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The map label for this gene is ykoH [H]

Identifier: 55981332

GI number: 55981332

Start: 1300314

End: 1301567

Strand: Direct

Name: ykoH [H]

Synonym: TTHA1363

Alternate gene names: 55981332

Gene position: 1300314-1301567 (Clockwise)

Preceding gene: 55981331

Following gene: 55981334

Centisome position: 70.3

GC content: 74.56

Gene sequence:

>1254_bases
GTGCTCTCCTTCCGCGCCCGGCTCTTCCTGGCCTTCGCCCTTTTGTGGCTCCTTTTCCTGGGCGGGGCCTGGTACCTGGC
GGGACGCAGCGTGGACCAGGCCCTGAAAAGGCGCCTCGAGGCCACCCTCGCCCAGGACGCCCTCCGGGCGGCCGAGGCCT
ACCGGAAGGGCCAGGCGGGCGCCCTCCTCACCACGGGCGGGGTTTACCTGCACCTCTACGCCCAAGACGGCACCCCCCTC
GCCCTCACCCGGCCCGACCACCGCCTCCCCCCAGAGAGGCTCCGCCGGGCGGGGCCCACCCCGGAGGTCCTCTGGGAAGA
GGGCTTCGCCGCCGCCCTCGTGGCCACGCCCCTGGGCCTCCTCGTCCTCACCGCGGAGACGAGCCCCATTGAGGCCGCCC
TCGAGGCCCTCCGGGAAGCCCTCCTCCGCGCCTTCCTCCTCCTCTTCCCCCTGGGCCTGGCTTTGGTCTACCTCACGGCC
CGCCTCGCCGCCCGGCCCCTGGAGGCCGTGGCCCGGGAGATCACGCGCCGAAGCCCAGACCGCCTGGACCCCGTGCCCCA
CCGCCTGCCCAAGGACGAGTTCGGGCGCATGGTGGAGGCGGTGAACGCCCTGCTCCAGGCCCTGAAGGAGGCCAAGGAGC
GGGAGCGGGCCTTCCTCGCCGAGGCCAGCCACGAGCTCAGGACCCCCCTCACCGTCCTCCTGGGCCACCTGGACCGCCTG
GGGCGGAACCCCATGGACCTCGAGGCCCTCCGCACCGCCCGGGCCACCGCCGAGCGGATGCGCCGCCTGGTGGAGGACCT
GCTGGCCCTGGCCCGGGGGGAGGTGGAGCGGAACCTCAACCTCCACATCGTGGACCTGGGGGAGGTGGCCCGGGAGGCGG
CCCTGGAGTACGGGGTGGCGGCCGAGGCGGAAAGCGCCGAGGTCCTCGGGGACCCCGACCGCCTCCTCCAGCTCCTTCGC
AACCTCGTCGCCAACGCCGTCCGGGCGGCGGGGAAGGAGGGCGTGCGGGTGCGGGTGCGCCGGGAAGCCGACCACGCCCT
CCTGGAGGTGGAGGACTCGGGGCCCGGGATCCCCGAGGACCTCCTCCCCCGCCTCTTCCAGCGCTTCGCCCGGGGGCCCG
GAGGGGGCACGGGGCTTGGGCTTGCCATCGCCCACGCCATCGCCAAGGCCCACGGCGGGGAGATCGCCGTGGAAAGCCGC
CCCGGGCGCACGGTCTTCAGGGTGCGGTTGCCCCTTTTGGAGGAGGAGGCCTAA

Upstream 100 bases:

>100_bases
CCGGGCCAAGCTCCGGGAGGCGGGGGCCTACGGGTACCTGCGCACGGTCCGGGGCGTGGGCTACGCCGTGCGGCCGGGAA
GGAGGGAGGAGGAGGGCTAG

Downstream 100 bases:

>100_bases
GGAGGGCCCGGAGGGATGTCCAGAAAGAAGCTGCGTTTCAGAGCCTTCACCAAGAAAGCGTCACCCTTCTTCCTCACCAG
GTAGCAGGATCCAAATGCGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLSFRARLFLAFALLWLLFLGGAWYLAGRSVDQALKRRLEATLAQDALRAAEAYRKGQAGALLTTGGVYLHLYAQDGTPL
ALTRPDHRLPPERLRRAGPTPEVLWEEGFAAALVATPLGLLVLTAETSPIEAALEALREALLRAFLLLFPLGLALVYLTA
RLAARPLEAVAREITRRSPDRLDPVPHRLPKDEFGRMVEAVNALLQALKEAKERERAFLAEASHELRTPLTVLLGHLDRL
GRNPMDLEALRTARATAERMRRLVEDLLALARGEVERNLNLHIVDLGEVAREAALEYGVAAEAESAEVLGDPDRLLQLLR
NLVANAVRAAGKEGVRVRVRREADHALLEVEDSGPGIPEDLLPRLFQRFARGPGGGTGLGLAIAHAIAKAHGGEIAVESR
PGRTVFRVRLPLLEEEA

Sequences:

>Translated_417_residues
MLSFRARLFLAFALLWLLFLGGAWYLAGRSVDQALKRRLEATLAQDALRAAEAYRKGQAGALLTTGGVYLHLYAQDGTPL
ALTRPDHRLPPERLRRAGPTPEVLWEEGFAAALVATPLGLLVLTAETSPIEAALEALREALLRAFLLLFPLGLALVYLTA
RLAARPLEAVAREITRRSPDRLDPVPHRLPKDEFGRMVEAVNALLQALKEAKERERAFLAEASHELRTPLTVLLGHLDRL
GRNPMDLEALRTARATAERMRRLVEDLLALARGEVERNLNLHIVDLGEVAREAALEYGVAAEAESAEVLGDPDRLLQLLR
NLVANAVRAAGKEGVRVRVRREADHALLEVEDSGPGIPEDLLPRLFQRFARGPGGGTGLGLAIAHAIAKAHGGEIAVESR
PGRTVFRVRLPLLEEEA
>Mature_417_residues
MLSFRARLFLAFALLWLLFLGGAWYLAGRSVDQALKRRLEATLAQDALRAAEAYRKGQAGALLTTGGVYLHLYAQDGTPL
ALTRPDHRLPPERLRRAGPTPEVLWEEGFAAALVATPLGLLVLTAETSPIEAALEALREALLRAFLLLFPLGLALVYLTA
RLAARPLEAVAREITRRSPDRLDPVPHRLPKDEFGRMVEAVNALLQALKEAKERERAFLAEASHELRTPLTVLLGHLDRL
GRNPMDLEALRTARATAERMRRLVEDLLALARGEVERNLNLHIVDLGEVAREAALEYGVAAEAESAEVLGDPDRLLQLLR
NLVANAVRAAGKEGVRVRVRREADHALLEVEDSGPGIPEDLLPRLFQRFARGPGGGTGLGLAIAHAIAKAHGGEIAVESR
PGRTVFRVRLPLLEEEA

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=33.7448559670782, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=32.5, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789403, Length=437, Percent_Identity=28.8329519450801, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=31.5126050420168, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790551, Length=272, Percent_Identity=33.0882352941176, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786600, Length=278, Percent_Identity=32.3741007194245, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=33.920704845815, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786783, Length=304, Percent_Identity=29.2763157894737, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790436, Length=212, Percent_Identity=34.4339622641509, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=37.5545851528384, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=30.0448430493274, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=26.7489711934156, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790300, Length=210, Percent_Identity=32.3809523809524, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=237, Percent_Identity=29.1139240506329, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788549, Length=276, Percent_Identity=28.6231884057971, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=288, Percent_Identity=28.8194444444444, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=27.8538812785388, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=24.7422680412371, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=29.957805907173, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=266, Percent_Identity=27.8195488721804, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790567, Length=201, Percent_Identity=30.8457711442786, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45653; Mature: 45653

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFRARLFLAFALLWLLFLGGAWYLAGRSVDQALKRRLEATLAQDALRAAEAYRKGQAG
CCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ALLTTGGVYLHLYAQDGTPLALTRPDHRLPPERLRRAGPTPEVLWEEGFAAALVATPLGL
EEEEECCEEEEEEECCCCEEEEECCCCCCCHHHHHHCCCCHHHHHHCCHHHHHHHCCHHH
LVLTAETSPIEAALEALREALLRAFLLLFPLGLALVYLTARLAARPLEAVAREITRRSPD
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
RLDPVPHRLPKDEFGRMVEAVNALLQALKEAKERERAFLAEASHELRTPLTVLLGHLDRL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRNPMDLEALRTARATAERMRRLVEDLLALARGEVERNLNLHIVDLGEVAREAALEYGVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCC
AEAESAEVLGDPDRLLQLLRNLVANAVRAAGKEGVRVRVRREADHALLEVEDSGPGIPED
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCHH
LLPRLFQRFARGPGGGTGLGLAIAHAIAKAHGGEIAVESRPGRTVFRVRLPLLEEEA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCHHCCCC
>Mature Secondary Structure
MLSFRARLFLAFALLWLLFLGGAWYLAGRSVDQALKRRLEATLAQDALRAAEAYRKGQAG
CCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ALLTTGGVYLHLYAQDGTPLALTRPDHRLPPERLRRAGPTPEVLWEEGFAAALVATPLGL
EEEEECCEEEEEEECCCCEEEEECCCCCCCHHHHHHCCCCHHHHHHCCHHHHHHHCCHHH
LVLTAETSPIEAALEALREALLRAFLLLFPLGLALVYLTARLAARPLEAVAREITRRSPD
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
RLDPVPHRLPKDEFGRMVEAVNALLQALKEAKERERAFLAEASHELRTPLTVLLGHLDRL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRNPMDLEALRTARATAERMRRLVEDLLALARGEVERNLNLHIVDLGEVAREAALEYGVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCC
AEAESAEVLGDPDRLLQLLRNLVANAVRAAGKEGVRVRVRREADHALLEVEDSGPGIPED
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCHH
LLPRLFQRFARGPGGGTGLGLAIAHAIAKAHGGEIAVESRPGRTVFRVRLPLLEEEA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]