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The map label for this gene is mltC [C]

Identifier: 55981440

GI number: 55981440

Start: 1401491

End: 1403098

Strand: Direct

Name: mltC [C]

Synonym: TTHA1471

Alternate gene names: 55981440

Gene position: 1401491-1403098 (Clockwise)

Preceding gene: 55981438

Following gene: 55981461

Centisome position: 75.77

GC content: 73.76

Gene sequence:

>1608_bases
GTGCGCTGGCTCCTTCTCCTCCTCCTCCTTGCCGCCTGCCGGGCCCAGGGCCTGCCCGAGCCCTACGCCACCCTGGAAAG
GGGCGGGAAGGAAGCCCTCCGCCAGGTGGCCCTCGAGGCCCAGGGGTACGCGGGCCTCCTCGCGGGCTGGCTCCTGGTGG
GCGAGGAAGACCTTCCCCTCGCCGAACGGGCGGAGTACGCCTGGCGCTACGCCCTCTTCCTGGAAGAGGTGCGGGCCTTT
GAGCCGGGCTGGGAGGCGGAGGCGGCCTGGCGGGTGGCGGCGCCCCTCCTGGAGGCGGCGGAAGACGCGAGGGCCTTCTC
CGCCTGGGCGAGGCTTCTCCCCGAGGAGGAGGCCGTCCAGGCCCTTCTGCGCCTCGGCCAGGGGGAGAGGCTCTGGGAGG
CCCTCTTCCGCGGCCGGGCGTACGAACCCCTCCTAAAGGCCCTCCCCGAGGGGGAAAGGCCCGACCTCCGCGCCCAGGCC
CTCTACCGCCTGGGGCGCTACGAGGAGGCCCTTCCCCACTACCGGGCCTGGGCGGAAGCGGACCCGAGGGGCTACCTGGG
CCTGGGCTACGCCCTCTGGCGGCTCGGGAGGCGGGAGGAGGCCCTTCAGGCCTTCGCCCGCTACGACCACCCGGAAAGCC
GCCTGGCCCAAGGCCGCCTCCTGGAGGGGATGGGGCGGGTGGAGGAGGCCCTTGCCCGCTACCTGGCGAGCACCCCGGAG
GGGCTTTGGCGGGCCACGGCCCTGCTTGAGCGCCTGGGGCGGAAGGAGGAGGCCCTAGGGGTCTACCTCCGCCTCGCCCA
AGGGGAAAGCCCCTACGCCGACGACGCCGCCCTTCGCGCCTACCTCCTCGCCGGGGAGCTCGGGAATGGAGAGGCGCGGC
AAGAGGCCTACGCCCGCCTCGAGGGGGGCCTGGGCCTCCTCGTGGGCAAGAGGCCAAGCCCGCCCCCCCAGGCCCTCGAG
GCCCCCCCGGCCCCGCTTACCCCCCTGGTGGAGGCCCTGGTCCGGGCGGGCAAGGCGGCCTGGGCCCGGGGGGAGGTGCG
CTACGCCCTCTGGCGGCGCCCAAAGGACTGGCCCGCCCTCGTCCCTCTCCTCTACCGCCTGGGGGCCTATAGGGAGGGGA
TCCGGGCCGCCTGGCCCACGGCCCTCGCCTACCCGCGGGCCTACCGGGAGTGGGTGGAGGGCTACGCGGGGAAGGAGGGG
CTGGACCCCGACCTCCTCTTCGCCCTCCTCCACGTGGAAAGCCGCTTTGACCCTAAGGCGGTGAGCCCCACGGGGGCCTT
GGGCCTCGCCCAGTTCCTACGGAGCACCTGGGCGGACGTGGCGCGGATGCTGGGAGAACCCCCCGCCGACCCCTTTGACC
CGGAAAGCGCCATCCGCTACGCCGCCCGCTACCTCCGCTGGCTCATGGAGCGGTGCGCCGCCTTTTCCGGCGTGGAGCGG
CTCGCCTGCGCCGTCACCGCCTACAACGGGGGCATCGGCTACACCCTAAGGGGCATCGCCCGGGAGGGGGGTCTCTACGC
CTTCCTCCGCTTCCAAGAGCGGGACGAGCCCCGGGAGTACCTCGCCAAGGTGCTCTCCGCCTACGCCGCCTACAAGGCTA
TTCCTTAG

Upstream 100 bases:

>100_bases
CCAGGTTAAGCCCGCCTCCCCTCCTTCCGCCAGAGGCCTTTCCTTGTGGGAAGGATTGGCTCTTTTCCGCTTCTCAGGGG
AGGGGCCTAAGCTCTAAGGC

Downstream 100 bases:

>100_bases
CGGCGCGCTCCCTCTCCGTCCAGGCGATGAGGGGCTTCAGGGCGAAGGGGGCGAAGAGGGTCGTGAAGACCACCATGAAG
AGGACGATGGCGTACTCCTC

Product: transglycosylase

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Transglycosylase; Soluble Lytic Murein Transglycosylase; Transglycosylase SLT Domain-Containing Protein; Slt Family Transglycosylase; Transglycosylase Slt Domain Protein; Transglycosylase SLT Domain Protein; Phage Lytic Transglycosylase; Membrane-Bound Lytic Murein Transglycosylase C; Lytic Transglycosylase; Phage-Related Lytic Transglycosylase; Soluble Lytic Transglycosylase; Phage-Related Lytic Murein Transglycosylase

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MRWLLLLLLLAACRAQGLPEPYATLERGGKEALRQVALEAQGYAGLLAGWLLVGEEDLPLAERAEYAWRYALFLEEVRAF
EPGWEAEAAWRVAAPLLEAAEDARAFSAWARLLPEEEAVQALLRLGQGERLWEALFRGRAYEPLLKALPEGERPDLRAQA
LYRLGRYEEALPHYRAWAEADPRGYLGLGYALWRLGRREEALQAFARYDHPESRLAQGRLLEGMGRVEEALARYLASTPE
GLWRATALLERLGRKEEALGVYLRLAQGESPYADDAALRAYLLAGELGNGEARQEAYARLEGGLGLLVGKRPSPPPQALE
APPAPLTPLVEALVRAGKAAWARGEVRYALWRRPKDWPALVPLLYRLGAYREGIRAAWPTALAYPRAYREWVEGYAGKEG
LDPDLLFALLHVESRFDPKAVSPTGALGLAQFLRSTWADVARMLGEPPADPFDPESAIRYAARYLRWLMERCAAFSGVER
LACAVTAYNGGIGYTLRGIAREGGLYAFLRFQERDEPREYLAKVLSAYAAYKAIP

Sequences:

>Translated_535_residues
MRWLLLLLLLAACRAQGLPEPYATLERGGKEALRQVALEAQGYAGLLAGWLLVGEEDLPLAERAEYAWRYALFLEEVRAF
EPGWEAEAAWRVAAPLLEAAEDARAFSAWARLLPEEEAVQALLRLGQGERLWEALFRGRAYEPLLKALPEGERPDLRAQA
LYRLGRYEEALPHYRAWAEADPRGYLGLGYALWRLGRREEALQAFARYDHPESRLAQGRLLEGMGRVEEALARYLASTPE
GLWRATALLERLGRKEEALGVYLRLAQGESPYADDAALRAYLLAGELGNGEARQEAYARLEGGLGLLVGKRPSPPPQALE
APPAPLTPLVEALVRAGKAAWARGEVRYALWRRPKDWPALVPLLYRLGAYREGIRAAWPTALAYPRAYREWVEGYAGKEG
LDPDLLFALLHVESRFDPKAVSPTGALGLAQFLRSTWADVARMLGEPPADPFDPESAIRYAARYLRWLMERCAAFSGVER
LACAVTAYNGGIGYTLRGIAREGGLYAFLRFQERDEPREYLAKVLSAYAAYKAIP
>Mature_535_residues
MRWLLLLLLLAACRAQGLPEPYATLERGGKEALRQVALEAQGYAGLLAGWLLVGEEDLPLAERAEYAWRYALFLEEVRAF
EPGWEAEAAWRVAAPLLEAAEDARAFSAWARLLPEEEAVQALLRLGQGERLWEALFRGRAYEPLLKALPEGERPDLRAQA
LYRLGRYEEALPHYRAWAEADPRGYLGLGYALWRLGRREEALQAFARYDHPESRLAQGRLLEGMGRVEEALARYLASTPE
GLWRATALLERLGRKEEALGVYLRLAQGESPYADDAALRAYLLAGELGNGEARQEAYARLEGGLGLLVGKRPSPPPQALE
APPAPLTPLVEALVRAGKAAWARGEVRYALWRRPKDWPALVPLLYRLGAYREGIRAAWPTALAYPRAYREWVEGYAGKEG
LDPDLLFALLHVESRFDPKAVSPTGALGLAQFLRSTWADVARMLGEPPADPFDPESAIRYAARYLRWLMERCAAFSGVER
LACAVTAYNGGIGYTLRGIAREGGLYAFLRFQERDEPREYLAKVLSAYAAYKAIP

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 59717; Mature: 59717

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLLLLLLLAACRAQGLPEPYATLERGGKEALRQVALEAQGYAGLLAGWLLVGEEDLPL
CHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCH
AERAEYAWRYALFLEEVRAFEPGWEAEAAWRVAAPLLEAAEDARAFSAWARLLPEEEAVQ
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ALLRLGQGERLWEALFRGRAYEPLLKALPEGERPDLRAQALYRLGRYEEALPHYRAWAEA
HHHHCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DPRGYLGLGYALWRLGRREEALQAFARYDHPESRLAQGRLLEGMGRVEEALARYLASTPE
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
GLWRATALLERLGRKEEALGVYLRLAQGESPYADDAALRAYLLAGELGNGEARQEAYARL
HHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
EGGLGLLVGKRPSPPPQALEAPPAPLTPLVEALVRAGKAAWARGEVRYALWRRPKDWPAL
HCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHCCCCCCHHH
VPLLYRLGAYREGIRAAWPTALAYPRAYREWVEGYAGKEGLDPDLLFALLHVESRFDPKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
VSPTGALGLAQFLRSTWADVARMLGEPPADPFDPESAIRYAARYLRWLMERCAAFSGVER
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LACAVTAYNGGIGYTLRGIAREGGLYAFLRFQERDEPREYLAKVLSAYAAYKAIP
HHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRWLLLLLLLAACRAQGLPEPYATLERGGKEALRQVALEAQGYAGLLAGWLLVGEEDLPL
CHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCH
AERAEYAWRYALFLEEVRAFEPGWEAEAAWRVAAPLLEAAEDARAFSAWARLLPEEEAVQ
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ALLRLGQGERLWEALFRGRAYEPLLKALPEGERPDLRAQALYRLGRYEEALPHYRAWAEA
HHHHCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DPRGYLGLGYALWRLGRREEALQAFARYDHPESRLAQGRLLEGMGRVEEALARYLASTPE
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
GLWRATALLERLGRKEEALGVYLRLAQGESPYADDAALRAYLLAGELGNGEARQEAYARL
HHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
EGGLGLLVGKRPSPPPQALEAPPAPLTPLVEALVRAGKAAWARGEVRYALWRRPKDWPAL
HCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHCCCCCCHHH
VPLLYRLGAYREGIRAAWPTALAYPRAYREWVEGYAGKEGLDPDLLFALLHVESRFDPKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
VSPTGALGLAQFLRSTWADVARMLGEPPADPFDPESAIRYAARYLRWLMERCAAFSGVER
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LACAVTAYNGGIGYTLRGIAREGGLYAFLRFQERDEPREYLAKVLSAYAAYKAIP
HHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA