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The map label for this gene is dppA [C]

Identifier: 55980438

GI number: 55980438

Start: 437374

End: 439119

Strand: Direct

Name: dppA [C]

Synonym: TTHA0469

Alternate gene names: 55980438

Gene position: 437374-439119 (Clockwise)

Preceding gene: 55980432

Following gene: 55980439

Centisome position: 23.65

GC content: 64.03

Gene sequence:

>1746_bases
ATGAGAAAAGCGGTGTTGCTGGTGGGCATCTTGGCTTTGGCGGGCGTCGCCTCGGCCCAGACCTTCGTCTGGCCCCAGAA
GTGGACGGTGGCCAAGCCCTCCGAGGCGAAGCGGGGGGGGACGCTTAGGGGTTACACCATCTCCGACTACCGCACCTTCA
ACCCCTTCCTCACCGCGGAGGCGAACAGCATTCCCGACCTCATCAACCCTTACGGCCTCGTCCGGCGCGACCCCACCACG
GGCGACTGGATCCCCTACATGGCGGAGTCCTGGACCATAAGCCCCAACAAGCTGGAGATCACCTTCAAGATCCGCAAGGG
CATGAAGTGGTCGGACGGCCGGCCCATCACCGCCGACGACTGGATCATGACCTGGCGGATCCACACCGACAAGGCGGTGG
GCTCCAACAGCTACGACTCCTTCTTCATTGACGGCAAGCCCATCGTCCTCAGGAAGCTTGACGACTACACGATCCGCTTC
ATCTACCCCAAGACGGACGCGGAGGCCTTCGCCATCGCCAGCTTCGCCCCCTGGCCCGCCCACGTCTTCGGCCCCGTCTA
CCAGAAGGAGGGGGCGGAGGGCATCAAGAAGATGTGGACCCTGAACGAGGACCCGGCCAAGATCGTCTCCGCCGGGCCTT
GGGTCGTGGAGAGCTACCGCCCCGGGGAACGGGTGGTCCTGAAGCGGAACCCCTCCTTCGGCGAGTGGAACAAGGACGAG
GCCGGCAACCCCCTTCCCTACCTGGACCGGTACGAGATCCGGATCGTCAAGGACGTGAACGCCGCCTTGGCGGAGTTCCT
GGCGGGGAACATTGACATCTTCAACCCCTCCACCGTGGACCAGATTTCCCAGATCCGCCAGGCCGTCCAGCAGGGCCGCC
TGGACGCCACCATCAAGGTCAACGCCTCCCCCGTGGCCAGCAGCCAGTTCATGGTCTTCAACTGGAACAAGGCCTCCGAC
CCCTTCAAGCAAAGCCTCTTCCGCTCCGACAAGTTCCGCCGGGCCATGAGCCACCTGGTGAACCGCCAGGCGGTGATTGA
CATCGTCTACGGCGGCCTGGGCATCCCCATGTACTCCAGCGTCTACCCGGTCCTCACCCAGTGGATTAACCCCAAGGTGC
CCAAGTACGAGTACGACCCCAAGCAGGCGGCCAAACTCCTCGCCGAGCTCGGCTTCACGAAGAAGGACCGGGAGGGGTAC
CTGGTGGACTCCAAGGGGCGGCGGATTGAGTTCAACCTCGCCACCAACGCCGGCAACACCCAGCGGGAGCAGATCGCCAA
GCTCATCGTGGACGAGGCCAAGAAGGTGGGGGTGAAGGTCAACTTCCAGGCCATTGACTTCAACACCCTGGTGGGCCAGC
TCCTCTCCTCGGGCCCTGACCGGCCCTTTGACGCCATCATCATCGGCCTGACGGGCGGCGGCCTGGACTGGCCCTTCGGT
TCCAACGTGGTGCCCTGCAAGGGGAACCTGCACATGTGGAACAAGTCCGGCCAGTGCCTGGACCCCCGGGAGACCCTCAT
GGAGAAGCTCTACTACCAGGGCCGCACGGAGCTGGACTTCAAGAAGCGGGTGGAGATCGGCTACCGCATGCAGGAGGTTG
AGGCGGAGCTCCTCCCCGTCATCTACATCGCCGGGCCCAACTACCACCCCGCCTGGAACAACCGCCTGGGCGGCGAGCAC
CCCGACGCCATCATCTCCAGCATCTGGGGCTCCCGTGAGGTGGAGCTCACCTTCATCAAGAAGTGA

Upstream 100 bases:

>100_bases
ATACACCCGTCCTCCTGACCTTTGCAAGGCAAGCCCACCCTTGACAGGGTCTAACCCCGCCCGGTAGTGTGGGGCCGTAC
GCGACGCAGGGAGGTTTTGT

Downstream 100 bases:

>100_bases
GCTAGCTTGACGCTCATCCCCGGGGCCGGGCCGCCCCGGGGATGTCTTGGAAAGCCATGGCGAGCTACATCCTCAAGCGC
ATTCTCTCCCTGATCCCCAC

Product: peptide ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MRKAVLLVGILALAGVASAQTFVWPQKWTVAKPSEAKRGGTLRGYTISDYRTFNPFLTAEANSIPDLINPYGLVRRDPTT
GDWIPYMAESWTISPNKLEITFKIRKGMKWSDGRPITADDWIMTWRIHTDKAVGSNSYDSFFIDGKPIVLRKLDDYTIRF
IYPKTDAEAFAIASFAPWPAHVFGPVYQKEGAEGIKKMWTLNEDPAKIVSAGPWVVESYRPGERVVLKRNPSFGEWNKDE
AGNPLPYLDRYEIRIVKDVNAALAEFLAGNIDIFNPSTVDQISQIRQAVQQGRLDATIKVNASPVASSQFMVFNWNKASD
PFKQSLFRSDKFRRAMSHLVNRQAVIDIVYGGLGIPMYSSVYPVLTQWINPKVPKYEYDPKQAAKLLAELGFTKKDREGY
LVDSKGRRIEFNLATNAGNTQREQIAKLIVDEAKKVGVKVNFQAIDFNTLVGQLLSSGPDRPFDAIIIGLTGGGLDWPFG
SNVVPCKGNLHMWNKSGQCLDPRETLMEKLYYQGRTELDFKKRVEIGYRMQEVEAELLPVIYIAGPNYHPAWNNRLGGEH
PDAIISSIWGSREVELTFIKK

Sequences:

>Translated_581_residues
MRKAVLLVGILALAGVASAQTFVWPQKWTVAKPSEAKRGGTLRGYTISDYRTFNPFLTAEANSIPDLINPYGLVRRDPTT
GDWIPYMAESWTISPNKLEITFKIRKGMKWSDGRPITADDWIMTWRIHTDKAVGSNSYDSFFIDGKPIVLRKLDDYTIRF
IYPKTDAEAFAIASFAPWPAHVFGPVYQKEGAEGIKKMWTLNEDPAKIVSAGPWVVESYRPGERVVLKRNPSFGEWNKDE
AGNPLPYLDRYEIRIVKDVNAALAEFLAGNIDIFNPSTVDQISQIRQAVQQGRLDATIKVNASPVASSQFMVFNWNKASD
PFKQSLFRSDKFRRAMSHLVNRQAVIDIVYGGLGIPMYSSVYPVLTQWINPKVPKYEYDPKQAAKLLAELGFTKKDREGY
LVDSKGRRIEFNLATNAGNTQREQIAKLIVDEAKKVGVKVNFQAIDFNTLVGQLLSSGPDRPFDAIIIGLTGGGLDWPFG
SNVVPCKGNLHMWNKSGQCLDPRETLMEKLYYQGRTELDFKKRVEIGYRMQEVEAELLPVIYIAGPNYHPAWNNRLGGEH
PDAIISSIWGSREVELTFIKK
>Mature_581_residues
MRKAVLLVGILALAGVASAQTFVWPQKWTVAKPSEAKRGGTLRGYTISDYRTFNPFLTAEANSIPDLINPYGLVRRDPTT
GDWIPYMAESWTISPNKLEITFKIRKGMKWSDGRPITADDWIMTWRIHTDKAVGSNSYDSFFIDGKPIVLRKLDDYTIRF
IYPKTDAEAFAIASFAPWPAHVFGPVYQKEGAEGIKKMWTLNEDPAKIVSAGPWVVESYRPGERVVLKRNPSFGEWNKDE
AGNPLPYLDRYEIRIVKDVNAALAEFLAGNIDIFNPSTVDQISQIRQAVQQGRLDATIKVNASPVASSQFMVFNWNKASD
PFKQSLFRSDKFRRAMSHLVNRQAVIDIVYGGLGIPMYSSVYPVLTQWINPKVPKYEYDPKQAAKLLAELGFTKKDREGY
LVDSKGRRIEFNLATNAGNTQREQIAKLIVDEAKKVGVKVNFQAIDFNTLVGQLLSSGPDRPFDAIIIGLTGGGLDWPFG
SNVVPCKGNLHMWNKSGQCLDPRETLMEKLYYQGRTELDFKKRVEIGYRMQEVEAELLPVIYIAGPNYHPAWNNRLGGEH
PDAIISSIWGSREVELTFIKK

Specific function: Probably part of a binding-protein-dependent transport system [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=541, Percent_Identity=26.0628465804067, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787551, Length=404, Percent_Identity=23.019801980198, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787762, Length=273, Percent_Identity=24.1758241758242, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 65530; Mature: 65530

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAVLLVGILALAGVASAQTFVWPQKWTVAKPSEAKRGGTLRGYTISDYRTFNPFLTAE
CCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEECEEECCCEECCCEEEEC
ANSIPDLINPYGLVRRDPTTGDWIPYMAESWTISPNKLEITFKIRKGMKWSDGRPITADD
CCCCCHHCCCCCCEECCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCCCCCCCCCCCCC
WIMTWRIHTDKAVGSNSYDSFFIDGKPIVLRKLDDYTIRFIYPKTDAEAFAIASFAPWPA
EEEEEEEECCCCCCCCCCCEEEECCCEEEEEECCCEEEEEEEECCCCCEEEEEECCCCCH
HVFGPVYQKEGAEGIKKMWTLNEDPAKIVSAGPWVVESYRPGERVVLKRNPSFGEWNKDE
HHHCCHHHHCCHHHHHHHHCCCCCHHHHEECCCEEEECCCCCCEEEEEECCCCCCCCCCC
AGNPLPYLDRYEIRIVKDVNAALAEFLAGNIDIFNPSTVDQISQIRQAVQQGRLDATIKV
CCCCCCCCCCEEEEEEEHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEE
NASPVASSQFMVFNWNKASDPFKQSLFRSDKFRRAMSHLVNRQAVIDIVYGGLGIPMYSS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHH
VYPVLTQWINPKVPKYEYDPKQAAKLLAELGFTKKDREGYLVDSKGRRIEFNLATNAGNT
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEEECCCCCH
QREQIAKLIVDEAKKVGVKVNFQAIDFNTLVGQLLSSGPDRPFDAIIIGLTGGGLDWPFG
HHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCC
SNVVPCKGNLHMWNKSGQCLDPRETLMEKLYYQGRTELDFKKRVEIGYRMQEVEAELLPV
CCEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHCEEEE
IYIAGPNYHPAWNNRLGGEHPDAIISSIWGSREVELTFIKK
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MRKAVLLVGILALAGVASAQTFVWPQKWTVAKPSEAKRGGTLRGYTISDYRTFNPFLTAE
CCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEECEEECCCEECCCEEEEC
ANSIPDLINPYGLVRRDPTTGDWIPYMAESWTISPNKLEITFKIRKGMKWSDGRPITADD
CCCCCHHCCCCCCEECCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCCCCCCCCCCCCC
WIMTWRIHTDKAVGSNSYDSFFIDGKPIVLRKLDDYTIRFIYPKTDAEAFAIASFAPWPA
EEEEEEEECCCCCCCCCCCEEEECCCEEEEEECCCEEEEEEEECCCCCEEEEEECCCCCH
HVFGPVYQKEGAEGIKKMWTLNEDPAKIVSAGPWVVESYRPGERVVLKRNPSFGEWNKDE
HHHCCHHHHCCHHHHHHHHCCCCCHHHHEECCCEEEECCCCCCEEEEEECCCCCCCCCCC
AGNPLPYLDRYEIRIVKDVNAALAEFLAGNIDIFNPSTVDQISQIRQAVQQGRLDATIKV
CCCCCCCCCCEEEEEEEHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEE
NASPVASSQFMVFNWNKASDPFKQSLFRSDKFRRAMSHLVNRQAVIDIVYGGLGIPMYSS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHH
VYPVLTQWINPKVPKYEYDPKQAAKLLAELGFTKKDREGYLVDSKGRRIEFNLATNAGNT
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEEECCCCCH
QREQIAKLIVDEAKKVGVKVNFQAIDFNTLVGQLLSSGPDRPFDAIIIGLTGGGLDWPFG
HHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCC
SNVVPCKGNLHMWNKSGQCLDPRETLMEKLYYQGRTELDFKKRVEIGYRMQEVEAELLPV
CCEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHCEEEE
IYIAGPNYHPAWNNRLGGEHPDAIISSIWGSREVELTFIKK
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]