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The map label for this gene is purQ [H]

Identifier: 55981486

GI number: 55981486

Start: 1441450

End: 1442133

Strand: Direct

Name: purQ [H]

Synonym: TTHA1517

Alternate gene names: 55981486

Gene position: 1441450-1442133 (Clockwise)

Preceding gene: 55981485

Following gene: 55981487

Centisome position: 77.93

GC content: 67.98

Gene sequence:

>684_bases
ATGAGGTGGGCCATCGTTCGCTTCCCCGGCGCCAACTGCGACGAGGACGCCCGCTTCGCCCTGGAGAAGGCGGGGATCCG
GGCGGAGTTCGTCTGGCACACGGAAAGGGACCTCCGGGGCTTTGACGGGGTCTTCCTGCCCGGGGGGTTCAGCTACGGGG
ACTACCTGAGGGCGGGAGCCCTCGCCGCCAAGAGCCCGGTGATGGAAGCGGTGCGGCGCTTCGCCGAGGAAGGGCGGTAC
GTGGTGGGGGTCTGCAACGGCTTCCAGATCCTCACCGAGGCGGGCCTCCTGCCGGGGGCGCTTCTTGCCAACCTCAACCT
CCACTTCACCTGCAAGGAGGTGGGGGTGCGGGTGGAGCGGAATGACCTCCCCTTCACCCGGCTCTACCCAAGGGGGCAGG
TCCTGAGGCTTCCCATCGCCCACGGCGAGGGCCGCTACTACGCCGATCCCGAAACCCTCGCCCGGCTCGAGGGAGAGGGC
CTCGTGGTCTTCCGCTACGCCCCCCTGAAGGACGAGGCGGACTACAACCCCAACGGGAGCCTCCACGACATCGCGGGCAT
CGTGAGCGAGAAGGGCAACGTCCTCGGCATGATGCCCCATCCCGAAAGGGCCGTGGACGAGGTCTTGGGCAACACCGACG
GGCTTCCCTTCTTCCTGGGGCTCGTCAAGGAGGTGGCACGATGA

Upstream 100 bases:

>100_bases
AAAACCTCCTGGAGGCCGAGGAGAAGGCCAAGGCCATGGGCGCCCTCCTCGCCAACCCGGTGATGGAGGTCTACGCCTTG
GAAGCCCTAAAGGAACTCCC

Downstream 100 bases:

>100_bases
AACCCAAAGCCATCACCTTTGACTTCTGGGGCACCCTCTTCACCGAGGGGGAGGCGTTTTTGGAAAAGGTCATGCCCGCC
CGGTACGAGATCCTTCTGGA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRWAIVRFPGANCDEDARFALEKAGIRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGALAAKSPVMEAVRRFAEEGRY
VVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVERNDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEG
LVVFRYAPLKDEADYNPNGSLHDIAGIVSEKGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVKEVAR

Sequences:

>Translated_227_residues
MRWAIVRFPGANCDEDARFALEKAGIRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGALAAKSPVMEAVRRFAEEGRY
VVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVERNDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEG
LVVFRYAPLKDEADYNPNGSLHDIAGIVSEKGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVKEVAR
>Mature_227_residues
MRWAIVRFPGANCDEDARFALEKAGIRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGALAAKSPVMEAVRRFAEEGRY
VVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVERNDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEG
LVVFRYAPLKDEADYNPNGSLHDIAGIVSEKGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVKEVAR

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=243, Percent_Identity=33.7448559670782, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI48994899, Length=221, Percent_Identity=33.4841628959276, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553022, Length=233, Percent_Identity=30.4721030042918, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=229, Percent_Identity=33.1877729257642, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582111, Length=237, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582109, Length=237, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17137292, Length=237, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25079; Mature: 25079

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWAIVRFPGANCDEDARFALEKAGIRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGA
CCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCHHHHHHHHH
LAAKSPVMEAVRRFAEEGRYVVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVER
HHHCCHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCHHHHCCCEEEEEHHHCEEEEC
NDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEGLVVFRYAPLKDEADYNPNGS
CCCCEEEECCCCCEEEEEEECCCCCEEECHHHHHHCCCCCEEEEEECCCCCCCCCCCCCC
LHDIAGIVSEKGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVKEVAR
HHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRWAIVRFPGANCDEDARFALEKAGIRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGA
CCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCHHHHHHHHH
LAAKSPVMEAVRRFAEEGRYVVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVER
HHHCCHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCHHHHCCCEEEEEHHHCEEEEC
NDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEGLVVFRYAPLKDEADYNPNGS
CCCCEEEECCCCCEEEEEEECCCCCEEECHHHHHHCCCCCEEEEEECCCCCCCCCCCCCC
LHDIAGIVSEKGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVKEVAR
HHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA