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The map label for this gene is glcD [H]

Identifier: 55980766

GI number: 55980766

Start: 761564

End: 762919

Strand: Direct

Name: glcD [H]

Synonym: TTHA0797

Alternate gene names: 55980766

Gene position: 761564-762919 (Clockwise)

Preceding gene: 55980765

Following gene: 55980767

Centisome position: 41.17

GC content: 73.16

Gene sequence:

>1356_bases
ATGGCGCTTTCCCGGGCGCAAGGGGTTTTGGACGAGCTCAAGGCGCTTTTCGGCCCCCGGGCCCTCCTTTCCCGGGCGGC
GAAGGAGGTCTACCGCTACGACGCCATCCTGGTGGGGCCCGAGCCCTTGGCCGTGGTCCTGCCCGAAAGCCGGGAGGAGG
TGGCCGCTTTGGTCCGCCTGGCCCGGCGGCACGGGGTGGTGCTGGTGCCCCGGGGGGCGGGAAGCGGCCTCTCCGGCGGG
GCGGTCCCGGAGGAGGGGTCCATCGTGGTGGCCTTCACCCGGATGACCCGCCTCGAGGTGGACCCCCACACCCAGACGGC
CTGGGCCGAGCCCGGGGTGACCACGGCCCGGGTCTCCGAGGCGGCGAGGCCCTACGGCCTCTTCTACCCCCCGGACCCCG
CCTCCTACCGCACCAGCACCCTGGGGGGGAACCTGGCGGAGAACGCCGGGGGGCCCCTCTGCTTCAAGTACGGGGTCACC
GGGGACTACGTTTTGGAGCTGGAGTGGGTGGACGACGAGGGCGGGATCCAGCGCCAGGGGCGCGCCGCCTACGACCTCCC
GGGCCTCCTCATCGGCTCGGAGGGGACCTTGGGCCTGGTGACGGGGGCGAGGCTCCGCCTTCTTCCCTTGCCCCGGCACC
GGGCCGCCCTCCTGGCCCACTTTCCCGGGGTGGAGCCCCTGGCCGAGGCGGTCTCCGAGGCGGTGGCCTCGGGGGCCGTG
CCCGCCCGCATGGAGTTCATGGACCCGGCCTGCGCGGGCGCCGTGGAGGACTACCTGAGGATGGGCCTGCCCCGGGGCCG
GGCCCTCCTCCTGGTGGAGACGGACGGGGAGGAGGCGGACCTCGTGGAGGAGGAGCTTTCCCTGGTGGAGGCGAGCGCCC
GCCGTCACGGGGCCGAGGTGGTCCGCGCGGCGGGCGAGGCGGAGGCCGAGGCCCTCTGGCGGGCCAGGCGGGCGGTGAGC
CCCGCCCTGGGCCGCATCCGTCCCAAGCGGGTGAACGAGGACATCGCCGTGCCCCGCTCGGCCCTGCCCCGGGTGGTGCG
GGAGATTGAGGCTTTGGGGAAGGCCTTCGGCCTCGTGGTGGTGCAGTTCGGCCACATTGGGGACGGGAACCTCCATCCCA
ACATCCTCTTTGATCCCAGGAGGGAGAGCGAGGAGAAGGTCTGGGAGCTCGCCCACGAGATCGCCCGGGTGGCCTTGAGG
CACGGGGGGGTGCTCTCCGGGGAGCACGGCATCGGCCTCATGAAGCGGGACTTCATGCTGGAGGCGGTGGACCCCGAGAC
CCTGGGGGCGCTCCACCGGGTCAAGGAGGCGCTGGACCCCCTGGGCCTCTTCAACCCAGGGAAGGTCCTTCCCTAA

Upstream 100 bases:

>100_bases
GCGCCGCCTCGGCGTACGTGGAAAGCTCCGTGGTCATGTTCCCGGACAACACAAACGTCTGCGACCCGGGGGAGACCGCG
CCCTAGGCTAGGCTAAGGGT

Downstream 100 bases:

>100_bases
GCCCTGTTCGTTTTTCACGGCGTTTTGACGGCGGGGAGGCCATAATGGGGCCATGGAAGGCCTCTACCGCCTCTTTTATG
TCCTCGCCTGGATGGGCCTT

Product: (s)-2-hydroxy-acid oxidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MALSRAQGVLDELKALFGPRALLSRAAKEVYRYDAILVGPEPLAVVLPESREEVAALVRLARRHGVVLVPRGAGSGLSGG
AVPEEGSIVVAFTRMTRLEVDPHTQTAWAEPGVTTARVSEAARPYGLFYPPDPASYRTSTLGGNLAENAGGPLCFKYGVT
GDYVLELEWVDDEGGIQRQGRAAYDLPGLLIGSEGTLGLVTGARLRLLPLPRHRAALLAHFPGVEPLAEAVSEAVASGAV
PARMEFMDPACAGAVEDYLRMGLPRGRALLLVETDGEEADLVEEELSLVEASARRHGAEVVRAAGEAEAEALWRARRAVS
PALGRIRPKRVNEDIAVPRSALPRVVREIEALGKAFGLVVVQFGHIGDGNLHPNILFDPRRESEEKVWELAHEIARVALR
HGGVLSGEHGIGLMKRDFMLEAVDPETLGALHRVKEALDPLGLFNPGKVLP

Sequences:

>Translated_451_residues
MALSRAQGVLDELKALFGPRALLSRAAKEVYRYDAILVGPEPLAVVLPESREEVAALVRLARRHGVVLVPRGAGSGLSGG
AVPEEGSIVVAFTRMTRLEVDPHTQTAWAEPGVTTARVSEAARPYGLFYPPDPASYRTSTLGGNLAENAGGPLCFKYGVT
GDYVLELEWVDDEGGIQRQGRAAYDLPGLLIGSEGTLGLVTGARLRLLPLPRHRAALLAHFPGVEPLAEAVSEAVASGAV
PARMEFMDPACAGAVEDYLRMGLPRGRALLLVETDGEEADLVEEELSLVEASARRHGAEVVRAAGEAEAEALWRARRAVS
PALGRIRPKRVNEDIAVPRSALPRVVREIEALGKAFGLVVVQFGHIGDGNLHPNILFDPRRESEEKVWELAHEIARVALR
HGGVLSGEHGIGLMKRDFMLEAVDPETLGALHRVKEALDPLGLFNPGKVLP
>Mature_450_residues
ALSRAQGVLDELKALFGPRALLSRAAKEVYRYDAILVGPEPLAVVLPESREEVAALVRLARRHGVVLVPRGAGSGLSGGA
VPEEGSIVVAFTRMTRLEVDPHTQTAWAEPGVTTARVSEAARPYGLFYPPDPASYRTSTLGGNLAENAGGPLCFKYGVTG
DYVLELEWVDDEGGIQRQGRAAYDLPGLLIGSEGTLGLVTGARLRLLPLPRHRAALLAHFPGVEPLAEAVSEAVASGAVP
ARMEFMDPACAGAVEDYLRMGLPRGRALLLVETDGEEADLVEEELSLVEASARRHGAEVVRAAGEAEAEALWRARRAVSP
ALGRIRPKRVNEDIAVPRSALPRVVREIEALGKAFGLVVVQFGHIGDGNLHPNILFDPRRESEEKVWELAHEIARVALRH
GGVLSGEHGIGLMKRDFMLEAVDPETLGALHRVKEALDPLGLFNPGKVLP

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=424, Percent_Identity=36.3207547169811, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI37595754, Length=447, Percent_Identity=34.4519015659955, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI119964728, Length=416, Percent_Identity=29.8076923076923, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4501993, Length=460, Percent_Identity=24.5652173913043, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1789351, Length=419, Percent_Identity=40.5727923627685, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1787977, Length=295, Percent_Identity=28.4745762711864, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI48994907, Length=227, Percent_Identity=27.3127753303965, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992373, Length=463, Percent_Identity=29.5896328293737, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71992381, Length=463, Percent_Identity=28.5097192224622, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71992392, Length=357, Percent_Identity=31.9327731092437, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17534361, Length=422, Percent_Identity=26.0663507109005, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17556096, Length=250, Percent_Identity=27.6, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320023, Length=433, Percent_Identity=27.2517321016166, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6320027, Length=429, Percent_Identity=25.6410256410256, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6320764, Length=435, Percent_Identity=27.1264367816092, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI18921117, Length=424, Percent_Identity=29.2452830188679, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24639277, Length=424, Percent_Identity=29.2452830188679, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24639275, Length=424, Percent_Identity=29.2452830188679, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24653753, Length=463, Percent_Identity=27.2138228941685, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48341; Mature: 48210

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSRAQGVLDELKALFGPRALLSRAAKEVYRYDAILVGPEPLAVVLPESREEVAALVRL
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCEEEECCCCEEEECCCCHHHHHHHHHH
ARRHGVVLVPRGAGSGLSGGAVPEEGSIVVAFTRMTRLEVDPHTQTAWAEPGVTTARVSE
HHHCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHH
AARPYGLFYPPDPASYRTSTLGGNLAENAGGPLCFKYGVTGDYVLELEWVDDEGGIQRQG
CCCCCCCCCCCCCCCCCHHHCCCCCHHCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCC
RAAYDLPGLLIGSEGTLGLVTGARLRLLPLPRHRAALLAHFPGVEPLAEAVSEAVASGAV
CCCCCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PARMEFMDPACAGAVEDYLRMGLPRGRALLLVETDGEEADLVEEELSLVEASARRHGAEV
CHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
VRAAGEAEAEALWRARRAVSPALGRIRPKRVNEDIAVPRSALPRVVREIEALGKAFGLVV
HHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCEEE
VQFGHIGDGNLHPNILFDPRRESEEKVWELAHEIARVALRHGGVLSGEHGIGLMKRDFML
EEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHEE
EAVDPETLGALHRVKEALDPLGLFNPGKVLP
EECCHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ALSRAQGVLDELKALFGPRALLSRAAKEVYRYDAILVGPEPLAVVLPESREEVAALVRL
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCEEEECCCCEEEECCCCHHHHHHHHHH
ARRHGVVLVPRGAGSGLSGGAVPEEGSIVVAFTRMTRLEVDPHTQTAWAEPGVTTARVSE
HHHCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHH
AARPYGLFYPPDPASYRTSTLGGNLAENAGGPLCFKYGVTGDYVLELEWVDDEGGIQRQG
CCCCCCCCCCCCCCCCCHHHCCCCCHHCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCC
RAAYDLPGLLIGSEGTLGLVTGARLRLLPLPRHRAALLAHFPGVEPLAEAVSEAVASGAV
CCCCCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PARMEFMDPACAGAVEDYLRMGLPRGRALLLVETDGEEADLVEEELSLVEASARRHGAEV
CHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
VRAAGEAEAEALWRARRAVSPALGRIRPKRVNEDIAVPRSALPRVVREIEALGKAFGLVV
HHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCEEE
VQFGHIGDGNLHPNILFDPRRESEEKVWELAHEIARVALRHGGVLSGEHGIGLMKRDFML
EEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHEE
EAVDPETLGALHRVKEALDPLGLFNPGKVLP
EECCHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]