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The map label for this gene is cpg2 [H]

Identifier: 55981667

GI number: 55981667

Start: 1595519

End: 1596643

Strand: Direct

Name: cpg2 [H]

Synonym: TTHA1698

Alternate gene names: 55981667

Gene position: 1595519-1596643 (Clockwise)

Preceding gene: 55981631

Following gene: 55981668

Centisome position: 86.26

GC content: 72.0

Gene sequence:

>1125_bases
ATGGGGGCCATGGAAAGCCTTCGCTGGATGGAAGCCCGCCTCCCCGAGATCCTCAAGGACCTGGAGGCCTTCGTCCGCCG
GGAGTCCCCCTCGGGGGACCTGGAGGGCCTGGAGGCCGCCGCCCGCTTCCTGGAGGAGGCCTTCGGGCCCCTCGAGGGCC
GCCTCTCCCGCAAGGACACCCCCGCGGGCCCCGTCCTCCTCCTCAAGCGGGAGGGCGAGGGCGCCCCCGTGCTCCTCCTC
TGCCACTACGACACCGTCCACCCCAAGGGGAGCTTCCCCGAGCCCTTCCGCCTGGAGCGGGAGAAGGCCATTGGTCCCGG
GGTCTACGACATGAAGGGGGGGATCATCGCCCTCCTCTACGCCCTGCGCTACGCCGAGGCCACGGGGCGGAGGCTTCCCG
CCCTCGAGGTCCTCTTCACCCCCGACGAGGAGGTGGGCTCCCCGGAAAGCCGCCCCCTCATTGAGGCCGCCGCCAAGAAG
GCCCGGGCGGTGCTGGTCCTGGAACCCCCCACCGCGGAAGGCCACCTGAAGGTGGCCCGCAAGGGGGTAGGGCTTTACCG
GCTTAGGGCCATCGGCAAGGCCGCCCACCAGGGGGTGGAGCCGGAGAAAGGGGTGAACGCCATCCTGGAGCTCGCCCACC
AGGTCCTCAAGGTGGCGGCCCTGGAGGACCGGGAGAAGGGGACCACCCTGGGGCCGAACCGCATCCGGGGCGGCACGGCC
ACCAACGTGGTGGCCGAGGAGGCGGAGGTGGAGATTGACCTCAGGGCCTGGACCCTGGAGGAGGTGCAGCGGGTGGAGGA
AGGGCTTAAGGCCCTAAAGCCCGTCCTGCCGGGGGCCAGGCTCGTGCTCTCGGGTGGCCTCAACCGCCCCCCCATGGAGC
CCACGGAGGCAAGCCTCGCCCTCTTCGCCAAGGCCCGGGCCATCGGGGAGGCCCTTGGCCTGAGGCTCGAGCCCGGCCGG
GTGGGCGGGGGGTCGGACGGGAACTTCACCGCCGCCCTGGGAGTGCCCACCCTGGACGGCCTGGGGCTTTTCGGGGGCAA
CGCCCACCAGAAGACGGAGTACGTGGTGGTGCCGGAGATCCCCCGCCGCACCGCCCTCCTCGCCGAGCTTCTCGCCGCCC
TATGA

Upstream 100 bases:

>100_bases
ACCCTCAGGGCCAGGGGCTGGCCCTGAGAGCCCTCAACTGCCCTAGTGTACAGGCAAAACCCTTCCTTGGCAATACCTTC
CAAGGCGAGGCCCTGCCATA

Downstream 100 bases:

>100_bases
GCCTCTCCCCCTCCGCCCGACGGGTCCAAGGGGCCCTCGAGACCCGGGGCTTCGGCCACCTGAAGGTGGTGGAGCTTCCC
GCCTCCACCCGCACCGCCAA

Product: carboxypeptidase G2

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MGAMESLRWMEARLPEILKDLEAFVRRESPSGDLEGLEAAARFLEEAFGPLEGRLSRKDTPAGPVLLLKREGEGAPVLLL
CHYDTVHPKGSFPEPFRLEREKAIGPGVYDMKGGIIALLYALRYAEATGRRLPALEVLFTPDEEVGSPESRPLIEAAAKK
ARAVLVLEPPTAEGHLKVARKGVGLYRLRAIGKAAHQGVEPEKGVNAILELAHQVLKVAALEDREKGTTLGPNRIRGGTA
TNVVAEEAEVEIDLRAWTLEEVQRVEEGLKALKPVLPGARLVLSGGLNRPPMEPTEASLALFAKARAIGEALGLRLEPGR
VGGGSDGNFTAALGVPTLDGLGLFGGNAHQKTEYVVVPEIPRRTALLAELLAAL

Sequences:

>Translated_374_residues
MGAMESLRWMEARLPEILKDLEAFVRRESPSGDLEGLEAAARFLEEAFGPLEGRLSRKDTPAGPVLLLKREGEGAPVLLL
CHYDTVHPKGSFPEPFRLEREKAIGPGVYDMKGGIIALLYALRYAEATGRRLPALEVLFTPDEEVGSPESRPLIEAAAKK
ARAVLVLEPPTAEGHLKVARKGVGLYRLRAIGKAAHQGVEPEKGVNAILELAHQVLKVAALEDREKGTTLGPNRIRGGTA
TNVVAEEAEVEIDLRAWTLEEVQRVEEGLKALKPVLPGARLVLSGGLNRPPMEPTEASLALFAKARAIGEALGLRLEPGR
VGGGSDGNFTAALGVPTLDGLGLFGGNAHQKTEYVVVPEIPRRTALLAELLAAL
>Mature_373_residues
GAMESLRWMEARLPEILKDLEAFVRRESPSGDLEGLEAAARFLEEAFGPLEGRLSRKDTPAGPVLLLKREGEGAPVLLLC
HYDTVHPKGSFPEPFRLEREKAIGPGVYDMKGGIIALLYALRYAEATGRRLPALEVLFTPDEEVGSPESRPLIEAAAKKA
RAVLVLEPPTAEGHLKVARKGVGLYRLRAIGKAAHQGVEPEKGVNAILELAHQVLKVAALEDREKGTTLGPNRIRGGTAT
NVVAEEAEVEIDLRAWTLEEVQRVEEGLKALKPVLPGARLVLSGGLNRPPMEPTEASLALFAKARAIGEALGLRLEPGRV
GGGSDGNFTAALGVPTLDGLGLFGGNAHQKTEYVVVPEIPRRTALLAELLAAL

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=269, Percent_Identity=29.368029739777, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 40075; Mature: 39944

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAMESLRWMEARLPEILKDLEAFVRRESPSGDLEGLEAAARFLEEAFGPLEGRLSRKDT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PAGPVLLLKREGEGAPVLLLCHYDTVHPKGSFPEPFRLEREKAIGPGVYDMKGGIIALLY
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCHHCCHHHHHHH
ALRYAEATGRRLPALEVLFTPDEEVGSPESRPLIEAAAKKARAVLVLEPPTAEGHLKVAR
HHHHHHHCCCCCCEEEEEECCCHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHH
KGVGLYRLRAIGKAAHQGVEPEKGVNAILELAHQVLKVAALEDREKGTTLGPNRIRGGTA
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
TNVVAEEAEVEIDLRAWTLEEVQRVEEGLKALKPVLPGARLVLSGGLNRPPMEPTEASLA
HHHEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHH
LFAKARAIGEALGLRLEPGRVGGGSDGNFTAALGVPTLDGLGLFGGNAHQKTEYVVVPEI
HHHHHHHHHHHHCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCC
PRRTALLAELLAAL
CHHHHHHHHHHHHC
>Mature Secondary Structure 
GAMESLRWMEARLPEILKDLEAFVRRESPSGDLEGLEAAARFLEEAFGPLEGRLSRKDT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PAGPVLLLKREGEGAPVLLLCHYDTVHPKGSFPEPFRLEREKAIGPGVYDMKGGIIALLY
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCHHCCHHHHHHH
ALRYAEATGRRLPALEVLFTPDEEVGSPESRPLIEAAAKKARAVLVLEPPTAEGHLKVAR
HHHHHHHCCCCCCEEEEEECCCHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHH
KGVGLYRLRAIGKAAHQGVEPEKGVNAILELAHQVLKVAALEDREKGTTLGPNRIRGGTA
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
TNVVAEEAEVEIDLRAWTLEEVQRVEEGLKALKPVLPGARLVLSGGLNRPPMEPTEASLA
HHHEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHH
LFAKARAIGEALGLRLEPGRVGGGSDGNFTAALGVPTLDGLGLFGGNAHQKTEYVVVPEI
HHHHHHHHHHHHCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCC
PRRTALLAELLAAL
CHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]