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The map label for this gene is moaC [H]

Identifier: 55981758

GI number: 55981758

Start: 1673616

End: 1674089

Strand: Reverse

Name: moaC [H]

Synonym: TTHA1789

Alternate gene names: 55981758

Gene position: 1674089-1673616 (Counterclockwise)

Preceding gene: 55981759

Following gene: 55981757

Centisome position: 90.5

GC content: 67.93

Gene sequence:

>474_bases
ATGGACCTCACCCACTTCCAGGACGGCCGGCCCCGGATGGTGGACGTGACGGAGAAACCCGAAACCTTCCGCACCGCCAC
CGCCGAGGCCTTCGTGGAGCTCACCGAGGAGGCCCTTTCCGCCCTGGAGAAGGGCGGGGTGGGGAAGGGGGACCCCCTCG
TCGTGGCCCAGCTTGCGGGGATCCTCGCCGCCAAGAAGACGGCGGACCTCATTCCCCTCTGCCACCCCCTCCCCCTTACC
GGGGTGGAGGTCAGGGTGGAGCTCCTTAAGGCGGAAAAGCGGGTGCGCATTGAGGCCACGGTGAAGACCAAGGCGGAGAC
GGGGGTGGAGATGGAGGCCATGACCGCCTGCGCCGTCGCCGCCCTCACCGTCTACGACATGCTCAAGGCCGCTTCCAAGG
GCCTCGTCATCTCCCAGGTGCGCCTCCTCCACAAGGCAGGGGGAAAGAGCGGGGAGTGGCGTAGGGAGCAGTAG

Upstream 100 bases:

>100_bases
CCTGAAGGGGGTGGAGAAGGGGTTTGACCTGGTCAAGTACCGCCTCTTCGGCCGGAGGCTTGGCCTGAGGCTCCCCACCC
CGAGGGGATAGACTCAGGGC

Downstream 100 bases:

>100_bases
GCCTACCCCGGGGGTGTACGCTGAGTACATGCGGGTCGCCATTGCCTTAGCCAAGGACGACGCCACCCGGGTCTACCCCG
GCCCCTTCGGCCACGCTCCC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDLTHFQDGRPRMVDVTEKPETFRTATAEAFVELTEEALSALEKGGVGKGDPLVVAQLAGILAAKKTADLIPLCHPLPLT
GVEVRVELLKAEKRVRIEATVKTKAETGVEMEAMTACAVAALTVYDMLKAASKGLVISQVRLLHKAGGKSGEWRREQ

Sequences:

>Translated_157_residues
MDLTHFQDGRPRMVDVTEKPETFRTATAEAFVELTEEALSALEKGGVGKGDPLVVAQLAGILAAKKTADLIPLCHPLPLT
GVEVRVELLKAEKRVRIEATVKTKAETGVEMEAMTACAVAALTVYDMLKAASKGLVISQVRLLHKAGGKSGEWRREQ
>Mature_157_residues
MDLTHFQDGRPRMVDVTEKPETFRTATAEAFVELTEEALSALEKGGVGKGDPLVVAQLAGILAAKKTADLIPLCHPLPLT
GVEVRVELLKAEKRVRIEATVKTKAETGVEMEAMTACAVAALTVYDMLKAASKGLVISQVRLLHKAGGKSGEWRREQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=53.5483870967742, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.2818791946309, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=53.8461538461538, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=55.1724137931034, Blast_Score=153, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16922; Mature: 16922

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTHFQDGRPRMVDVTEKPETFRTATAEAFVELTEEALSALEKGGVGKGDPLVVAQLAG
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ILAAKKTADLIPLCHPLPLTGVEVRVELLKAEKRVRIEATVKTKAETGVEMEAMTACAVA
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEHHHCCCHHHHHHHHHHH
ALTVYDMLKAASKGLVISQVRLLHKAGGKSGEWRREQ
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDLTHFQDGRPRMVDVTEKPETFRTATAEAFVELTEEALSALEKGGVGKGDPLVVAQLAG
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ILAAKKTADLIPLCHPLPLTGVEVRVELLKAEKRVRIEATVKTKAETGVEMEAMTACAVA
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEHHHCCCHHHHHHHHHHH
ALTVYDMLKAASKGLVISQVRLLHKAGGKSGEWRREQ
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA