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The map label for this gene is ahpF [C]

Identifier: 55980807

GI number: 55980807

Start: 803788

End: 804477

Strand: Direct

Name: ahpF [C]

Synonym: TTHA0838

Alternate gene names: 55980807

Gene position: 803788-804477 (Clockwise)

Preceding gene: 55980802

Following gene: 55980808

Centisome position: 43.45

GC content: 67.1

Gene sequence:

>690_bases
ATGGCGCTTTTGGGACCCAAAGAGCAAGAGATCGTGCGGGAAAGGCTGGCCAACCTCACCCGGGACGTGGAGATGGTGCT
CTTCACCGACTCCTCCACCTTGATCGCCCCGGGGAAGGAGCCCTGCCTCTACTGCAAGGAGACGAAGCAGCTTCTGGAGG
AGCTTTCCGCCCTCTCCGACAAGCTCCACCTGGTGGTCTACGACCTGGCCACCCCCGAGGGGAGGGAGAAGGCCGGGGCC
TACAAGGTGGAGGCCGCGCCCACCCTTATCCTTCGCGAGAAGGGTTCGGAGGCCATCAACCTCCGTTACCGGGGGATCCC
CGCGGGCTACGAGTTCGCGAGCCTCCTCGAGGACATCGAGATGCTGGGCCGGGATGGGCACGGCCTCCCTGAGAACGTGG
TCCAGGAGCTCAACGACCTCCCCGAGGAGGTGGTCCTCCAGGTCTTCGTCACCCCCACCTGCCCCTACTGCCCGCAGGCG
GTGCGCACCGCCCACCGCCTGGCCTACGCCTCCCCCAAGGTGTGGGGCGAGATGATTGAGGCCAACGAGTTCCCCGCCCT
CTCCGACCGCTACCGCATCCACGGCGTGCCGGACACCATCATCAACCACGGCAAGGAGCGCGTCCTCGGGGCCCAGCCCC
TCTCCCAGTTCCTCCAGGCCATCCGGAAGGCCGTGGGGGTCCGGGCCTAG

Upstream 100 bases:

>100_bases
CAAGCCGCGGGAACGTGAAAGTGCGCTCTTTCCTCGGGGCTCTTTATCTGGTATAGTTAGGGCCTGGACGTACCCCTACC
GGGGTATTCCGGAGGTGAAC

Downstream 100 bases:

>100_bases
CATGACCCGCCGCGCCCTCTTCGGCCCCAAGGTCGCTCCGCTGATCCAGGCGGCCTCGCTGACCCTCGCCCTCCTCCTCT
TCCTCGCCGCCTGCGGCCCC

Product: glutaredoxin-like protein

Products: an alcohol; H2O; NAD [C]

Alternate protein names: Glutaredoxin-Like Domain-Containing Protein; Glutaredoxin-Like Protein; Alkyl Hydroperoxide Reductase F Subunit; Thioredoxin Reductase; FAD-Dependent Pyridine Nucleotide-Disulphide Oxidoreductase; Protein-Disulfide Oxidoreductase; Glutaredoxin-Related Protein; Protein Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase Large Subunit; Thioredoxin Reductase/Glutathione-Related Protein; NADH Dehydrogenase; Thioredoxin Reductase-Like Protein; Redoxin-Like Protein; Alkyl Hydroperoxide Reductase Subunit F Related Protein; Alkyl Hydroperoxide Reductase Subunit F; AhpF Family Protein/Thioredoxin Reductase; Dehydrogenase Selenocysteine-Containing; Dehydrogenase Selenocysteine-Containing Protein; Thioredoxin-Disulfide Reductase; Alkyl Hydroperoxide Reductase Subunit; Glutaredoxin Related Protein; Thioredoxin Reductase/Glutathione-Like Protein

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MALLGPKEQEIVRERLANLTRDVEMVLFTDSSTLIAPGKEPCLYCKETKQLLEELSALSDKLHLVVYDLATPEGREKAGA
YKVEAAPTLILREKGSEAINLRYRGIPAGYEFASLLEDIEMLGRDGHGLPENVVQELNDLPEEVVLQVFVTPTCPYCPQA
VRTAHRLAYASPKVWGEMIEANEFPALSDRYRIHGVPDTIINHGKERVLGAQPLSQFLQAIRKAVGVRA

Sequences:

>Translated_229_residues
MALLGPKEQEIVRERLANLTRDVEMVLFTDSSTLIAPGKEPCLYCKETKQLLEELSALSDKLHLVVYDLATPEGREKAGA
YKVEAAPTLILREKGSEAINLRYRGIPAGYEFASLLEDIEMLGRDGHGLPENVVQELNDLPEEVVLQVFVTPTCPYCPQA
VRTAHRLAYASPKVWGEMIEANEFPALSDRYRIHGVPDTIINHGKERVLGAQPLSQFLQAIRKAVGVRA
>Mature_228_residues
ALLGPKEQEIVRERLANLTRDVEMVLFTDSSTLIAPGKEPCLYCKETKQLLEELSALSDKLHLVVYDLATPEGREKAGAY
KVEAAPTLILREKGSEAINLRYRGIPAGYEFASLLEDIEMLGRDGHGLPENVVQELNDLPEEVVLQVFVTPTCPYCPQAV
RTAHRLAYASPKVWGEMIEANEFPALSDRYRIHGVPDTIINHGKERVLGAQPLSQFLQAIRKAVGVRA

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.4.- [C]

Molecular weight: Translated: 25448; Mature: 25316

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLGPKEQEIVRERLANLTRDVEMVLFTDSSTLIAPGKEPCLYCKETKQLLEELSALSD
CCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCEEECCCCCCCEEHHHHHHHHHHHHHHHH
KLHLVVYDLATPEGREKAGAYKVEAAPTLILREKGSEAINLRYRGIPAGYEFASLLEDIE
HHEEEEEECCCCCCCHHCCCEEECCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHH
MLGRDGHGLPENVVQELNDLPEEVVLQVFVTPTCPYCPQAVRTAHRLAYASPKVWGEMIE
HHCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
ANEFPALSDRYRIHGVPDTIINHGKERVLGAQPLSQFLQAIRKAVGVRA
CCCCCCCCCCCEECCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALLGPKEQEIVRERLANLTRDVEMVLFTDSSTLIAPGKEPCLYCKETKQLLEELSALSD
CCCCCCHHHHHHHHHHHHHHCEEEEEEECCCEEECCCCCCCEEHHHHHHHHHHHHHHHH
KLHLVVYDLATPEGREKAGAYKVEAAPTLILREKGSEAINLRYRGIPAGYEFASLLEDIE
HHEEEEEECCCCCCCHHCCCEEECCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHH
MLGRDGHGLPENVVQELNDLPEEVVLQVFVTPTCPYCPQAVRTAHRLAYASPKVWGEMIE
HHCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
ANEFPALSDRYRIHGVPDTIINHGKERVLGAQPLSQFLQAIRKAVGVRA
CCCCCCCCCCCEECCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ROOH; Proton; NADH [C]

Specific reaction: ROOH + Proton + NADH = an alcohol + H2O + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA