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The map label for this gene is potC [H]

Identifier: 55981207

GI number: 55981207

Start: 1174264

End: 1175043

Strand: Reverse

Name: potC [H]

Synonym: TTHA1238

Alternate gene names: 55981207

Gene position: 1175043-1174264 (Counterclockwise)

Preceding gene: 55981208

Following gene: 55981206

Centisome position: 63.52

GC content: 66.54

Gene sequence:

>780_bases
ATGAGGCGGCTCCTCTCCTTCCACGCCCTTTTGGTCTACCTCTTCCTCTACCTGCCCATCCTCGTCGTCGTGGCCCTCTC
CTTCAACGAGAGCCGCAGGGGGGTCCACTTCACCGGCTTCACCCTGAAGTGGTACCAGGGCCTCTTCCAAGACCCAAGGG
TCCTGGAGTACTTCGCCAACACCCTGGTCGTGGCCCTGGTCTCCACCCTGGTCTCCACGGTCCTCGGGACCCTCCTCGCC
CTGGGCCTCGTGCGCTACCGCTTCCCCGGCAAAGGCTTCCTCCGCTACCTCCTCTACGTCCCCGTGGTGGTGCCCGACGT
GGTCATGGGGGTTTCCCTCCTCCTCCTCTTCGCCTTCTCCCGCGAGCTTTTGGGCTTTCCCCGGCTTTCCCTCCTCACGG
TGATCCTGGGGCACATCACCTTCCAGGTGGCCTTCGTGACCCTGGTGGTGCGCTCCCGGCTCCTCCTCCTGGACCCCGCC
CTGGAGGAGGCCGCCCGGGACCTGGGGGCGAGGGGGTTCCAGACCTTCCTCCACGTGACCCTTCCCCTGGCCTGGCCGGG
GGTGGCGGCGGGGGCGCTCCTCGCCCTCACCCTCTCCCTGGACGACTTCGTGGTCACCTTCTTCACCGCGGGGCCTGGGG
CCACCACCTTGCCCCTTTACATCTACTCCAGCGTGAAGCTCGGGGTGAGCCCCAAGGTCCACGCCCTCTCCAGCCTGATT
GTGGGGCTCAGCGCCTTCTTCCTCGCCCTGGGGTATGCTCTTAGCCGGAGGAGGTTATGA

Upstream 100 bases:

>100_bases
CCTTCGGGGCGGCCTTGAGCGTCTTCCTCATGGCCTTCGTCCTCTTAAGCCTCTACCTCTACGCCCGCCTCCAGGGGGAA
AGGGGGCTTGAGGACCTGGT

Downstream 100 bases:

>100_bases
GGCGGATTGCGGTGTTGCTCCTGCTCGTCGCGGTGGTGCTCCTCGGGTGGCTTTGGCTTCGGCCCAAGGCGCCTTCGGGC
GCGGGCACCCTTTACTTCCT

Product: spermidine/putrescine ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRRLLSFHALLVYLFLYLPILVVVALSFNESRRGVHFTGFTLKWYQGLFQDPRVLEYFANTLVVALVSTLVSTVLGTLLA
LGLVRYRFPGKGFLRYLLYVPVVVPDVVMGVSLLLLFAFSRELLGFPRLSLLTVILGHITFQVAFVTLVVRSRLLLLDPA
LEEAARDLGARGFQTFLHVTLPLAWPGVAAGALLALTLSLDDFVVTFFTAGPGATTLPLYIYSSVKLGVSPKVHALSSLI
VGLSAFFLALGYALSRRRL

Sequences:

>Translated_259_residues
MRRLLSFHALLVYLFLYLPILVVVALSFNESRRGVHFTGFTLKWYQGLFQDPRVLEYFANTLVVALVSTLVSTVLGTLLA
LGLVRYRFPGKGFLRYLLYVPVVVPDVVMGVSLLLLFAFSRELLGFPRLSLLTVILGHITFQVAFVTLVVRSRLLLLDPA
LEEAARDLGARGFQTFLHVTLPLAWPGVAAGALLALTLSLDDFVVTFFTAGPGATTLPLYIYSSVKLGVSPKVHALSSLI
VGLSAFFLALGYALSRRRL
>Mature_259_residues
MRRLLSFHALLVYLFLYLPILVVVALSFNESRRGVHFTGFTLKWYQGLFQDPRVLEYFANTLVVALVSTLVSTVLGTLLA
LGLVRYRFPGKGFLRYLLYVPVVVPDVVMGVSLLLLFAFSRELLGFPRLSLLTVILGHITFQVAFVTLVVRSRLLLLDPA
LEEAARDLGARGFQTFLHVTLPLAWPGVAAGALLALTLSLDDFVVTFFTAGPGATTLPLYIYSSVKLGVSPKVHALSSLI
VGLSAFFLALGYALSRRRL

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=232, Percent_Identity=43.5344827586207, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1787081, Length=235, Percent_Identity=42.9787234042553, Blast_Score=173, Evalue=8e-45,
Organism=Escherichia coli, GI1787714, Length=213, Percent_Identity=38.4976525821596, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788764, Length=174, Percent_Identity=35.632183908046, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787369, Length=212, Percent_Identity=31.6037735849057, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787713, Length=226, Percent_Identity=28.7610619469027, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28519; Mature: 28519

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLSFHALLVYLFLYLPILVVVALSFNESRRGVHFTGFTLKWYQGLFQDPRVLEYFAN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCCCHHHHHHHH
TLVVALVSTLVSTVLGTLLALGLVRYRFPGKGFLRYLLYVPVVVPDVVMGVSLLLLFAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELLGFPRLSLLTVILGHITFQVAFVTLVVRSRLLLLDPALEEAARDLGARGFQTFLHVT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHH
LPLAWPGVAAGALLALTLSLDDFVVTFFTAGPGATTLPLYIYSSVKLGVSPKVHALSSLI
HHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHEEEEEECCCCCHHHHHHHHH
VGLSAFFLALGYALSRRRL
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRLLSFHALLVYLFLYLPILVVVALSFNESRRGVHFTGFTLKWYQGLFQDPRVLEYFAN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCCCHHHHHHHH
TLVVALVSTLVSTVLGTLLALGLVRYRFPGKGFLRYLLYVPVVVPDVVMGVSLLLLFAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELLGFPRLSLLTVILGHITFQVAFVTLVVRSRLLLLDPALEEAARDLGARGFQTFLHVT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHH
LPLAWPGVAAGALLALTLSLDDFVVTFFTAGPGATTLPLYIYSSVKLGVSPKVHALSSLI
HHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHEEEEEECCCCCHHHHHHHHH
VGLSAFFLALGYALSRRRL
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]