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The map label for this gene is engA [H]

Identifier: 55981360

GI number: 55981360

Start: 1326433

End: 1327728

Strand: Direct

Name: engA [H]

Synonym: TTHA1391

Alternate gene names: 55981360

Gene position: 1326433-1327728 (Clockwise)

Preceding gene: 55981357

Following gene: 55981362

Centisome position: 71.71

GC content: 67.67

Gene sequence:

>1296_bases
ATGCACAAGGTGGTCATCGTGGGCAGGCCCAACGTGGGCAAATCCAGCCTCTTCAACCGCCTCCTCAAGAAGCGGAGCGC
GGTGGTGGCGGACGTGCCCGGGGTCACCCGCGACCTTAAAGAGGGCGTGGTGGAAACCGACCGGGGCCGGTTCCTCCTGG
TGGACACGGGGGGGCTCTGGTCCGGGGACAAGTGGGAGAAGAAGATCCAGGAGAAGGTGGACCGGGCCCTGGAGGACGCC
GAGGTGGTGCTCTTCGCCGTGGACGGGCGGGCCGAGCTCACCCAGGCGGACTACGAGGTGGCCGAGTACCTGCGGAGGAA
GGGGAAGCCCGTGATCCTCGTGGCCACCAAGGTGGACGACCCCAAGCACGAGCTCTACCTGGGCCCCCTCTACGGCCTCG
GCTTCGGCGACCCCATCCCCACCTCCAGCGAGCACGCGAGGGGGCTGGAGGAGCTCCTCGAGGCCATCTGGGAGAGGCTT
CCCGTACGCCAGATAGAGACCGAGCCCGAGGTGGCGGGCATCCGGCTCGCCATCGTGGGCCGGCCCAACGCCGGGAAGTC
CAGCCTCTTGAACGCCATCCTGGGGGAGGAGCGGGTCATCGTCTCCGAGGAGCCGGGCACCACCCGGGACGCCATTGACG
TGGAGTTCTTCTTCGGCGGCCAGCGCTTCGTCCTCGTGGACACCGCCGGGATCCGCAAGCGGCCCGAAAACCTCGTGGAG
GAGCTCGCCATCCGGCGGAGCCTTAGGGCCATGGACGAGGCGGACGTGGTCCTCCTCGTGGTGGACCCCTTCCAGGTGGG
GGACCGGGAGCTCAAGCTCGCCAACGAGGCCCTGGACCGGGGCAAGCCCGTCCTTTTGGTCATCACCAAGTGGGACCTGG
TGGACAAGGAGGACGCCCCCAAGATGCGGCGCCTCCTCCGGGAAAAGCTCGCCCACCTGGACCACCTCCCCCGGGTCTTC
ACCTCCGCCCTGACGCGGCAGAACCTGGACCGGATCTTCCGGGAGGCGGTGCGCCTTCACGAACTCAACCAGACCCGCGT
CCCCACCGCCGAGCTCAACCGCTGGGTGGCGGTCTGGACGAGCCGCGTGCAGATGCCGAACTTCAAGGGCAAGCCCCTCA
AGATCCTCTACGCCACCCAGCCCGAGGTGGCCCCGCCCACCTTCGTCTTCTTCGTGAACCACCCGGAGTTCGTCACCCGG
GCCTTTGAGAACTACCTGAAAAACCGCATCGGCGAGGACCTGGGCCTAAGAGAGGTGCCCTTCCGCCTGGTCTTCCGGGG
AAGGAGGGAGGAGTAG

Upstream 100 bases:

>100_bases
GCGGGCGAGCTTCTGCATGCCTCCTAGGAGTATACCGCGTGTGGTACACTAAAGGGTAACGCCGGGTGGGGCCTTCCCCA
CCCCTTTTCGTGGAGGGCGC

Downstream 100 bases:

>100_bases
CGCCATCCCCTCCACCGCCCCCGTCCGCAAGGAGAGGTGGGCCAGGGGGGTGAGGGGGGTGGGCTCGGGGTTCACCTCCA
CCAGGTAGGCCCCCGAGGCG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MHKVVIVGRPNVGKSSLFNRLLKKRSAVVADVPGVTRDLKEGVVETDRGRFLLVDTGGLWSGDKWEKKIQEKVDRALEDA
EVVLFAVDGRAELTQADYEVAEYLRRKGKPVILVATKVDDPKHELYLGPLYGLGFGDPIPTSSEHARGLEELLEAIWERL
PVRQIETEPEVAGIRLAIVGRPNAGKSSLLNAILGEERVIVSEEPGTTRDAIDVEFFFGGQRFVLVDTAGIRKRPENLVE
ELAIRRSLRAMDEADVVLLVVDPFQVGDRELKLANEALDRGKPVLLVITKWDLVDKEDAPKMRRLLREKLAHLDHLPRVF
TSALTRQNLDRIFREAVRLHELNQTRVPTAELNRWVAVWTSRVQMPNFKGKPLKILYATQPEVAPPTFVFFVNHPEFVTR
AFENYLKNRIGEDLGLREVPFRLVFRGRREE

Sequences:

>Translated_431_residues
MHKVVIVGRPNVGKSSLFNRLLKKRSAVVADVPGVTRDLKEGVVETDRGRFLLVDTGGLWSGDKWEKKIQEKVDRALEDA
EVVLFAVDGRAELTQADYEVAEYLRRKGKPVILVATKVDDPKHELYLGPLYGLGFGDPIPTSSEHARGLEELLEAIWERL
PVRQIETEPEVAGIRLAIVGRPNAGKSSLLNAILGEERVIVSEEPGTTRDAIDVEFFFGGQRFVLVDTAGIRKRPENLVE
ELAIRRSLRAMDEADVVLLVVDPFQVGDRELKLANEALDRGKPVLLVITKWDLVDKEDAPKMRRLLREKLAHLDHLPRVF
TSALTRQNLDRIFREAVRLHELNQTRVPTAELNRWVAVWTSRVQMPNFKGKPLKILYATQPEVAPPTFVFFVNHPEFVTR
AFENYLKNRIGEDLGLREVPFRLVFRGRREE
>Mature_431_residues
MHKVVIVGRPNVGKSSLFNRLLKKRSAVVADVPGVTRDLKEGVVETDRGRFLLVDTGGLWSGDKWEKKIQEKVDRALEDA
EVVLFAVDGRAELTQADYEVAEYLRRKGKPVILVATKVDDPKHELYLGPLYGLGFGDPIPTSSEHARGLEELLEAIWERL
PVRQIETEPEVAGIRLAIVGRPNAGKSSLLNAILGEERVIVSEEPGTTRDAIDVEFFFGGQRFVLVDTAGIRKRPENLVE
ELAIRRSLRAMDEADVVLLVVDPFQVGDRELKLANEALDRGKPVLLVITKWDLVDKEDAPKMRRLLREKLAHLDHLPRVF
TSALTRQNLDRIFREAVRLHELNQTRVPTAELNRWVAVWTSRVQMPNFKGKPLKILYATQPEVAPPTFVFFVNHPEFVTR
AFENYLKNRIGEDLGLREVPFRLVFRGRREE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Homo sapiens, GI193082988, Length=134, Percent_Identity=32.8358208955224, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87082120, Length=454, Percent_Identity=35.9030837004405, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI2367268, Length=90, Percent_Identity=44.4444444444444, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788919, Length=165, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=41.7582417582418, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323665, Length=166, Percent_Identity=31.9277108433735, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45550813, Length=172, Percent_Identity=31.9767441860465, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48960; Mature: 48960

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKVVIVGRPNVGKSSLFNRLLKKRSAVVADVPGVTRDLKEGVVETDRGRFLLVDTGGLW
CCEEEEEECCCCCHHHHHHHHHHHHCCEEECCCCHHHHHHCCCCCCCCCCEEEEECCCCC
SGDKWEKKIQEKVDRALEDAEVVLFAVDGRAELTQADYEVAEYLRRKGKPVILVATKVDD
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCC
PKHELYLGPLYGLGFGDPIPTSSEHARGLEELLEAIWERLPVRQIETEPEVAGIRLAIVG
CCCEEEEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEE
RPNAGKSSLLNAILGEERVIVSEEPGTTRDAIDVEFFFGGQRFVLVDTAGIRKRPENLVE
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCEEEEEEECCCCCCCHHHHHH
ELAIRRSLRAMDEADVVLLVVDPFQVGDRELKLANEALDRGKPVLLVITKWDLVDKEDAP
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCH
KMRRLLREKLAHLDHLPRVFTSALTRQNLDRIFREAVRLHELNQTRVPTAELNRWVAVWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEHH
SRVQMPNFKGKPLKILYATQPEVAPPTFVFFVNHPEFVTRAFENYLKNRIGEDLGLREVP
HHCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHCC
FRLVFRGRREE
HHHHCCCCCCC
>Mature Secondary Structure
MHKVVIVGRPNVGKSSLFNRLLKKRSAVVADVPGVTRDLKEGVVETDRGRFLLVDTGGLW
CCEEEEEECCCCCHHHHHHHHHHHHCCEEECCCCHHHHHHCCCCCCCCCCEEEEECCCCC
SGDKWEKKIQEKVDRALEDAEVVLFAVDGRAELTQADYEVAEYLRRKGKPVILVATKVDD
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCC
PKHELYLGPLYGLGFGDPIPTSSEHARGLEELLEAIWERLPVRQIETEPEVAGIRLAIVG
CCCEEEEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEEEEE
RPNAGKSSLLNAILGEERVIVSEEPGTTRDAIDVEFFFGGQRFVLVDTAGIRKRPENLVE
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCEEEEEEECCCCCCCHHHHHH
ELAIRRSLRAMDEADVVLLVVDPFQVGDRELKLANEALDRGKPVLLVITKWDLVDKEDAP
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCH
KMRRLLREKLAHLDHLPRVFTSALTRQNLDRIFREAVRLHELNQTRVPTAELNRWVAVWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEHH
SRVQMPNFKGKPLKILYATQPEVAPPTFVFFVNHPEFVTRAFENYLKNRIGEDLGLREVP
HHCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHCC
FRLVFRGRREE
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA