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The map label for this gene is hemA [H]

Identifier: 55981475

GI number: 55981475

Start: 1433992

End: 1435164

Strand: Reverse

Name: hemA [H]

Synonym: TTHA1506

Alternate gene names: 55981475

Gene position: 1435164-1433992 (Counterclockwise)

Preceding gene: 55981476

Following gene: 55981474

Centisome position: 77.59

GC content: 71.44

Gene sequence:

>1173_bases
ATGGCCTTGCCCCTCTACCTGGTGGGCCTCTCCCACAAGACCGCCCCCCTGGAGGTGCGGGAGCGGGCCGCCTTGGACCC
CGTGGTGGCCCTCCCCGCCGCCCTTTCCGCCCTGGGCAAGGGGGTGGTCCTCTCCACCTGCAACCGCACGGAGCTCTACG
GGGTGGGAAGCCCCGAGAAGGCCAGGGCCTTCCTCCTCTCAAGGGGGGTGGCCCCCCGGCACCTCTACGTGAAGGAGGGG
GTGGAGGCCCTGCGCCACCTCTACCGGGTGGCCGCCGGGCTGGACTCCCTGGTGGTGGGGGAGGCCCAGATCCTGGGCCA
GGTGCGGGAGGCCCTCTTCCTGGCCAGGAGGCAGGGCGCCACGGAAAGCCTTCTGGAGAAGGCCTTTCAGTCGGCCATCG
CCTTGGGCAAGCGGGCCCGGAGCGAGACGGGCATCGGCATGGGGGCGGTGAGCGTGGCCTACGCCGCCTTGGACCTGGCC
CTCGCCGTCTACGGGGACCTTTCCGGGCTTTCCGTGGCCGTGCTGGGGGCGGGGGAGATGGCGGAGCTTTTCCTCACCCA
CCTGAAGGCCCACGGGGTGGGGCGGATCCTGGTCGTGAACCGGACGGAGGAAAAGGCCCAGGCCCTGGCGGAGCGCTTTG
GCGGCGAGGCCTTTGGCCTTCCCGCCCTTCCCCAGGTCTTGCGCCAGGCGGACCTGGTGGTGGCCTCGGCCGCCGCCCCC
CACTACCTGGTGGGCCCCGAGGACCTGCCCAAGCGGGCCAAGCCCCTTTTCCTCATAGACATCGCCCTTCCCCGGAACAT
TGACCCCCGGGTGGGGGACCTCCCCCACGCCTACCTCTACAACCTGGACGACCTCAAGCGGGTGGTGGACCGGAACCTAA
GGGCCCGCGCGGGGGAGATCCCCAAGGTGGAAGCCCTCATTGAGAAGGCCTTAGGGGACTACATGGAGTGGTACGCGGGC
CACCGGGTGCGGGAGGCCATCCGGGCCCTCGAGGCCTGGGCCCGGGTCCAGGCGGCCAAGGCCCAGCCGGAGGCCGGGCC
TGTGGAGCTGGAAAAGGCGGCGGGGCGTCTGGCCCACCCCTTCATCCTGGGGCTGAAGCGCCGCGCCCTGGACCGGGTGG
GGGGGCCTCCCTGCCCGGAGGACTGCCTCCTCTACCGGCTTTCCCGGACATGA

Upstream 100 bases:

>100_bases
GGAAAGCCCGGGGCTAGAAGGGCTTTTTGCCGCCCTTCTCCGGGCCCTCGGGCGGTAGGGCAAACGTCCCTACCCCGGTG
GCCTATACTCAGGGAAGCGT

Downstream 100 bases:

>100_bases
CCCTGGCCCTGGCCTTTCTCGGGGTGGTGGGGGTGGCCTTTGGGGTCTTTCTCCCCGCGGGGCTTTCCTGGGGCGGGGCC
TTCCTCCTCCTTGGGGCCCT

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MALPLYLVGLSHKTAPLEVRERAALDPVVALPAALSALGKGVVLSTCNRTELYGVGSPEKARAFLLSRGVAPRHLYVKEG
VEALRHLYRVAAGLDSLVVGEAQILGQVREALFLARRQGATESLLEKAFQSAIALGKRARSETGIGMGAVSVAYAALDLA
LAVYGDLSGLSVAVLGAGEMAELFLTHLKAHGVGRILVVNRTEEKAQALAERFGGEAFGLPALPQVLRQADLVVASAAAP
HYLVGPEDLPKRAKPLFLIDIALPRNIDPRVGDLPHAYLYNLDDLKRVVDRNLRARAGEIPKVEALIEKALGDYMEWYAG
HRVREAIRALEAWARVQAAKAQPEAGPVELEKAAGRLAHPFILGLKRRALDRVGGPPCPEDCLLYRLSRT

Sequences:

>Translated_390_residues
MALPLYLVGLSHKTAPLEVRERAALDPVVALPAALSALGKGVVLSTCNRTELYGVGSPEKARAFLLSRGVAPRHLYVKEG
VEALRHLYRVAAGLDSLVVGEAQILGQVREALFLARRQGATESLLEKAFQSAIALGKRARSETGIGMGAVSVAYAALDLA
LAVYGDLSGLSVAVLGAGEMAELFLTHLKAHGVGRILVVNRTEEKAQALAERFGGEAFGLPALPQVLRQADLVVASAAAP
HYLVGPEDLPKRAKPLFLIDIALPRNIDPRVGDLPHAYLYNLDDLKRVVDRNLRARAGEIPKVEALIEKALGDYMEWYAG
HRVREAIRALEAWARVQAAKAQPEAGPVELEKAAGRLAHPFILGLKRRALDRVGGPPCPEDCLLYRLSRT
>Mature_389_residues
ALPLYLVGLSHKTAPLEVRERAALDPVVALPAALSALGKGVVLSTCNRTELYGVGSPEKARAFLLSRGVAPRHLYVKEGV
EALRHLYRVAAGLDSLVVGEAQILGQVREALFLARRQGATESLLEKAFQSAIALGKRARSETGIGMGAVSVAYAALDLAL
AVYGDLSGLSVAVLGAGEMAELFLTHLKAHGVGRILVVNRTEEKAQALAERFGGEAFGLPALPQVLRQADLVVASAAAPH
YLVGPEDLPKRAKPLFLIDIALPRNIDPRVGDLPHAYLYNLDDLKRVVDRNLRARAGEIPKVEALIEKALGDYMEWYAGH
RVREAIRALEAWARVQAAKAQPEAGPVELEKAAGRLAHPFILGLKRRALDRVGGPPCPEDCLLYRLSRT

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=363, Percent_Identity=38.2920110192837, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 41937; Mature: 41806

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPLYLVGLSHKTAPLEVRERAALDPVVALPAALSALGKGVVLSTCNRTELYGVGSPEK
CCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCHH
ARAFLLSRGVAPRHLYVKEGVEALRHLYRVAAGLDSLVVGEAQILGQVREALFLARRQGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TESLLEKAFQSAIALGKRARSETGIGMGAVSVAYAALDLALAVYGDLSGLSVAVLGAGEM
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
AELFLTHLKAHGVGRILVVNRTEEKAQALAERFGGEAFGLPALPQVLRQADLVVASAAAP
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
HYLVGPEDLPKRAKPLFLIDIALPRNIDPRVGDLPHAYLYNLDDLKRVVDRNLRARAGEI
CEEECCHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCC
PKVEALIEKALGDYMEWYAGHRVREAIRALEAWARVQAAKAQPEAGPVELEKAAGRLAHP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHH
FILGLKRRALDRVGGPPCPEDCLLYRLSRT
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ALPLYLVGLSHKTAPLEVRERAALDPVVALPAALSALGKGVVLSTCNRTELYGVGSPEK
CCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCHH
ARAFLLSRGVAPRHLYVKEGVEALRHLYRVAAGLDSLVVGEAQILGQVREALFLARRQGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TESLLEKAFQSAIALGKRARSETGIGMGAVSVAYAALDLALAVYGDLSGLSVAVLGAGEM
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH
AELFLTHLKAHGVGRILVVNRTEEKAQALAERFGGEAFGLPALPQVLRQADLVVASAAAP
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
HYLVGPEDLPKRAKPLFLIDIALPRNIDPRVGDLPHAYLYNLDDLKRVVDRNLRARAGEI
CEEECCHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCC
PKVEALIEKALGDYMEWYAGHRVREAIRALEAWARVQAAKAQPEAGPVELEKAAGRLAHP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHH
FILGLKRRALDRVGGPPCPEDCLLYRLSRT
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA