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The map label for this gene is bphC [H]

Identifier: 55980931

GI number: 55980931

Start: 908147

End: 909106

Strand: Direct

Name: bphC [H]

Synonym: TTHA0962

Alternate gene names: 55980931

Gene position: 908147-909106 (Clockwise)

Preceding gene: 55980930

Following gene: 55980932

Centisome position: 49.1

GC content: 67.71

Gene sequence:

>960_bases
ATGGCCATCGTGAGGGTGGGGTTTGTGGAACTTTGGGTGCGGGACCTGGAGAAGAGCCTGGAGTTCTACCAGGGGCTTCT
GGGCTTCCGCCTGGAGCACCGGGAGAAGAAGGCGGCCTACCTCCGGGGCTACGAGGAGCTGGAGTGGAGCCTCAAGCTCA
CCGAGGCCCCCTTCCCCGCGGTGCGCGCCCTGGGCTTCAAGGTGGACTCGGAAGAGGGCGTCCGGGCCCTCCAGGACCTC
GCCGCCAAGGAGGGGTGGCCCCACCGCCTCGAGGCGGACTGGGGAAGGCCCGAGGTCCTGAAGGTGCAGGACCCCTTCGG
CTACCCTCTGGCCTTCTACTTCAAGGCGGAGAAGCTTCCCCGGGTCCTTCAGCGCTACCACGAGTACAGGGGGCCCGGGA
TCCTGCGCATAGACCACCTCAACGTCTTCTCCCCCGCGGTGGGGGAGGCCACGCGGTTCTACCAGGAGGTCTTCGGCTTC
CGCCTCACGGAGTACACGGAGGACGACGAGGGGAGGCTTTGGGCGAGCTGGCTCCACCGTAAGGGCAACGTTCACGATAT
CGCCTTCACCAACGGGGAAGGCCCCAGGCTCCACCACTTCGCCTACTGGCTTCCCGACCCCCTCGCCGTGCTGAAGGCGG
CGGACATCCTGGCGGGGGCCATGCGCACCGACCAGATTGAGCGGGGCCCCGGGCGGCACGGGATCTCCAACGCCATGTTC
CTCTACCTCAAAGACCCCGACGGACACCGCATAGAGCTCTACACCTCCGACTACCTCACCGTGGACCCCGACCACCCCCC
GGTGCGCTGGAGCCTGAACGACCCCCGCCGCCAGACCCTCTGGGGGCACCGCACGCCCAAGAGCTGGTTCCTGGAGGGGA
GCGTACTGCTGGACCTCGAGGAAAACCCCGTGCCCACGCGCCCCTCGGTCCTGCAGGGCCTCCCCGAGCACGTGACTTGA

Upstream 100 bases:

>100_bases
GGGGGGACCACCGGATCGTGGTGGGCCTGGTGGAGGAGGTGGAGCTCGGGGAGGAGGGGCCTCCTTTGGTCTACTTCCAA
AGGGGCTACAGGAGGTTGGT

Downstream 100 bases:

>100_bases
CGGGAAAAAGGTCCCTTCCTAGACTGGGAGGCGAACCGAACGGCCGTTAGTTTGGTCCAAACCGGGCAAGCCCGGTGCGG
AGAAAAGGAGGGTCAAGATG

Product: homoprotocatechuate 2,3-dioxygenase

Products: NA

Alternate protein names: Mn(II)-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase; Mn(II)-dependent 23OHBP oxygenase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAIVRVGFVELWVRDLEKSLEFYQGLLGFRLEHREKKAAYLRGYEELEWSLKLTEAPFPAVRALGFKVDSEEGVRALQDL
AAKEGWPHRLEADWGRPEVLKVQDPFGYPLAFYFKAEKLPRVLQRYHEYRGPGILRIDHLNVFSPAVGEATRFYQEVFGF
RLTEYTEDDEGRLWASWLHRKGNVHDIAFTNGEGPRLHHFAYWLPDPLAVLKAADILAGAMRTDQIERGPGRHGISNAMF
LYLKDPDGHRIELYTSDYLTVDPDHPPVRWSLNDPRRQTLWGHRTPKSWFLEGSVLLDLEENPVPTRPSVLQGLPEHVT

Sequences:

>Translated_319_residues
MAIVRVGFVELWVRDLEKSLEFYQGLLGFRLEHREKKAAYLRGYEELEWSLKLTEAPFPAVRALGFKVDSEEGVRALQDL
AAKEGWPHRLEADWGRPEVLKVQDPFGYPLAFYFKAEKLPRVLQRYHEYRGPGILRIDHLNVFSPAVGEATRFYQEVFGF
RLTEYTEDDEGRLWASWLHRKGNVHDIAFTNGEGPRLHHFAYWLPDPLAVLKAADILAGAMRTDQIERGPGRHGISNAMF
LYLKDPDGHRIELYTSDYLTVDPDHPPVRWSLNDPRRQTLWGHRTPKSWFLEGSVLLDLEENPVPTRPSVLQGLPEHVT
>Mature_318_residues
AIVRVGFVELWVRDLEKSLEFYQGLLGFRLEHREKKAAYLRGYEELEWSLKLTEAPFPAVRALGFKVDSEEGVRALQDLA
AKEGWPHRLEADWGRPEVLKVQDPFGYPLAFYFKAEKLPRVLQRYHEYRGPGILRIDHLNVFSPAVGEATRFYQEVFGFR
LTEYTEDDEGRLWASWLHRKGNVHDIAFTNGEGPRLHHFAYWLPDPLAVLKAADILAGAMRTDQIERGPGRHGISNAMFL
YLKDPDGHRIELYTSDYLTVDPDHPPVRWSLNDPRRQTLWGHRTPKSWFLEGSVLLDLEENPVPTRPSVLQGLPEHVT

Specific function: Catalyzes the meta-cleavage of the hydroxylated biphenyl ring. The enzyme can oxidize a wide range of substrates, and the substrate preference order is 2,3-dihydroxybiphenyl > 3- methylcatechol > catechol > 4-methylcatechol > 4-chlorocatechol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.39 [H]

Molecular weight: Translated: 36907; Mature: 36776

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00082 EXTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVRVGFVELWVRDLEKSLEFYQGLLGFRLEHREKKAAYLRGYEELEWSLKLTEAPFPA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCHH
VRALGFKVDSEEGVRALQDLAAKEGWPHRLEADWGRPEVLKVQDPFGYPLAFYFKAEKLP
HHHHCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEHHHHH
RVLQRYHEYRGPGILRIDHLNVFSPAVGEATRFYQEVFGFRLTEYTEDDEGRLWASWLHR
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHC
KGNVHDIAFTNGEGPRLHHFAYWLPDPLAVLKAADILAGAMRTDQIERGPGRHGISNAMF
CCCEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LYLKDPDGHRIELYTSDYLTVDPDHPPVRWSLNDPRRQTLWGHRTPKSWFLEGSVLLDLE
EEEECCCCCEEEEEECCEEEECCCCCCEEECCCCCHHHHHCCCCCCCCEEEECEEEEEEC
ENPVPTRPSVLQGLPEHVT
CCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
AIVRVGFVELWVRDLEKSLEFYQGLLGFRLEHREKKAAYLRGYEELEWSLKLTEAPFPA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCHH
VRALGFKVDSEEGVRALQDLAAKEGWPHRLEADWGRPEVLKVQDPFGYPLAFYFKAEKLP
HHHHCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEHHHHH
RVLQRYHEYRGPGILRIDHLNVFSPAVGEATRFYQEVFGFRLTEYTEDDEGRLWASWLHR
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHC
KGNVHDIAFTNGEGPRLHHFAYWLPDPLAVLKAADILAGAMRTDQIERGPGRHGISNAMF
CCCEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LYLKDPDGHRIELYTSDYLTVDPDHPPVRWSLNDPRRQTLWGHRTPKSWFLEGSVLLDLE
EEEECCCCCEEEEEECCEEEECCCCCCEEECCCCCHHHHHCCCCCCCCEEEECEEEEEEC
ENPVPTRPSVLQGLPEHVT
CCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12672826 [H]