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The map label for this gene is acpS

Identifier: 55981357

GI number: 55981357

Start: 1325070

End: 1325447

Strand: Direct

Name: acpS

Synonym: TTHA1388

Alternate gene names: 55981357

Gene position: 1325070-1325447 (Clockwise)

Preceding gene: 55981355

Following gene: 55981360

Centisome position: 71.64

GC content: 67.2

Gene sequence:

>378_bases
ATGATCGTCGCCCTGGGGGCCGACCTGGTGGAGATCGCCCGCGTGGAAAGGCTCCTTTCCCGCCACGGGGAGAGGGCCTT
GAGGCGGCTTTTTCACGAGGAGGAGGTGGCCTACGCCCTCGCCCGCCAAAACCCTTTCCCGAGCCTCGCCGCCCGCCTTG
CGGCCAAGGAGGCCTTCCAGAAGTGCTGGCCGGAAAGCCTCTCCTGGAAGGAGGTCTGGGTGGGGATGGAAGGGAAAAGG
CCCGCCCTTCGCTTCGCCCCCCGAATAGAAGCCCGCATGGCGGAGGAAGGGCTTTTCGCCCACCTCTCCCTAAGCCACGA
GCGGAGCCACGCCTTGGCGGTGGTGGTCCTCGAGGCTAGGGCACGAGGCGGAGGATGA

Upstream 100 bases:

>100_bases
CTCGCCCAGAAGCTCGGCCATGCGGGAAAGGAAGGCCTTGGGCAGCACCCGTGTACCCTAGCACGGAAGGCCCGAAGGCC
TCAAGGGATACCATGGGCCC

Downstream 100 bases:

>100_bases
AGGCGTAGCGGTAGACCTCTCCCCTTCCCGCCGCCAAAGCCCCCCGGACCATGTTCCAAAGCACCAAGGCCAAAAGGGCG
AGGGCTAAGGGATACACAAC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIVALGADLVEIARVERLLSRHGERALRRLFHEEEVAYALARQNPFPSLAARLAAKEAFQKCWPESLSWKEVWVGMEGKR
PALRFAPRIEARMAEEGLFAHLSLSHERSHALAVVVLEARARGGG

Sequences:

>Translated_125_residues
MIVALGADLVEIARVERLLSRHGERALRRLFHEEEVAYALARQNPFPSLAARLAAKEAFQKCWPESLSWKEVWVGMEGKR
PALRFAPRIEARMAEEGLFAHLSLSHERSHALAVVVLEARARGGG
>Mature_125_residues
MIVALGADLVEIARVERLLSRHGERALRRLFHEEEVAYALARQNPFPSLAARLAAKEAFQKCWPESLSWKEVWVGMEGKR
PALRFAPRIEARMAEEGLFAHLSLSHERSHALAVVVLEARARGGG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_THET2 (Q72IV9)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_004991.1
- ProteinModelPortal:   Q72IV9
- STRING:   Q72IV9
- GeneID:   2775721
- GenomeReviews:   AE017221_GR
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   APAGMNW
- ProtClustDB:   PRK14662
- BioCyc:   TTHE262724:TT_C1022-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14022; Mature: 14022

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVALGADLVEIARVERLLSRHGERALRRLFHEEEVAYALARQNPFPSLAARLAAKEAFQ
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KCWPESLSWKEVWVGMEGKRPALRFAPRIEARMAEEGLFAHLSLSHERSHALAVVVLEAR
HHCCCCCCHHHHEECCCCCCCHHHHCCHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECC
ARGGG
CCCCC
>Mature Secondary Structure
MIVALGADLVEIARVERLLSRHGERALRRLFHEEEVAYALARQNPFPSLAARLAAKEAFQ
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KCWPESLSWKEVWVGMEGKRPALRFAPRIEARMAEEGLFAHLSLSHERSHALAVVVLEAR
HHCCCCCCHHHHEECCCCCCCHHHHCCHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECC
ARGGG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA