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The map label for this gene is yabD [H]

Identifier: 55981418

GI number: 55981418

Start: 1377193

End: 1377948

Strand: Direct

Name: yabD [H]

Synonym: TTHA1449

Alternate gene names: 55981418

Gene position: 1377193-1377948 (Clockwise)

Preceding gene: 55981417

Following gene: 55981419

Centisome position: 74.45

GC content: 71.83

Gene sequence:

>756_bases
GTGACCGACACCCACGCCCACCTGGACTTCCTGGAACCGGAGGAGCTCGCCGAGGCCGCCGCCCACCTCCCAAAGCTTCG
GGCCGTGCTCACCCTGGGGGTGGACCCGGGCCGCTGGGAGAAGACCCTAAGCCTGGCCCAGGGAAACGTCTACGCCGCAG
TGGGCCTCCACCCCACGAGCGCCCACCTCCTCTCCCCCGAGGTGGAGGAGGCCCTCCGCCACTACGCCCGAAGCGAGCGG
GTGCGGGCCATCGGGGAGACGGGGCTGGACTACTACTGGACCCCGGAGACCAGGGCCGCCCAGCTCAAGGCCCTGGACTT
CCAGGCGGCTTTGGCGGAGGCCCTCGGCCTTCCCCTGGTCCTCCACGTGCGGAGCAAGGACGGCAAGGCCGAGGAGGACC
TCGCCGCCTGGCTCCTCCTCCACCGGCCCAAGCGGGCCGTGCTCCACGCCTTCTCCGGCCACCCCGCCCTGGAAGCGGCG
GGCCTGGAGGTGGGGGCCTACTTCAGCTTCGCCGGGCCCCTCACCTACAGGAAAAACGCCGCCCTGCGCGAGGCCGCGGC
CCGGCTCCCCGAGGACAGGCTTCTGGTGGAGACCGACACCCCCTTCCTTCCCCCGGAGCCCTTCCGGGGCAAGCGGAACC
GCCCCCACTACGTGCGCTTTACCCTGGAGAAACTCGCGGAAGCGCGGGGCCTTCCCTTCGCCGAGGCGGAGGCCCTCACC
GACCGGAACGCCCGGGTATGCTTTGGCTGGCCATGA

Upstream 100 bases:

>100_bases
ATGCTGGCCCAAGCCAGCATGGGGGCCCCGGCAAAAGGTCCCTGGGAAGCCTCCCTGGGCCAGTCGGACGAAGGAACCCG
GAAGGGTATAAAGTGGTCCC

Downstream 100 bases:

>100_bases
GGCGTTTCCTCGTTCTGCTCTGGCTCCTCTCCCTGGCCCTGGCGGCGCCCCGCCTCGTGGTGGAGCCCGAGGACGGGGTC
AAGCCCCTCCTGGACCTCAT

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTDTHAHLDFLEPEELAEAAAHLPKLRAVLTLGVDPGRWEKTLSLAQGNVYAAVGLHPTSAHLLSPEVEEALRHYARSER
VRAIGETGLDYYWTPETRAAQLKALDFQAALAEALGLPLVLHVRSKDGKAEEDLAAWLLLHRPKRAVLHAFSGHPALEAA
GLEVGAYFSFAGPLTYRKNAALREAAARLPEDRLLVETDTPFLPPEPFRGKRNRPHYVRFTLEKLAEARGLPFAEAEALT
DRNARVCFGWP

Sequences:

>Translated_251_residues
MTDTHAHLDFLEPEELAEAAAHLPKLRAVLTLGVDPGRWEKTLSLAQGNVYAAVGLHPTSAHLLSPEVEEALRHYARSER
VRAIGETGLDYYWTPETRAAQLKALDFQAALAEALGLPLVLHVRSKDGKAEEDLAAWLLLHRPKRAVLHAFSGHPALEAA
GLEVGAYFSFAGPLTYRKNAALREAAARLPEDRLLVETDTPFLPPEPFRGKRNRPHYVRFTLEKLAEARGLPFAEAEALT
DRNARVCFGWP
>Mature_250_residues
TDTHAHLDFLEPEELAEAAAHLPKLRAVLTLGVDPGRWEKTLSLAQGNVYAAVGLHPTSAHLLSPEVEEALRHYARSERV
RAIGETGLDYYWTPETRAAQLKALDFQAALAEALGLPLVLHVRSKDGKAEEDLAAWLLLHRPKRAVLHAFSGHPALEAAG
LEVGAYFSFAGPLTYRKNAALREAAARLPEDRLLVETDTPFLPPEPFRGKRNRPHYVRFTLEKLAEARGLPFAEAEALTD
RNARVCFGWP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=231, Percent_Identity=29.4372294372294, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI110349734, Length=231, Percent_Identity=29.8701298701299, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226061853, Length=237, Percent_Identity=29.535864978903, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI226061614, Length=219, Percent_Identity=28.310502283105, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI225903424, Length=227, Percent_Identity=30.8370044052863, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226061595, Length=195, Percent_Identity=29.7435897435897, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=36.8217054263566, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87082439, Length=262, Percent_Identity=30.9160305343511, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994985, Length=214, Percent_Identity=30.3738317757009, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=28.1481481481481, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 27788; Mature: 27657

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00889 CNMP_BINDING_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTHAHLDFLEPEELAEAAAHLPKLRAVLTLGVDPGRWEKTLSLAQGNVYAAVGLHPTS
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCC
AHLLSPEVEEALRHYARSERVRAIGETGLDYYWTPETRAAQLKALDFQAALAEALGLPLV
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEE
LHVRSKDGKAEEDLAAWLLLHRPKRAVLHAFSGHPALEAAGLEVGAYFSFAGPLTYRKNA
EEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHCCCEEEEEEEECCCCCCCCCH
ALREAAARLPEDRLLVETDTPFLPPEPFRGKRNRPHYVRFTLEKLAEARGLPFAEAEALT
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHC
DRNARVCFGWP
CCCCEEEECCC
>Mature Secondary Structure 
TDTHAHLDFLEPEELAEAAAHLPKLRAVLTLGVDPGRWEKTLSLAQGNVYAAVGLHPTS
CCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCC
AHLLSPEVEEALRHYARSERVRAIGETGLDYYWTPETRAAQLKALDFQAALAEALGLPLV
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEE
LHVRSKDGKAEEDLAAWLLLHRPKRAVLHAFSGHPALEAAGLEVGAYFSFAGPLTYRKNA
EEEECCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHCCCEEEEEEEECCCCCCCCCH
ALREAAARLPEDRLLVETDTPFLPPEPFRGKRNRPHYVRFTLEKLAEARGLPFAEAEALT
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHC
DRNARVCFGWP
CCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]