC

Product: homoaconitate hydratase small subunit

Products: NA

Alternate protein names: HACN; Homoaconitate hydratase [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MPRVWKFGDQINTDDILPGKYAPFMVGEDRFHLYAFAHLRPEFAKEVRPGDILVFGRNAGLGSSREYAPEALKRLGIRAI
IAKSYARIFFRNLVNLGIVPFESEEVVDALKDGDEVELDLESGVLTRGEERFLLRPPPPFLLEALKEGSLLDYYKKHGRF
PGE

Sequences:

>Translated_163_residues
MPRVWKFGDQINTDDILPGKYAPFMVGEDRFHLYAFAHLRPEFAKEVRPGDILVFGRNAGLGSSREYAPEALKRLGIRAI
IAKSYARIFFRNLVNLGIVPFESEEVVDALKDGDEVELDLESGVLTRGEERFLLRPPPPFLLEALKEGSLLDYYKKHGRF
PGE
>Mature_162_residues
PRVWKFGDQINTDDILPGKYAPFMVGEDRFHLYAFAHLRPEFAKEVRPGDILVFGRNAGLGSSREYAPEALKRLGIRAII
AKSYARIFFRNLVNLGIVPFESEEVVDALKDGDEVELDLESGVLTRGEERFLLRPPPPFLLEALKEGSLLDYYKKHGRFP
GE

Specific function: Catalyzes the reversible hydration of cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate) to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Can catalyze neither the dehydration of (R)-homocitrate ((2R)-2-hydroxybutane-1,2,4- tricarboxy

COG id: COG0066

COG function: function code E; 3-isopropylmalate dehydratase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leuD family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320440, Length=106, Percent_Identity=37.7358490566038, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012305
- InterPro:   IPR015937
- InterPro:   IPR015928
- InterPro:   IPR000573
- InterPro:   IPR011827 [H]

Pfam domain/function: PF00694 Aconitase_C [H]

EC number: =4.2.1.36 [H]

Molecular weight: Translated: 18523; Mature: 18392

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVWKFGDQINTDDILPGKYAPFMVGEDRFHLYAFAHLRPEFAKEVRPGDILVFGRNAG
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCHHHHHHCCCCCEEEEECCCC
LGSSREYAPEALKRLGIRAIIAKSYARIFFRNLVNLGIVPFESEEVVDALKDGDEVELDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEC
ESGVLTRGEERFLLRPPPPFLLEALKEGSLLDYYKKHGRFPGE
CCCCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRVWKFGDQINTDDILPGKYAPFMVGEDRFHLYAFAHLRPEFAKEVRPGDILVFGRNAG
CCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCHHHHHHCCCCCEEEEECCCC
LGSSREYAPEALKRLGIRAIIAKSYARIFFRNLVNLGIVPFESEEVVDALKDGDEVELDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEC
ESGVLTRGEERFLLRPPPPFLLEALKEGSLLDYYKKHGRFPGE
CCCCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10074061 [H]