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The map label for this gene is ribE [H]

Identifier: 55981032

GI number: 55981032

Start: 1009728

End: 1010312

Strand: Reverse

Name: ribE [H]

Synonym: TTHA1063

Alternate gene names: 55981032

Gene position: 1010312-1009728 (Counterclockwise)

Preceding gene: 55981033

Following gene: 55981031

Centisome position: 54.62

GC content: 69.4

Gene sequence:

>585_bases
ATGTTCACGGGACTCGTGGAGGAAACGGGGGAGATCCTGAAGGTGGAGGAAGGGCCCTTCCTCCGGGTCTACATAGGTGC
CCGGAAGGTGCTGGAGGACCTCAAGGTGGGGGACTCCGTGGCCGTGGACGGGGCCTGCCTCACGGCGGTGGCGGTGGAGG
AGGGGGGGTTTTGGGTGGAGCTCGCCCAGGAGACCCTGCGCCGCACCGCCCCCACCTGGCGGGTGGGGCACAGGCCCAAC
CTGGAGCGGGCCCTGAAGGTGGGGGACAGGCTTGGGGGGCACTTCGTCACCGGGCACGTGGACGGGGTGGCGAGGCTTTG
GGAGGTCCGCGAGGCCCCAGGGGCCAAGGACTTCTACTTCCTCCCCCCCAAGGCGCTCGCCCCCTACATCGCCGAGAAGG
GGAGCGTGGCCCTAAACGGGGTCTCCCTCACGGTGGCGGGGCTTACGGGGGAGGCCTTCTGGGTCACCCTCATCCCCCAC
ACCCTCGAGGTGACCAACCTGGGGAGGCTTCGGGTGGGGGACGGGGTGAACCTCGAGGTGGACCTCATCGCCCGTTACGT
GGCGCGGCTTTTGGGGAGAGCGTGA

Upstream 100 bases:

>100_bases
CTTTAGGGTGGAGCGGGTGGCGGAGGCCCTCCGCCTTCGCCTTGCCCGCAGGGAGTGGCTGGGGGAGAACCTCTGGCTCG
AGGCCTACCCGGAGGGATAG

Downstream 100 bases:

>100_bases
TGGAAGGGATCGCCAGCGTCAAGGAACTTCTGGAGGAGCTCAAGGCGGGCCGCCCCGTGATCTTGGTGGACGACGAGGAC
CGGGAGAACGAGGGCGACCT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MFTGLVEETGEILKVEEGPFLRVYIGARKVLEDLKVGDSVAVDGACLTAVAVEEGGFWVELAQETLRRTAPTWRVGHRPN
LERALKVGDRLGGHFVTGHVDGVARLWEVREAPGAKDFYFLPPKALAPYIAEKGSVALNGVSLTVAGLTGEAFWVTLIPH
TLEVTNLGRLRVGDGVNLEVDLIARYVARLLGRA

Sequences:

>Translated_194_residues
MFTGLVEETGEILKVEEGPFLRVYIGARKVLEDLKVGDSVAVDGACLTAVAVEEGGFWVELAQETLRRTAPTWRVGHRPN
LERALKVGDRLGGHFVTGHVDGVARLWEVREAPGAKDFYFLPPKALAPYIAEKGSVALNGVSLTVAGLTGEAFWVTLIPH
TLEVTNLGRLRVGDGVNLEVDLIARYVARLLGRA
>Mature_194_residues
MFTGLVEETGEILKVEEGPFLRVYIGARKVLEDLKVGDSVAVDGACLTAVAVEEGGFWVELAQETLRRTAPTWRVGHRPN
LERALKVGDRLGGHFVTGHVDGVARLWEVREAPGAKDFYFLPPKALAPYIAEKGSVALNGVSLTVAGLTGEAFWVTLIPH
TLEVTNLGRLRVGDGVNLEVDLIARYVARLLGRA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=36.2162162162162, Blast_Score=116, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=36.231884057971, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21028; Mature: 21028

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLVEETGEILKVEEGPFLRVYIGARKVLEDLKVGDSVAVDGACLTAVAVEEGGFWVE
CCCCCHHCCCCEEEECCCCEEEEEECHHHHHHHHCCCCCEEECCCEEEEEEEECCCEEHH
LAQETLRRTAPTWRVGHRPNLERALKVGDRLGGHFVTGHVDGVARLWEVREAPGAKDFYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCEEE
LPPKALAPYIAEKGSVALNGVSLTVAGLTGEAFWVTLIPHTLEVTNLGRLRVGDGVNLEV
ECHHHHHHHHHCCCCEEEECEEEEEEECCCCEEEEEECCCEEEEECCCEEEECCCCCEEH
DLIARYVARLLGRA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGLVEETGEILKVEEGPFLRVYIGARKVLEDLKVGDSVAVDGACLTAVAVEEGGFWVE
CCCCCHHCCCCEEEECCCCEEEEEECHHHHHHHHCCCCCEEECCCEEEEEEEECCCEEHH
LAQETLRRTAPTWRVGHRPNLERALKVGDRLGGHFVTGHVDGVARLWEVREAPGAKDFYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCEEE
LPPKALAPYIAEKGSVALNGVSLTVAGLTGEAFWVTLIPHTLEVTNLGRLRVGDGVNLEV
ECHHHHHHHHHCCCCEEEECEEEEEEECCCCEEEEEECCCEEEEECCCEEEECCCCCEEH
DLIARYVARLLGRA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]