Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 55981115

GI number: 55981115

Start: 1091514

End: 1092464

Strand: Direct

Name: etfA [H]

Synonym: TTHA1146

Alternate gene names: 55981115

Gene position: 1091514-1092464 (Clockwise)

Preceding gene: 55981114

Following gene: 55981117

Centisome position: 59.01

GC content: 70.56

Gene sequence:

>951_bases
GTGCCTATGGTGCTCGTAGTCTTGGACCACGACGGAAACCGGCTCAAGAAGGGAAGCCTCGAGGCCCTGACCCGGGCCCG
TGACCTGGCCCAGGCCCTGGGGGGGAAGGTGGCCGGGGTGCTCCTCGCCGAGGAGAAGGCCCCCGTGGAGGAGGCCCGCA
AGTACGTGGAGGTTCTCTACACCGCCACCCTAGGCCCCTACACCGCCGAGAAGTGGGCGGCCGGGGTGCTTAAGGCCGCC
GAGGCCAGTGGGGCCAAGGCGGTGGTGGCCCCCTCCTCCAGGCAGAGCCGGGCCTACTTGGGCCGGGTGGCCTACGCCCT
AAGAGCGGGGCTTCTTGAGGACACCCTCGAGTCCCGCGTGGAAGGCGGCGAGGTCCACGCCACCCGCTACGCCTACCTGA
ACCGGGTGACCCAGAGGGTGAAGGCGGCCCTCCCCGTGGTCCTCACGGTGAAGCCCAACACCACCCCCTTGGCCGAGCCC
CTTCCGGGGGAGGCCGAGGCAGTGGCCCTAAGCGTGCCCGAGGTGCCCACGGTGGAGGTCCTGGAGCGCCTCCAGGAGGA
GAAGAAGGGCGTCTCCCTCACCGAGGCGGACGTGGTGGTCACGGGGGGCCGGGGGATGGGCAGCCCCGAGGCCTTCAAGC
TGGTGGAGGAGCTCGCCGCCCTCCTCGGGGGCGCGGTGGGGGCCACGCGGGCGGTGGTGGACGCGGGCTGGCGGCCCTAC
GCCGAGCAGGTGGGCCAGACGGGCAAGACCGTCCAGCCCTCCCTCTACATCGCCCTGGGGGTCTCCGGGGCCGTGCAGCA
CCTCGCGGGCATGAACAAGAGCAAGTACATCGTGGCCGTGAACAAGGACCCCGAGGCCCCCATCTTCAAGCACGCCGACT
ACGGCATCGTGGGGGACGTGCACCAGGTGCTCCCCGCCCTGATTGAGGCCGTGAAGAAGCTCAAGGACTGA

Upstream 100 bases:

>100_bases
GAAGTCCAGGCTTGGCAAGATCCTGGACGGCAAGGACCCCGTGGCGGCGGCCGAAGAGCTCGTGCGGCTCCTCCACGAGG
AGGCCAAGGTCATCTAGGAG

Downstream 100 bases:

>100_bases
GCCGAAGGTAAAGAACCCCCCGCCCAGAGGGCGGGGGGTTCTACACGCTTTTCGCCGGGGCCCCCATGCCGGCTTAGGCC
GGCATGGGGTGGGCTCACCC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPMVLVVLDHDGNRLKKGSLEALTRARDLAQALGGKVAGVLLAEEKAPVEEARKYVEVLYTATLGPYTAEKWAAGVLKAA
EASGAKAVVAPSSRQSRAYLGRVAYALRAGLLEDTLESRVEGGEVHATRYAYLNRVTQRVKAALPVVLTVKPNTTPLAEP
LPGEAEAVALSVPEVPTVEVLERLQEEKKGVSLTEADVVVTGGRGMGSPEAFKLVEELAALLGGAVGATRAVVDAGWRPY
AEQVGQTGKTVQPSLYIALGVSGAVQHLAGMNKSKYIVAVNKDPEAPIFKHADYGIVGDVHQVLPALIEAVKKLKD

Sequences:

>Translated_316_residues
MPMVLVVLDHDGNRLKKGSLEALTRARDLAQALGGKVAGVLLAEEKAPVEEARKYVEVLYTATLGPYTAEKWAAGVLKAA
EASGAKAVVAPSSRQSRAYLGRVAYALRAGLLEDTLESRVEGGEVHATRYAYLNRVTQRVKAALPVVLTVKPNTTPLAEP
LPGEAEAVALSVPEVPTVEVLERLQEEKKGVSLTEADVVVTGGRGMGSPEAFKLVEELAALLGGAVGATRAVVDAGWRPY
AEQVGQTGKTVQPSLYIALGVSGAVQHLAGMNKSKYIVAVNKDPEAPIFKHADYGIVGDVHQVLPALIEAVKKLKD
>Mature_315_residues
PMVLVVLDHDGNRLKKGSLEALTRARDLAQALGGKVAGVLLAEEKAPVEEARKYVEVLYTATLGPYTAEKWAAGVLKAAE
ASGAKAVVAPSSRQSRAYLGRVAYALRAGLLEDTLESRVEGGEVHATRYAYLNRVTQRVKAALPVVLTVKPNTTPLAEPL
PGEAEAVALSVPEVPTVEVLERLQEEKKGVSLTEADVVVTGGRGMGSPEAFKLVEELAALLGGAVGATRAVVDAGWRPYA
EQVGQTGKTVQPSLYIALGVSGAVQHLAGMNKSKYIVAVNKDPEAPIFKHADYGIVGDVHQVLPALIEAVKKLKD

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=121, Percent_Identity=64.4628099173554, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI189181759, Length=121, Percent_Identity=64.4628099173554, Blast_Score=155, Evalue=4e-38,
Organism=Escherichia coli, GI1786226, Length=231, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1787990, Length=232, Percent_Identity=33.1896551724138, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI87082157, Length=107, Percent_Identity=36.4485981308411, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=316, Percent_Identity=37.9746835443038, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6325261, Length=124, Percent_Identity=58.0645161290323, Blast_Score=142, Evalue=8e-35,
Organism=Drosophila melanogaster, GI17136898, Length=316, Percent_Identity=37.3417721518987, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24652801, Length=316, Percent_Identity=37.3417721518987, Blast_Score=160, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33354; Mature: 33223

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMVLVVLDHDGNRLKKGSLEALTRARDLAQALGGKVAGVLLAEEKAPVEEARKYVEVLY
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHHH
TATLGPYTAEKWAAGVLKAAEASGAKAVVAPSSRQSRAYLGRVAYALRAGLLEDTLESRV
HHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
EGGEVHATRYAYLNRVTQRVKAALPVVLTVKPNTTPLAEPLPGEAEAVALSVPEVPTVEV
CCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHH
LERLQEEKKGVSLTEADVVVTGGRGMGSPEAFKLVEELAALLGGAVGATRAVVDAGWRPY
HHHHHHHHCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
AEQVGQTGKTVQPSLYIALGVSGAVQHLAGMNKSKYIVAVNKDPEAPIFKHADYGIVGDV
HHHHCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCHHHH
HQVLPALIEAVKKLKD
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PMVLVVLDHDGNRLKKGSLEALTRARDLAQALGGKVAGVLLAEEKAPVEEARKYVEVLY
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHHH
TATLGPYTAEKWAAGVLKAAEASGAKAVVAPSSRQSRAYLGRVAYALRAGLLEDTLESRV
HHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
EGGEVHATRYAYLNRVTQRVKAALPVVLTVKPNTTPLAEPLPGEAEAVALSVPEVPTVEV
CCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHH
LERLQEEKKGVSLTEADVVVTGGRGMGSPEAFKLVEELAALLGGAVGATRAVVDAGWRPY
HHHHHHHHCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
AEQVGQTGKTVQPSLYIALGVSGAVQHLAGMNKSKYIVAVNKDPEAPIFKHADYGIVGDV
HHHHCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCHHHH
HQVLPALIEAVKKLKD
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]