Click here to switch to the map view.

The map label for this gene is ntcA [H]

Identifier: 55981536

GI number: 55981536

Start: 1490633

End: 1491256

Strand: Reverse

Name: ntcA [H]

Synonym: TTHA1567

Alternate gene names: 55981536

Gene position: 1491256-1490633 (Counterclockwise)

Preceding gene: 55981537

Following gene: 55981535

Centisome position: 80.62

GC content: 72.28

Gene sequence:

>624_bases
ATGCTCCAAGGACTGAGCCTCGAGGCCCGCCAAGAGGCCCTCAAGGTCTTCCGTCCTTTGCGCTTGAGGCGGGGGGCGGT
CCTCTTCGCCCCCGGGGACCCCGTGGACGGGGTCTACCTGGTGCGCCAGGGCCTCGTCGGGCTCCACCGGCCGGGGCCGG
GCCTGGAGGAAGGGGTCTTGGACGTGGTGGGGCCGGGGGGGGTCTTTGGGGAGGAGGCCTTGGGGGGGGAGGCGAGGCGG
CGCGCCGGGGCCGAGGCCCTCACCTACGCCGAGCTCTACTTCGCCCCCCGGGAGGGCTTGGCCGCCCTAAGGGCGCGCTT
CGCCGAGGTAGAGGCCTTTTTCCTTCAGGCCCTTTACGGGCGGCTCTGCTCCTTGGAGGAGCGGCTTTGGGAGGCGCGCC
ACCTCTCCGTGGCCCAGCGCCTGGCCCGCCTCCTCCTCCGGATGGGGGAGGACGGGGTCGCCCCCTTCTCCCACCAGGAC
CTGGCCCGGATGGTGGGGGCCTCCCGGGAGACGGTCACCAAGCTCCTCGGGGAGTGGGCGCTGAAAGGGTGGGTGGACCT
GGGCTACCGCAGGGTGGAGGTCCTGGAGCCCAAGGCCCTTGCCCGCCTTGCCGAGGAACTTTAG

Upstream 100 bases:

>100_bases
GGAGGAGGGGGAACGGGCCGTGGCCCGCCTCTTCGCCGAGGCCGAGGCCCGGGGGCTTGCCGCCCCCAGCCCCCGGCCCC
TTTTCGTGTAAACTCGGGCC

Downstream 100 bases:

>100_bases
GCTTTAAAGCATGGAAGCCGCCTGTCTGGTCCGCAGCCTGGGCCTGCCGCAGGGGGAGGAGGCCCTGAAGGCCCGCCTCC
GCCGCCCGGGCCACCCCCGG

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: DNA-binding protein VF1; Nitrogen-responsive regulatory protein [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLQGLSLEARQEALKVFRPLRLRRGAVLFAPGDPVDGVYLVRQGLVGLHRPGPGLEEGVLDVVGPGGVFGEEALGGEARR
RAGAEALTYAELYFAPREGLAALRARFAEVEAFFLQALYGRLCSLEERLWEARHLSVAQRLARLLLRMGEDGVAPFSHQD
LARMVGASRETVTKLLGEWALKGWVDLGYRRVEVLEPKALARLAEEL

Sequences:

>Translated_207_residues
MLQGLSLEARQEALKVFRPLRLRRGAVLFAPGDPVDGVYLVRQGLVGLHRPGPGLEEGVLDVVGPGGVFGEEALGGEARR
RAGAEALTYAELYFAPREGLAALRARFAEVEAFFLQALYGRLCSLEERLWEARHLSVAQRLARLLLRMGEDGVAPFSHQD
LARMVGASRETVTKLLGEWALKGWVDLGYRRVEVLEPKALARLAEEL
>Mature_207_residues
MLQGLSLEARQEALKVFRPLRLRRGAVLFAPGDPVDGVYLVRQGLVGLHRPGPGLEEGVLDVVGPGGVFGEEALGGEARR
RAGAEALTYAELYFAPREGLAALRARFAEVEAFFLQALYGRLCSLEERLWEARHLSVAQRLARLLLRMGEDGVAPFSHQD
LARMVGASRETVTKLLGEWALKGWVDLGYRRVEVLEPKALARLAEEL

Specific function: Has affinity for the xisA upstream region. Binds to a 66 bp region containing three repeats of the consensus recognition sequence 5'-ACATT-3' [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 22799; Mature: 22799

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00014 ER_TARGET ; PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQGLSLEARQEALKVFRPLRLRRGAVLFAPGDPVDGVYLVRQGLVGLHRPGPGLEEGVL
CCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHCCH
DVVGPGGVFGEEALGGEARRRAGAEALTYAELYFAPREGLAALRARFAEVEAFFLQALYG
HHCCCCCCCCCHHCCHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RLCSLEERLWEARHLSVAQRLARLLLRMGEDGVAPFSHQDLARMVGASRETVTKLLGEWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
LKGWVDLGYRRVEVLEPKALARLAEEL
HHHHHHHCHHHHHHCCHHHHHHHHHHC
>Mature Secondary Structure
MLQGLSLEARQEALKVFRPLRLRRGAVLFAPGDPVDGVYLVRQGLVGLHRPGPGLEEGVL
CCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHCCH
DVVGPGGVFGEEALGGEARRRAGAEALTYAELYFAPREGLAALRARFAEVEAFFLQALYG
HHCCCCCCCCCHHCCHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RLCSLEERLWEARHLSVAQRLARLLLRMGEDGVAPFSHQDLARMVGASRETVTKLLGEWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
LKGWVDLGYRRVEVLEPKALARLAEEL
HHHHHHHCHHHHHHCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11114927 [H]