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The map label for this gene is bdbC [H]

Identifier: 55980404

GI number: 55980404

Start: 409381

End: 409806

Strand: Reverse

Name: bdbC [H]

Synonym: TTHA0435

Alternate gene names: 55980404

Gene position: 409806-409381 (Counterclockwise)

Preceding gene: 55980405

Following gene: 55980402

Centisome position: 22.15

GC content: 67.37

Gene sequence:

>426_bases
ATGCTGGAGGCCGTGGAGCGAAAGACCCTCTACCTGGCCTTCGCCTGGGTGGTGGCCCTGGTGGCCACCCTGGGCAGCCT
CTACTACTCCGAGGTGCGCCTCTTCCTGCCCTGCGAGCTCTGCTGGTACCAGCGGATCTTCATGTACCCCCAGGCGGTGA
TCCTGGGCCTTGCCCTCTGGCGGCAGGACTTTGGCGTCTGGCCCTACAGCCTCGCCCTCTCCCTCCTTGGGGGAAGCGTG
AGCGTCCTCCACCTCACCCAGCAGTGGTTCCCGGGACTCTTCCCTCTGGCCTGCAAACCCCCCGTGCCCTGCAGCGCGGA
GTACATCCCCGAGTTCCCCATCCCCCTCCAGGCCCTCATCGCCTTCACCCTCATCGCCCTCGCCATGGGCCTTCTCGCCC
GCCAGGCCCGAGGTGGAAGGCGTTGA

Upstream 100 bases:

>100_bases
CCGAACCAGGCTTTGGGGCATTAGCCCACGAGCAGCCGCCCAAGGAGCCAGAGGTTGAGCCCGGTCACGAAGAGCGCGGC
CCCCCAGGCCAAGGCCCGGT

Downstream 100 bases:

>100_bases
GGAAGAGGGGAAGCGCCCGCCCCTTCTCCTCCTGGGCCCGCAAGGCCTCCTCAAAGGCCCAGGGCTCCATGAGGAGGGGA
GGGAGGCGGAGCCAGCCCAG

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase C; Thiol-disulfide oxidoreductase C [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MLEAVERKTLYLAFAWVVALVATLGSLYYSEVRLFLPCELCWYQRIFMYPQAVILGLALWRQDFGVWPYSLALSLLGGSV
SVLHLTQQWFPGLFPLACKPPVPCSAEYIPEFPIPLQALIAFTLIALAMGLLARQARGGRR

Sequences:

>Translated_141_residues
MLEAVERKTLYLAFAWVVALVATLGSLYYSEVRLFLPCELCWYQRIFMYPQAVILGLALWRQDFGVWPYSLALSLLGGSV
SVLHLTQQWFPGLFPLACKPPVPCSAEYIPEFPIPLQALIAFTLIALAMGLLARQARGGRR
>Mature_141_residues
MLEAVERKTLYLAFAWVVALVATLGSLYYSEVRLFLPCELCWYQRIFMYPQAVILGLALWRQDFGVWPYSLALSLLGGSV
SVLHLTQQWFPGLFPLACKPPVPCSAEYIPEFPIPLQALIAFTLIALAMGLLARQARGGRR

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168, although it can partially substitute for BdbB when the

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family. BdbC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR012187 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 15850; Mature: 15850

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEAVERKTLYLAFAWVVALVATLGSLYYSEVRLFLPCELCWYQRIFMYPQAVILGLALW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RQDFGVWPYSLALSLLGGSVSVLHLTQQWFPGLFPLACKPPVPCSAEYIPEFPIPLQALI
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
AFTLIALAMGLLARQARGGRR
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLEAVERKTLYLAFAWVVALVATLGSLYYSEVRLFLPCELCWYQRIFMYPQAVILGLALW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RQDFGVWPYSLALSLLGGSVSVLHLTQQWFPGLFPLACKPPVPCSAEYIPEFPIPLQALI
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
AFTLIALAMGLLARQARGGRR
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 10455116; 11844773; 11744713; 11872755 [H]