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The map label for this gene is murB [H]

Identifier: 55981055

GI number: 55981055

Start: 1033453

End: 1034250

Strand: Direct

Name: murB [H]

Synonym: TTHA1086

Alternate gene names: 55981055

Gene position: 1033453-1034250 (Clockwise)

Preceding gene: 55981054

Following gene: 55981056

Centisome position: 55.87

GC content: 69.8

Gene sequence:

>798_bases
ATGAGGGTTGAACGGGTGCTGCTCAAGGACTACACCACCCTGGGGGTAGGGGGGCCGGCGGAGCTTTGGACCGTGGAGAC
CCGGGAGGAGCTCAAGCGGGCCACCGAGGCCCCTTACCGCGTCCTGGGCAACGGCTCCAACCTCCTCGTCCTGGACGAGG
GGGTGCCGGAGCGGGTCATCCGGCTTGCGGGCGAGTTCCAAACCTACGACCTGAAGGGCTGGGTGGGGGCGGGGACCCTC
CTTCCCCTCCTCGTCCAGGAGGCGGCCCGGGCGGGGCTTTCCGGCCTCGAGGGCCTCCTCGGCATCCCCGCCCAGGTGGG
CGGCGCGGTGAAGATGAACGCGGGCACCCGCTTCGGGGAGATGGCCGACGCCCTGGAGGCGGTGGAGGTCTTCCACGACG
GCGCCTTCCACGTCTACTGTCCGGAGGAGCTCGGCTTCGGCTACCGGAAAAGCCACCTCCCCCCCGGGGGCATCGTCACC
CGGGTGCGCCTCAAGCTGAAGGAGCGCCCCAAGGAGGAGATCCTGAGGCGCATGGCCGAGGTGGACCGGGCCCGCAAGGG
CCAGCCCAAGCGGAAAAGCGCCGGGTGCGCCTTCAAGAACCCCCCGGGCCAGTCGGCGGGACGGCTCATTGACGAGCGCG
GCCTCAAGGGGCTTCGGGTGGGGGACGCCATGATCTCCTTAGAGCACGGCAACTTCATCGTCAACCTGGGCCAGGCCCGG
GCAAAGGACGTCCTGGAGCTCGTCCGCCGGGTCCAGGAGGAGCTTCCCTTGGAGCTGGAGTGGGAGGTGTGGCCGTAA

Upstream 100 bases:

>100_bases
GAAGAGGCCCTGGCCTACGCCCGCGCCACGGCAAGGCCCGAGGACCTCCTCCTCTTCATGGGGGCCGGGGACGTGACCCT
TCTCGCGCGGAGGCTCGTCC

Downstream 100 bases:

>100_bases
AGGAGGGGTAAGATGGGCGTGGTGAAAGGCGTTCTCCTCCTCATCCTCGGGGCGAGCCTCTACGTGGCGAGCCTCGTGGC
CGTCCCCGTGGAGGAGGTGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTL
LPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVT
RVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQAR
AKDVLELVRRVQEELPLELEWEVWP

Sequences:

>Translated_265_residues
MRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTL
LPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVT
RVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQAR
AKDVLELVRRVQEELPLELEWEVWP
>Mature_265_residues
MRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTL
LPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVT
RVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQAR
AKDVLELVRRVQEELPLELEWEVWP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 29180; Mature: 29180

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVI
CCCHHHHHHCCCCCCCCCCHHEEEEHHHHHHHHHHCCCEEEECCCCCEEEECCCCHHHHH
RLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGE
HHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCHHCCCEEEECCCCCHHH
MADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAE
HHHHHHHHHHHHCCCEEEECHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
VDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQAR
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCCEEEECCHHH
AKDVLELVRRVQEELPLELEWEVWP
HHHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVI
CCCHHHHHHCCCCCCCCCCHHEEEEHHHHHHHHHHCCCEEEECCCCCEEEECCCCHHHHH
RLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGE
HHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCHHCCCEEEECCCCCHHH
MADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAE
HHHHHHHHHHHHCCCEEEECHHHHCCCCHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
VDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQAR
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCCEEEECCHHH
AKDVLELVRRVQEELPLELEWEVWP
HHHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA