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The map label for this gene is macB [H]

Identifier: 55980977

GI number: 55980977

Start: 954496

End: 955755

Strand: Direct

Name: macB [H]

Synonym: TTHA1008

Alternate gene names: 55980977

Gene position: 954496-955755 (Clockwise)

Preceding gene: 55980976

Following gene: 55980978

Centisome position: 51.6

GC content: 70.32

Gene sequence:

>1260_bases
ATGGCTGAGGAAAAACACGTCGGGCTCAGCCTCGCAGAGACGCTCCGCATCGCCTGGAAGGCGATCGCCGCAAACCCCCT
TCGCTCCGCCCTGACCGCCCTCGGCGTGATCATCGGCGTGGCGGCGGTCGTGGCCCTCACCATGGTGGGCCAGGGGACGA
CGCGAAACGTCACCCAGCTCCTGGAGGGCCTCGGGACAAACCTCCTCACCGTGGGGCCGGCCCAGGGGAGCCGGGGCCCG
GGAGGCGGCCTGGTGCGGGCAGGGGGTCCCGAGACCATCCCCCTCTCCGACGCCTACGCCATCCAGGAGGCCTTCGCCGA
GGAGGTGGTGGGCGTGGCCCCGGTGGCCCAGGAGCGGTTCCAGATCCGCAGTGGGAGCACGAACTTCCAGGCCACGGTGG
TGGGCACCTGGCCGGACTTCGCCAAGGTGCGGAACGCCGAGCCCGAGAAGGGGAGCTTCTTCACCTGGGACGACGTGACC
GCCAAACGGCGGGTCGCCGTCCTCGGCTACGGCGTCGCCGAGGACCTCTTCGGAACCGACGACCCCCTGGGGCAGCGGAT
CCGGATCAACGGGATCCCGTTCACCGTCATCGGCGTCCTCCCGGACAAGGGGGACCAGGGCTTCGTCAGCACGAACTACC
AGGTCTTCGTGCCGCTTTCCACCTACCTGCAACGCCTCGCCAGGCCCGAGGCCGGGGAAGCCAAGGTGAACACGATCTAC
CTCCAGGGCGCAAGCCGCGACCGGCTCAAGGACCTGCAGGAACGGCTCACCCGCTTCCTCGCCGAGCGCCACGGCCTGAC
CGACCCAAACGACTACGACTTCTCCGTCGCGAACCAGCAGGACGCCCTGGAGAGCGTGAACGCCACGACGAGGACCCTCA
CCCTCTTCCTCGGGGGGGTCGCGGCGATCAGCCTCCTCGTCGGAGGGATCGGGATCATGAACATCATGCTCGTCTCGGTC
ACCGAGCGGACGCGGGAGATCGGCGTGCGCAAGGCCCTGGGGGCGCGGCCCCGGGACATCCTGGCCCAGTTCCTCGCCGA
GTCCGTCGTCCTCTCGGTCGGCGGGGGCACGCTCGGCGTCGTGCTGGGCCTGGGCCTCGCCGGGGCCGTGGGGCGGGCGC
TCACGGTCACCCCGGTCTTCTCGCCGGGAAGCGCAGCCGTGGCCTTCTTCTTCGCGGTCCTCGTCGGGATCTTCTTCGGC
CTCTACCCCGCGTGGCGGGCCGCCCGTCTGGACCCCGTGGAGGCCCTGCGCTATGAGTGA

Upstream 100 bases:

>100_bases
ACGGTGATCTTGGTAACCCACGAGCCCCACGTGGCCGAGAAGACGAACCGGATCGTCCGGGTCCTGGACGGGGAGATCGT
CGCCGACGAAAGGAGGCACC

Downstream 100 bases:

>100_bases
CGCCCTTTCTCCCGGGCCCGGATGACCCAAAAGAAGCCCCCAGGGAACCTCTTGCCGGGGCCCCATGCCGGCGCAGGTCG
GCATGGGGTGGCCTCACCCG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MAEEKHVGLSLAETLRIAWKAIAANPLRSALTALGVIIGVAAVVALTMVGQGTTRNVTQLLEGLGTNLLTVGPAQGSRGP
GGGLVRAGGPETIPLSDAYAIQEAFAEEVVGVAPVAQERFQIRSGSTNFQATVVGTWPDFAKVRNAEPEKGSFFTWDDVT
AKRRVAVLGYGVAEDLFGTDDPLGQRIRINGIPFTVIGVLPDKGDQGFVSTNYQVFVPLSTYLQRLARPEAGEAKVNTIY
LQGASRDRLKDLQERLTRFLAERHGLTDPNDYDFSVANQQDALESVNATTRTLTLFLGGVAAISLLVGGIGIMNIMLVSV
TERTREIGVRKALGARPRDILAQFLAESVVLSVGGGTLGVVLGLGLAGAVGRALTVTPVFSPGSAAVAFFFAVLVGIFFG
LYPAWRAARLDPVEALRYE

Sequences:

>Translated_419_residues
MAEEKHVGLSLAETLRIAWKAIAANPLRSALTALGVIIGVAAVVALTMVGQGTTRNVTQLLEGLGTNLLTVGPAQGSRGP
GGGLVRAGGPETIPLSDAYAIQEAFAEEVVGVAPVAQERFQIRSGSTNFQATVVGTWPDFAKVRNAEPEKGSFFTWDDVT
AKRRVAVLGYGVAEDLFGTDDPLGQRIRINGIPFTVIGVLPDKGDQGFVSTNYQVFVPLSTYLQRLARPEAGEAKVNTIY
LQGASRDRLKDLQERLTRFLAERHGLTDPNDYDFSVANQQDALESVNATTRTLTLFLGGVAAISLLVGGIGIMNIMLVSV
TERTREIGVRKALGARPRDILAQFLAESVVLSVGGGTLGVVLGLGLAGAVGRALTVTPVFSPGSAAVAFFFAVLVGIFFG
LYPAWRAARLDPVEALRYE
>Mature_418_residues
AEEKHVGLSLAETLRIAWKAIAANPLRSALTALGVIIGVAAVVALTMVGQGTTRNVTQLLEGLGTNLLTVGPAQGSRGPG
GGLVRAGGPETIPLSDAYAIQEAFAEEVVGVAPVAQERFQIRSGSTNFQATVVGTWPDFAKVRNAEPEKGSFFTWDDVTA
KRRVAVLGYGVAEDLFGTDDPLGQRIRINGIPFTVIGVLPDKGDQGFVSTNYQVFVPLSTYLQRLARPEAGEAKVNTIYL
QGASRDRLKDLQERLTRFLAERHGLTDPNDYDFSVANQQDALESVNATTRTLTLFLGGVAAISLLVGGIGIMNIMLVSVT
ERTREIGVRKALGARPRDILAQFLAESVVLSVGGGTLGVVLGLGLAGAVGRALTVTPVFSPGSAAVAFFFAVLVGIFFGL
YPAWRAARLDPVEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=411, Percent_Identity=36.9829683698297, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44379; Mature: 44247

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEKHVGLSLAETLRIAWKAIAANPLRSALTALGVIIGVAAVVALTMVGQGTTRNVTQL
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LEGLGTNLLTVGPAQGSRGPGGGLVRAGGPETIPLSDAYAIQEAFAEEVVGVAPVAQERF
HHHCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
QIRSGSTNFQATVVGTWPDFAKVRNAEPEKGSFFTWDDVTAKRRVAVLGYGVAEDLFGTD
HHCCCCCCEEEEEEECCCCHHHHCCCCCCCCCEEEECCCCHHCEEEEEECCHHHHHCCCC
DPLGQRIRINGIPFTVIGVLPDKGDQGFVSTNYQVFVPLSTYLQRLARPEAGEAKVNTIY
CCCCCEEEECCCCEEEEEEECCCCCCCEEECCCEEEEEHHHHHHHHCCCCCCCCEEEEEE
LQGASRDRLKDLQERLTRFLAERHGLTDPNDYDFSVANQQDALESVNATTRTLTLFLGGV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHH
AAISLLVGGIGIMNIMLVSVTERTREIGVRKALGARPRDILAQFLAESVVLSVGGGTLGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCHHHH
VLGLGLAGAVGRALTVTPVFSPGSAAVAFFFAVLVGIFFGLYPAWRAARLDPVEALRYE
HHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
AEEKHVGLSLAETLRIAWKAIAANPLRSALTALGVIIGVAAVVALTMVGQGTTRNVTQL
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LEGLGTNLLTVGPAQGSRGPGGGLVRAGGPETIPLSDAYAIQEAFAEEVVGVAPVAQERF
HHHCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
QIRSGSTNFQATVVGTWPDFAKVRNAEPEKGSFFTWDDVTAKRRVAVLGYGVAEDLFGTD
HHCCCCCCEEEEEEECCCCHHHHCCCCCCCCCEEEECCCCHHCEEEEEECCHHHHHCCCC
DPLGQRIRINGIPFTVIGVLPDKGDQGFVSTNYQVFVPLSTYLQRLARPEAGEAKVNTIY
CCCCCEEEECCCCEEEEEEECCCCCCCEEECCCEEEEEHHHHHHHHCCCCCCCCEEEEEE
LQGASRDRLKDLQERLTRFLAERHGLTDPNDYDFSVANQQDALESVNATTRTLTLFLGGV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHH
AAISLLVGGIGIMNIMLVSVTERTREIGVRKALGARPRDILAQFLAESVVLSVGGGTLGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCHHHH
VLGLGLAGAVGRALTVTPVFSPGSAAVAFFFAVLVGIFFGLYPAWRAARLDPVEALRYE
HHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA