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The map label for this gene is miaA [H]

Identifier: 55980541

GI number: 55980541

Start: 539567

End: 540475

Strand: Direct

Name: miaA [H]

Synonym: TTHA0572

Alternate gene names: 55980541

Gene position: 539567-540475 (Clockwise)

Preceding gene: 55980539

Following gene: 55980542

Centisome position: 29.17

GC content: 71.73

Gene sequence:

>909_bases
GTGGAGGCGATCCCCGTCCTCGCGGGCCCCACGGGAAGCGGCAAGACCTTTTTGGCCCTCCGCCTGGGGGAGGAGGTCCC
CGTGGAGGTGGTCTCCGCCGACGCCACCATGGTCTACCGGGGCCTGGACATCGGGACGGACAAGCCCACGCCCGAGGAGC
GGGCGCGGGTGCCCCACCACCTGGTGGACGTCCTCGAGCCCCACGAGGCCATGAGCGTGGCCCGCTTCCTCGCCCTGGCC
GAGGAGGCCATCGCCCATGTCCTTTCCCGGGGAAAGCTCCCCTTGGTGGTGGGGGGGACGGGCTACTACATCCGCGCCCT
CTCCGAGGGGCTTCACGACCTTCCCCCGCCGGACCCCGGGGTCCAGGAGGCCCTATGGGCGGAGCTTGAGGCGCGGGGCC
TTGAGGCCCTCCTCGCTGAGCTCGCCCGGGCGAGCCCCGAGGACGCCCGCCGCGTGGGAAAAAACCCGAGGAGGCTCGTC
CGGGCCCTGGAGGTCCTGAGGCGCACGGGCACTCCCCCGGCCCGGTTTCCCAAGAGGCCCCCCCGCTTCCGCTACAAGAA
GCTCGTCCTCTGGCCCGACCGGGCCTGGCTTTTCCCGAGGCTGGAGGAAAGGGCCAAGGCCCAGTTCGCCCGGGGGCTCG
TGGAGGAGGTGCGGGGGCTCCTTGAGCGCTACCCCAGGATGCCCACCGCCCTCCAGGCCATCGGCTACAAGGAGGTGGCG
GGCCACCTCCTGGGGGCCTACGGCCTGGAGGAGGCGCTAGAGCGGGACATCCGGGCGGTGAAGGCCTACGCCAAAAGGCA
GTACACCTGGTTCCGCCACGAGCCCGGGGACGTGGTCTACCTGCCCCGGGGGGGCGAGGAGGCCTACGTGGGCTTCCGGG
ACTGGCTTTGCCTCCACTTCGGGCTATAG

Upstream 100 bases:

>100_bases
GGAGGTAGGCGAGCTCGGCGATGCGCTCCTGCAGTTCCTTCAGCTTTCTCAGGGTTTCCAGGCGGTCGTGGCGCTCCAGC
ATGCCCTTAGCATAAGGGAC

Downstream 100 bases:

>100_bases
TGGGGGCATGTTGGCCCACGAGATCCGCGCCCGCGTGGCCCGGGGGGAGGTTTCCCCCCTGGAGGTGGCCCAGGCCTACC
TGAAACGGGTCCAGGAGCTG

Product: tRNA delta(2)-isopentenylpyrophosphate transferase

Products: NA

Alternate protein names: Dimethylallyl diphosphate:tRNA dimethylallyltransferase; DMAPP:tRNA dimethylallyltransferase; DMATase; Isopentenyl-diphosphate:tRNA isopentenyltransferase; IPP transferase; IPPT; IPTase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHHLVDVLEPHEAMSVARFLALA
EEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPGVQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLV
RALEVLRRTGTPPARFPKRPPRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLERYPRMPTALQAIGYKEVA
GHLLGAYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLCLHFGL

Sequences:

>Translated_302_residues
MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHHLVDVLEPHEAMSVARFLALA
EEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPGVQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLV
RALEVLRRTGTPPARFPKRPPRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLERYPRMPTALQAIGYKEVA
GHLLGAYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLCLHFGL
>Mature_302_residues
MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHHLVDVLEPHEAMSVARFLALA
EEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPGVQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLV
RALEVLRRTGTPPARFPKRPPRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLERYPRMPTALQAIGYKEVA
GHLLGAYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLCLHFGL

Specific function: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) [H]

COG id: COG0324

COG function: function code J; tRNA delta(2)-isopentenylpyrophosphate transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IPP transferase family [H]

Homologues:

Organism=Homo sapiens, GI31581534, Length=316, Percent_Identity=31.9620253164557, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1790613, Length=274, Percent_Identity=36.4963503649635, Blast_Score=161, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI25144712, Length=267, Percent_Identity=28.4644194756554, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324848, Length=290, Percent_Identity=30, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24649830, Length=271, Percent_Identity=33.9483394833948, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002627
- InterPro:   IPR018022 [H]

Pfam domain/function: PF01715 IPPT [H]

EC number: =2.5.1.75 [H]

Molecular weight: Translated: 33812; Mature: 33812

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHH
CCCCCEEECCCCCCCEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHCCHHH
LVDVLEPHEAMSVARFLALAEEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
VQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLVRALEVLRRTGTPPARFPKRP
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLERYPRMPTALQAIGYKEVA
CCCCCEEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHH
GHLLGAYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLCLHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHC
GL
CC
>Mature Secondary Structure
MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHH
CCCCCEEECCCCCCCEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCHHHHCCHHH
LVDVLEPHEAMSVARFLALAEEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
VQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLVRALEVLRRTGTPPARFPKRP
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLERYPRMPTALQAIGYKEVA
CCCCCEEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHH
GHLLGAYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLCLHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHC
GL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA