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The map label for this gene is argC [H]

Identifier: 55981873

GI number: 55981873

Start: 1790047

End: 1791084

Strand: Reverse

Name: argC [H]

Synonym: TTHA1904

Alternate gene names: 55981873

Gene position: 1791084-1790047 (Counterclockwise)

Preceding gene: 55981874

Following gene: 55981872

Centisome position: 96.83

GC content: 68.88

Gene sequence:

>1038_bases
ATGACCGGTAAGAAAACCCTTTCCATCGTGGGGGCCTCGGGGTACGCCGGGGGAGAGTTCCTGAGGCTCGCCCTTTCCCA
CCCCTATCTGGAAGTGAAGCAGGTGACCTCGAGGCGCTTCGCGGGCGAGCCCGTCCACTTCGTCCACCCCAACCTCCGAG
GACGCACGAACCTCAAGTTCGTCCCCCCGGAGAAGCTGGAGCCCGCGGACATCCTGGTCCTGGCCCTGCCCCACGGGGTC
TTCGCCCGGGAGTTTGACCGCTACAGCGCCCTGGCCCCCGTCCTCGTGGACCTCTCCGCGGACTTCCGCCTGAAGGACCC
GGAGCTTTACCGCAGGTACTACGGGGAGCACCCGAGGCCAGACCTCCTTGGCCGCTTCGTCTACGCCGTGCCCGAGCTCT
ACCGGGAGGCCCTGAAGGGGGCGGACTGGATCGCCGGGGCCGGGTGCAACGCCACGGCCACCCTTCTCGGCCTCTACCCC
CTCCTCAAGGCCGGGGTCCTGAAGCCCACCCCCATCTTCGTCACCCTCCTCATCTCCACCTCGGCAGGGGGGGCCGAGGC
GAGCCCGGCGAGCCACCACCCCGAAAGGGCCGGGTCCATCCGGGTCTACAAGCCCACGGGCCACCGCCACACCGCCGAGG
TGGTGGAAAACCTCCCCGGCCGCCCCGAGGTCCACCTCACCGCCATCGCCACCGACCGGGTGCGGGGGATCCTCATGACC
GCCCAGTGCTTCGTCCAGGACGGCTGGAGCGAAAGGGACGTCTGGCAGGCCTACCGGGAGGCCTACGCCGGGGAGCCCTT
CATCCGCCTCGTCAAGCAGAAGAAGGGGGTCCACCGCTACCCCGACCCCCGTTTCGTCCAGGGCACCAACTACGCCGACA
TCGGCTTTGAGCTGGAGGAGGACACGGGGAGGCTCGTGGTCATGACGGCCATTGACAACCTGGTGAAGGGCACCGCGGGC
CACGCCCTCCAGGCCCTAAACGTCCGCATGGGCTGGCCCGAGACCCTGGGCCTGGACTTCCCGGGGCTTCACCCCTAA

Upstream 100 bases:

>100_bases
GTGCAGGCCCGCTACCCTGACCTGGAAGTTCTGCCGGAAGAGGCCCGGGAAGCCCTTTCCCTGGCCCAAGTCCTGGTGGC
GGAGCTTAGGAGGTGGCTCC

Downstream 100 bases:

>100_bases
GGCCAACCGCTTGGCAGGGGAGGTGAGCTTGTGATCGTGGTCAAGGTGGGAGGCGCCGAGGGGATCAACTACGAGGCCGT
GGCCAAGGACGCCGCCTCCT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTGKKTLSIVGASGYAGGEFLRLALSHPYLEVKQVTSRRFAGEPVHFVHPNLRGRTNLKFVPPEKLEPADILVLALPHGV
FAREFDRYSALAPVLVDLSADFRLKDPELYRRYYGEHPRPDLLGRFVYAVPELYREALKGADWIAGAGCNATATLLGLYP
LLKAGVLKPTPIFVTLLISTSAGGAEASPASHHPERAGSIRVYKPTGHRHTAEVVENLPGRPEVHLTAIATDRVRGILMT
AQCFVQDGWSERDVWQAYREAYAGEPFIRLVKQKKGVHRYPDPRFVQGTNYADIGFELEEDTGRLVVMTAIDNLVKGTAG
HALQALNVRMGWPETLGLDFPGLHP

Sequences:

>Translated_345_residues
MTGKKTLSIVGASGYAGGEFLRLALSHPYLEVKQVTSRRFAGEPVHFVHPNLRGRTNLKFVPPEKLEPADILVLALPHGV
FAREFDRYSALAPVLVDLSADFRLKDPELYRRYYGEHPRPDLLGRFVYAVPELYREALKGADWIAGAGCNATATLLGLYP
LLKAGVLKPTPIFVTLLISTSAGGAEASPASHHPERAGSIRVYKPTGHRHTAEVVENLPGRPEVHLTAIATDRVRGILMT
AQCFVQDGWSERDVWQAYREAYAGEPFIRLVKQKKGVHRYPDPRFVQGTNYADIGFELEEDTGRLVVMTAIDNLVKGTAG
HALQALNVRMGWPETLGLDFPGLHP
>Mature_344_residues
TGKKTLSIVGASGYAGGEFLRLALSHPYLEVKQVTSRRFAGEPVHFVHPNLRGRTNLKFVPPEKLEPADILVLALPHGVF
AREFDRYSALAPVLVDLSADFRLKDPELYRRYYGEHPRPDLLGRFVYAVPELYREALKGADWIAGAGCNATATLLGLYPL
LKAGVLKPTPIFVTLLISTSAGGAEASPASHHPERAGSIRVYKPTGHRHTAEVVENLPGRPEVHLTAIATDRVRGILMTA
QCFVQDGWSERDVWQAYREAYAGEPFIRLVKQKKGVHRYPDPRFVQGTNYADIGFELEEDTGRLVVMTAIDNLVKGTAGH
ALQALNVRMGWPETLGLDFPGLHP

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=340, Percent_Identity=32.9411764705882, Blast_Score=141, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6320913, Length=344, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 38091; Mature: 37960

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKKTLSIVGASGYAGGEFLRLALSHPYLEVKQVTSRRFAGEPVHFVHPNLRGRTNLKF
CCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCEEE
VPPEKLEPADILVLALPHGVFAREFDRYSALAPVLVDLSADFRLKDPELYRRYYGEHPRP
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCEECCHHHHHHHCCCCCCH
DLLGRFVYAVPELYREALKGADWIAGAGCNATATLLGLYPLLKAGVLKPTPIFVTLLIST
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
SAGGAEASPASHHPERAGSIRVYKPTGHRHTAEVVENLPGRPEVHLTAIATDRVRGILMT
CCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHH
AQCFVQDGWSERDVWQAYREAYAGEPFIRLVKQKKGVHRYPDPRFVQGTNYADIGFELEE
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEECCCCEEECCEEEEC
DTGRLVVMTAIDNLVKGTAGHALQALNVRMGWPETLGLDFPGLHP
CCCCEEEEEHHHHHHHCCCCHHEEEEEEECCCCHHCCCCCCCCCC
>Mature Secondary Structure 
TGKKTLSIVGASGYAGGEFLRLALSHPYLEVKQVTSRRFAGEPVHFVHPNLRGRTNLKF
CCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCEEE
VPPEKLEPADILVLALPHGVFAREFDRYSALAPVLVDLSADFRLKDPELYRRYYGEHPRP
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCEECCHHHHHHHCCCCCCH
DLLGRFVYAVPELYREALKGADWIAGAGCNATATLLGLYPLLKAGVLKPTPIFVTLLIST
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
SAGGAEASPASHHPERAGSIRVYKPTGHRHTAEVVENLPGRPEVHLTAIATDRVRGILMT
CCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHH
AQCFVQDGWSERDVWQAYREAYAGEPFIRLVKQKKGVHRYPDPRFVQGTNYADIGFELEE
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEECCCCEEECCEEEEC
DTGRLVVMTAIDNLVKGTAGHALQALNVRMGWPETLGLDFPGLHP
CCCCEEEEEHHHHHHHCCCCHHEEEEEEECCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10074061; 9418242 [H]