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The map label for this gene is merR [H]

Identifier: 55981124

GI number: 55981124

Start: 1100198

End: 1100626

Strand: Reverse

Name: merR [H]

Synonym: TTHA1155

Alternate gene names: 55981124

Gene position: 1100626-1100198 (Counterclockwise)

Preceding gene: 55981125

Following gene: 55981123

Centisome position: 59.5

GC content: 70.4

Gene sequence:

>429_bases
ATGCCCTACACCATCGGCGAGCTCGCCCGGGCGTTTGGCCTTTCGCCTGATGCCCTCCGCTACTACGAAAGGCTTGGGCT
CCTCGCCCCCAGCGGCCGTTCGCCCGGGGGGTTTCGCCTCTACGGGGAGGAGGCCTTCCGCCGCCTCCGCTTCATCAAGG
AGGCCCAGGCGGCGGGGCTTAAGCTTGAGGACATCGCCTGGATCCTCCGCGCCGTGGAGGAGGGCCATCCCCCCTGCCGC
CACGTGCGGGAGGCCCTGGCCAAGCGCCTGGCGGAGGTGCGGCGTAGGCTCAGGGAGCTCCAGGCCCTGGAAGCGGCCCT
GGCCGAACGGCTGGCCTACGCCGAGGCCCACCCTGACCCTGCTTGCGACGGCAAGGACCGCTGCGTCTATTTGGACCCCC
TTGACCCTGGAGCACGCTCCAGGGTCTAG

Upstream 100 bases:

>100_bases
CCAGGCCGGGGTGACCCCAGGGCTCGTGCGGGTCTCCGTGGGCCTCGAGGACCCTCTGGACCTCCTCGCTCTCTTTGAGG
AGGCCCTGGAGGCGGTCTAG

Downstream 100 bases:

>100_bases
CCTGGGGGCATGGAGAAGAACCGGTACCGCATCAAGGTGCCCGGGATCCACGGCGCGGGGTGCATCCGCAGGGTGGAGCG
GGTGGCCGGGGTGGAGAAGG

Product: mercuric resistance operon regulatory protein MerR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MPYTIGELARAFGLSPDALRYYERLGLLAPSGRSPGGFRLYGEEAFRRLRFIKEAQAAGLKLEDIAWILRAVEEGHPPCR
HVREALAKRLAEVRRRLRELQALEAALAERLAYAEAHPDPACDGKDRCVYLDPLDPGARSRV

Sequences:

>Translated_142_residues
MPYTIGELARAFGLSPDALRYYERLGLLAPSGRSPGGFRLYGEEAFRRLRFIKEAQAAGLKLEDIAWILRAVEEGHPPCR
HVREALAKRLAEVRRRLRELQALEAALAERLAYAEAHPDPACDGKDRCVYLDPLDPGARSRV
>Mature_141_residues
PYTIGELARAFGLSPDALRYYERLGLLAPSGRSPGGFRLYGEEAFRRLRFIKEAQAAGLKLEDIAWILRAVEEGHPPCRH
VREALAKRLAEVRRRLRELQALEAALAERLAYAEAHPDPACDGKDRCVYLDPLDPGARSRV

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=140, Percent_Identity=36.4285714285714, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786695, Length=118, Percent_Identity=31.3559322033898, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15954; Mature: 15822

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYTIGELARAFGLSPDALRYYERLGLLAPSGRSPGGFRLYGEEAFRRLRFIKEAQAAGL
CCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCC
KLEDIAWILRAVEEGHPPCRHVREALAKRLAEVRRRLRELQALEAALAERLAYAEAHPDP
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ACDGKDRCVYLDPLDPGARSRV
CCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
PYTIGELARAFGLSPDALRYYERLGLLAPSGRSPGGFRLYGEEAFRRLRFIKEAQAAGL
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCC
KLEDIAWILRAVEEGHPPCRHVREALAKRLAEVRRRLRELQALEAALAERLAYAEAHPDP
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ACDGKDRCVYLDPLDPGARSRV
CCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400173 [H]