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The map label for this gene is yngE [H]

Identifier: 55981526

GI number: 55981526

Start: 1481244

End: 1482905

Strand: Direct

Name: yngE [H]

Synonym: TTHA1557

Alternate gene names: 55981526

Gene position: 1481244-1482905 (Clockwise)

Preceding gene: 55981525

Following gene: 55981532

Centisome position: 80.08

GC content: 68.35

Gene sequence:

>1662_bases
ATGCTGGAAACCGCCCTGCGCCCGGAGGACCGGGAAAGCCCCACCTTTAAGGCCAACAAGGACGCCTGGGTGGCCCTGGT
GCGGGACTTCAGGGAAAGCCTGGAAAGGGTGCGCCAGGGAGGTGGCCCCAAGGCCGTGGAGCGGCAGCACAAGAAGGGCC
GCCTCACCGCCAGGGAGCGCATACAAAAGCTCATAGACCCCGGCACGGAGTTCTACGAGCTCATGGCCTTCGCCGGATGG
GGGATGTACGAGGAGTGGGGCGGGGCCCCGGCGGGGGGGGTGATCACGGGGATCGGCCGCATCGCGGGACGGGACTGGAT
GATCGTCGCCAACGACGCCACGGTGAAGGCCGGGGCCTTCTTCCCCATCACCGCCAAGAAGGTGATCCGGGCCCAGACCA
TCGCCCTGGAAAACCGCATCCCCACGGTCTACCTGGTGGACTCCGCCGGGGTGTTCCTCCCCCTCCAGGACGAGGTCTTC
CCCGACCAGGACGACTTTGGCCGCATCTTCTACCTGAACGCCCGCATGTCGGCCCTGGGGATCCCCCAGATCTCGGCCAT
CATGGGGAACTGCGTGGCCGGGGGGGCCTACCTCCCCGTGATGACGGACGTCCTCATCATGACGGAGGGAAGCGGCCTCT
ACCTCGCGGGCCCCGCCCTGGTGAAGGCGGCCATCGGCCAGGAGGTCACCTCCGAGGAGCTCGGGGGGGCGAGGATGCAC
TACGAGGTCTCGGGAACGGTGGACTTCTACGAGCCCACGGACGAGGCGGCCTTGGCGCGCATAAGGGAGCTCGCCGCCCT
CTACCCGCCCCCCCGCCTCGCCCCTTGGGCGGAAGGGCGCAAAGCGCCCAAGGAACCCCTCTACCCCATAGAGGACCTCT
ACGGCCTGGTCTCCCCCGACGGCTCCCGCCCCTACGACCTCCGGGAGGTGATCGCCCGGATCGTGGACGGCTCGGAGTTT
CTGGAGTACAAGGGGGGGTACGGGGAGACCCTGGTCACGGGCTTCGCCCGGATCGGGGGGTACCCCGTGGGCATTGTGGG
CAACCAGCGCCTCGTCCTCAAGAAGCGGGGGCGGATTGAGGTGGGCGGGGTCATCTACGCCGAGGCGGCGGACAAGGCGG
CCCGGTTCATCCTCGAGGTCAACCAGATGGGGATCCCCCTCCTCTTCCTCCAGGACGTGACGGGCTTCATGGTGGGGAAG
GAGTCGGAGCAGGCGGGGATCATCAGGCGGGGGGCGAAGCTGGTGAACGCCGTCTCCAACTCGGTGGTGCCCAAGATCAC
CCTGATCCTCGGGGGGTCCTTCGGGGCGGGGAACTACGCCCTCGCGGGCAAGGCCTACGCCCCCCGGTTCCTCTTCGCCT
GGCCCAGCGCCAAGTACGCCGTGATGGGCGGGGCCCAGGCGGCGAAGACCCTTCTGGAGCTTGAGGTGGAGAAGCTCAAG
CGGGAGGGGAAGGAGCCCTCGGACGAGGAGCTCAAGGAGCTCTACGAGCGCATCAAGGGCCGCTACGAGGAGACCCTGGA
CCCCCGCTACGCCGCCGCCAGGCTCTGGGTGGACGGGGTGATCTTCCCCCACGAGACCCGGAAGTGGCTCATCAAGGCCC
TCGAGGCCTGCGCCCTGAACCCGGAGCGGGAGCCTTTCCGCATCGGGGTCTTCCAGGTCTAG

Upstream 100 bases:

>100_bases
GGAGGCGAGGCGCCAGGCCCAGTCCCAGGCCAAAACGCCCTGCCCGCCCCGGGCCCCCACGCTTTTTCACGAAGAGGCAT
AAAAGCGTTATAATCGGGCC

Downstream 100 bases:

>100_bases
AGGAGGCCCTTCACCCCGTCCGCCACGTACTGCACGGCCAGGGCGGCGAGGAGGAGGCCCAGGACGCGGGTGACCACGTT
CACCCCCGTCCGCCCCAGGG

Product: propionyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MLETALRPEDRESPTFKANKDAWVALVRDFRESLERVRQGGGPKAVERQHKKGRLTARERIQKLIDPGTEFYELMAFAGW
GMYEEWGGAPAGGVITGIGRIAGRDWMIVANDATVKAGAFFPITAKKVIRAQTIALENRIPTVYLVDSAGVFLPLQDEVF
PDQDDFGRIFYLNARMSALGIPQISAIMGNCVAGGAYLPVMTDVLIMTEGSGLYLAGPALVKAAIGQEVTSEELGGARMH
YEVSGTVDFYEPTDEAALARIRELAALYPPPRLAPWAEGRKAPKEPLYPIEDLYGLVSPDGSRPYDLREVIARIVDGSEF
LEYKGGYGETLVTGFARIGGYPVGIVGNQRLVLKKRGRIEVGGVIYAEAADKAARFILEVNQMGIPLLFLQDVTGFMVGK
ESEQAGIIRRGAKLVNAVSNSVVPKITLILGGSFGAGNYALAGKAYAPRFLFAWPSAKYAVMGGAQAAKTLLELEVEKLK
REGKEPSDEELKELYERIKGRYEETLDPRYAAARLWVDGVIFPHETRKWLIKALEACALNPEREPFRIGVFQV

Sequences:

>Translated_553_residues
MLETALRPEDRESPTFKANKDAWVALVRDFRESLERVRQGGGPKAVERQHKKGRLTARERIQKLIDPGTEFYELMAFAGW
GMYEEWGGAPAGGVITGIGRIAGRDWMIVANDATVKAGAFFPITAKKVIRAQTIALENRIPTVYLVDSAGVFLPLQDEVF
PDQDDFGRIFYLNARMSALGIPQISAIMGNCVAGGAYLPVMTDVLIMTEGSGLYLAGPALVKAAIGQEVTSEELGGARMH
YEVSGTVDFYEPTDEAALARIRELAALYPPPRLAPWAEGRKAPKEPLYPIEDLYGLVSPDGSRPYDLREVIARIVDGSEF
LEYKGGYGETLVTGFARIGGYPVGIVGNQRLVLKKRGRIEVGGVIYAEAADKAARFILEVNQMGIPLLFLQDVTGFMVGK
ESEQAGIIRRGAKLVNAVSNSVVPKITLILGGSFGAGNYALAGKAYAPRFLFAWPSAKYAVMGGAQAAKTLLELEVEKLK
REGKEPSDEELKELYERIKGRYEETLDPRYAAARLWVDGVIFPHETRKWLIKALEACALNPEREPFRIGVFQV
>Mature_553_residues
MLETALRPEDRESPTFKANKDAWVALVRDFRESLERVRQGGGPKAVERQHKKGRLTARERIQKLIDPGTEFYELMAFAGW
GMYEEWGGAPAGGVITGIGRIAGRDWMIVANDATVKAGAFFPITAKKVIRAQTIALENRIPTVYLVDSAGVFLPLQDEVF
PDQDDFGRIFYLNARMSALGIPQISAIMGNCVAGGAYLPVMTDVLIMTEGSGLYLAGPALVKAAIGQEVTSEELGGARMH
YEVSGTVDFYEPTDEAALARIRELAALYPPPRLAPWAEGRKAPKEPLYPIEDLYGLVSPDGSRPYDLREVIARIVDGSEF
LEYKGGYGETLVTGFARIGGYPVGIVGNQRLVLKKRGRIEVGGVIYAEAADKAARFILEVNQMGIPLLFLQDVTGFMVGK
ESEQAGIIRRGAKLVNAVSNSVVPKITLILGGSFGAGNYALAGKAYAPRFLFAWPSAKYAVMGGAQAAKTLLELEVEKLK
REGKEPSDEELKELYERIKGRYEETLDPRYAAARLWVDGVIFPHETRKWLIKALEACALNPEREPFRIGVFQV

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=546, Percent_Identity=48.7179487179487, Blast_Score=481, Evalue=1e-136,
Organism=Homo sapiens, GI119943100, Length=516, Percent_Identity=33.5271317829457, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI295821216, Length=536, Percent_Identity=32.6492537313433, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI310133460, Length=139, Percent_Identity=48.2014388489209, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17552936, Length=551, Percent_Identity=47.3684210526316, Blast_Score=495, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI25147362, Length=553, Percent_Identity=33.996383363472, Blast_Score=251, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI25147359, Length=540, Percent_Identity=34.0740740740741, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71997163, Length=505, Percent_Identity=20.990099009901, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586065, Length=559, Percent_Identity=47.4060822898032, Blast_Score=506, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 60696; Mature: 60696

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETALRPEDRESPTFKANKDAWVALVRDFRESLERVRQGGGPKAVERQHKKGRLTARER
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHH
IQKLIDPGTEFYELMAFAGWGMYEEWGGAPAGGVITGIGRIAGRDWMIVANDATVKAGAF
HHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCEEECCEE
FPITAKKVIRAQTIALENRIPTVYLVDSAGVFLPLQDEVFPDQDDFGRIFYLNARMSALG
ECCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCHHHCC
IPQISAIMGNCVAGGAYLPVMTDVLIMTEGSGLYLAGPALVKAAIGQEVTSEELGGARMH
CCHHHHHHHHHHCCCCHHHHHHCEEEEECCCCEEEECHHHHHHHHCCHHHHHHCCCEEEE
YEVSGTVDFYEPTDEAALARIRELAALYPPPRLAPWAEGRKAPKEPLYPIEDLYGLVSPD
EEEECEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
GSRPYDLREVIARIVDGSEFLEYKGGYGETLVTGFARIGGYPVGIVGNQRLVLKKRGRIE
CCCCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCEEEEEECCCEE
VGGVIYAEAADKAARFILEVNQMGIPLLFLQDVTGFMVGKESEQAGIIRRGAKLVNAVSN
ECCEEEECHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SVVPKITLILGGSFGAGNYALAGKAYAPRFLFAWPSAKYAVMGGAQAAKTLLELEVEKLK
CCCCEEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHH
REGKEPSDEELKELYERIKGRYEETLDPRYAAARLWVDGVIFPHETRKWLIKALEACALN
HCCCCCCHHHHHHHHHHHHCHHHHCCCHHHHHHHHEECCEECCCHHHHHHHHHHHHHCCC
PEREPFRIGVFQV
CCCCCEEEEEEEC
>Mature Secondary Structure
MLETALRPEDRESPTFKANKDAWVALVRDFRESLERVRQGGGPKAVERQHKKGRLTARER
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHH
IQKLIDPGTEFYELMAFAGWGMYEEWGGAPAGGVITGIGRIAGRDWMIVANDATVKAGAF
HHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCEEECCEE
FPITAKKVIRAQTIALENRIPTVYLVDSAGVFLPLQDEVFPDQDDFGRIFYLNARMSALG
ECCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCHHHCC
IPQISAIMGNCVAGGAYLPVMTDVLIMTEGSGLYLAGPALVKAAIGQEVTSEELGGARMH
CCHHHHHHHHHHCCCCHHHHHHCEEEEECCCCEEEECHHHHHHHHCCHHHHHHCCCEEEE
YEVSGTVDFYEPTDEAALARIRELAALYPPPRLAPWAEGRKAPKEPLYPIEDLYGLVSPD
EEEECEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCC
GSRPYDLREVIARIVDGSEFLEYKGGYGETLVTGFARIGGYPVGIVGNQRLVLKKRGRIE
CCCCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCEEEEEECCCEE
VGGVIYAEAADKAARFILEVNQMGIPLLFLQDVTGFMVGKESEQAGIIRRGAKLVNAVSN
ECCEEEECHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
SVVPKITLILGGSFGAGNYALAGKAYAPRFLFAWPSAKYAVMGGAQAAKTLLELEVEKLK
CCCCEEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHH
REGKEPSDEELKELYERIKGRYEETLDPRYAAARLWVDGVIFPHETRKWLIKALEACALN
HCCCCCCHHHHHHHHHHHHCHHHHCCCHHHHHHHHEECCEECCCHHHHHHHHHHHHHCCC
PEREPFRIGVFQV
CCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]