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The map label for this gene is des [H]

Identifier: 55980917

GI number: 55980917

Start: 894038

End: 895075

Strand: Reverse

Name: des [H]

Synonym: TTHA0948

Alternate gene names: 55980917

Gene position: 895075-894038 (Counterclockwise)

Preceding gene: 55980918

Following gene: 55980916

Centisome position: 48.39

GC content: 63.58

Gene sequence:

>1038_bases
ATGGAAAAGATTCAACCCAAAGACTGGATTCCCCTTATCAAGCCCTACACCAAGCCCAGCGTGGCCCGGAGCCTCCGCCA
GGTGGCCGACACCCTCCTTCCCCTCCTCGCCCTCTTCTACCTCGCCCACAAGGCCCTCTCCGTCTCCCTCCTCCTCGCCC
TGGCCCTGGACTTCGTCGCGGCTCTCTTCCTGGTGCGCCTCTTCATCCTCCAGCACGACGCCGGGCACGGCTCCTTCTTC
CCCAAGAAGTGGATGAACGACCTCCTGGGCTTCTTCGCCGGGGTCCTCACCCTGGTGCCCTACCACCACTGGCAGCTCTC
CCACGCCCGCCACCACGCCACGAGCGGCAACCTGGACAAGCGGGGCGTGGGGGACATCTACACCATGACCCTGGAGGAGT
ACCTGAAGGCCACCCCTGGGGAAAGGCTTAGGTACCGTCTCTACCGCAACCCCTTCGTCATGTTCTTCCTGGGGCCCATC
TACGTCTTCATGCTCTCCTACCGCCTGCCCTTGGGCTACGGCTCGGAAAAGCCCTCGGTGCGCAACTCCGTGGCCCTCAC
CAACCTCTTCCTGGTCCTGCTTTGGACGGGCATCTACCTCGGCTTCGGCCTCAAGACCCTTCTCCTCGTCTACCTCCCCA
TCCAGTACTTCGCCGGTATGGTGGGCATCTTCCTCTTCTACGTGCAACACCAGTTTGAGGACGCCTACTGGGAGCACGAC
CCCCGCTGGGAGCACCTCAAGGCCGCCATGGAGGGGAGCACCTACCTCAAGCTCCCCAGGGTCCTGCAGTGGCTCACCGG
GAACATCGGCTTCCACCACATCCACCACCTGGCCCCCAAGATCCCCAACTACCTCCTCCCCGAGGTGCAGGAGAAGGTGG
ACCTGGTGAAGGTGGCCCCCACCGTGACCCTCAAGGACGCCTTTCGCATCGCCTTCGCCGACATGCACCTCCACGACGAA
AAGCGCCGCAAACTCGTGGGCTTCAAGGAGGCCCACCGCCTTCTGCGGGAGGGAAGCGCCGCCCACGAGGGTGTATAA

Upstream 100 bases:

>100_bases
TCGGAGGAACGCTTCCGCCCACGCTGAGGGGCGCCGTTTGACCTTTGCCCCCGTTACCGGGTAAACTAGCAGGAACGCCC
CACTCGGCGTGGAGTAAAAG

Downstream 100 bases:

>100_bases
AAGAAGGCATGCGGCGCGTCTTGGTGGCGGGCAACTGGAAAATGCACAAAACGCCCTCCGAGGCCAGGGTGTGGTTCGCC
GAGCTCAAGAGGCTCCTTCC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MEKIQPKDWIPLIKPYTKPSVARSLRQVADTLLPLLALFYLAHKALSVSLLLALALDFVAALFLVRLFILQHDAGHGSFF
PKKWMNDLLGFFAGVLTLVPYHHWQLSHARHHATSGNLDKRGVGDIYTMTLEEYLKATPGERLRYRLYRNPFVMFFLGPI
YVFMLSYRLPLGYGSEKPSVRNSVALTNLFLVLLWTGIYLGFGLKTLLLVYLPIQYFAGMVGIFLFYVQHQFEDAYWEHD
PRWEHLKAAMEGSTYLKLPRVLQWLTGNIGFHHIHHLAPKIPNYLLPEVQEKVDLVKVAPTVTLKDAFRIAFADMHLHDE
KRRKLVGFKEAHRLLREGSAAHEGV

Sequences:

>Translated_345_residues
MEKIQPKDWIPLIKPYTKPSVARSLRQVADTLLPLLALFYLAHKALSVSLLLALALDFVAALFLVRLFILQHDAGHGSFF
PKKWMNDLLGFFAGVLTLVPYHHWQLSHARHHATSGNLDKRGVGDIYTMTLEEYLKATPGERLRYRLYRNPFVMFFLGPI
YVFMLSYRLPLGYGSEKPSVRNSVALTNLFLVLLWTGIYLGFGLKTLLLVYLPIQYFAGMVGIFLFYVQHQFEDAYWEHD
PRWEHLKAAMEGSTYLKLPRVLQWLTGNIGFHHIHHLAPKIPNYLLPEVQEKVDLVKVAPTVTLKDAFRIAFADMHLHDE
KRRKLVGFKEAHRLLREGSAAHEGV
>Mature_345_residues
MEKIQPKDWIPLIKPYTKPSVARSLRQVADTLLPLLALFYLAHKALSVSLLLALALDFVAALFLVRLFILQHDAGHGSFF
PKKWMNDLLGFFAGVLTLVPYHHWQLSHARHHATSGNLDKRGVGDIYTMTLEEYLKATPGERLRYRLYRNPFVMFFLGPI
YVFMLSYRLPLGYGSEKPSVRNSVALTNLFLVLLWTGIYLGFGLKTLLLVYLPIQYFAGMVGIFLFYVQHQFEDAYWEHD
PRWEHLKAAMEGSTYLKLPRVLQWLTGNIGFHHIHHLAPKIPNYLLPEVQEKVDLVKVAPTVTLKDAFRIAFADMHLHDE
KRRKLVGFKEAHRLLREGSAAHEGV

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 39729; Mature: 39729

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIQPKDWIPLIKPYTKPSVARSLRQVADTLLPLLALFYLAHKALSVSLLLALALDFVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFLVRLFILQHDAGHGSFFPKKWMNDLLGFFAGVLTLVPYHHWQLSHARHHATSGNLDK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGVGDIYTMTLEEYLKATPGERLRYRLYRNPFVMFFLGPIYVFMLSYRLPLGYGSEKPSV
CCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
RNSVALTNLFLVLLWTGIYLGFGLKTLLLVYLPIQYFAGMVGIFLFYVQHQFEDAYWEHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRWEHLKAAMEGSTYLKLPRVLQWLTGNIGFHHIHHLAPKIPNYLLPEVQEKVDLVKVAP
CCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
TVTLKDAFRIAFADMHLHDEKRRKLVGFKEAHRLLREGSAAHEGV
CEEHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEKIQPKDWIPLIKPYTKPSVARSLRQVADTLLPLLALFYLAHKALSVSLLLALALDFVA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFLVRLFILQHDAGHGSFFPKKWMNDLLGFFAGVLTLVPYHHWQLSHARHHATSGNLDK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGVGDIYTMTLEEYLKATPGERLRYRLYRNPFVMFFLGPIYVFMLSYRLPLGYGSEKPSV
CCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
RNSVALTNLFLVLLWTGIYLGFGLKTLLLVYLPIQYFAGMVGIFLFYVQHQFEDAYWEHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRWEHLKAAMEGSTYLKLPRVLQWLTGNIGFHHIHHLAPKIPNYLLPEVQEKVDLVKVAP
CCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
TVTLKDAFRIAFADMHLHDEKRRKLVGFKEAHRLLREGSAAHEGV
CEEHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]