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The map label for this gene is yciL [C]

Identifier: 55980188

GI number: 55980188

Start: 214538

End: 215245

Strand: Direct

Name: yciL [C]

Synonym: TTHA0219

Alternate gene names: 55980188

Gene position: 214538-215245 (Clockwise)

Preceding gene: 55980187

Following gene: 55980189

Centisome position: 11.6

GC content: 73.16

Gene sequence:

>708_bases
ATGAAGGCGCTCCGCCTCCAGGCCTTCCTCGCCCGGGCCGGGGTGGCGAGCCGCCGCAAGGCGGAGGACCTCATCCGCGA
GGGGCGGGTGCGGGTGAACGGGAAGGTGGCGGTCCTCGGCCAGAAGGTGGGGCCTGAGGACCTCGTGGAGGTGGACGGGA
AGCGGGTGGAGTTGCCCCAAAAGCGGCTGGTCCTCGCCCTCCACAAGCCCAAGGGGTACACCACCACCCGCCACGACCCC
CACGCCCGGCGCACCGTCTTTGACCTCCTCCCGAAGATCCCCGGCCTCCACCCCGTGGGCCGCCTGGACCGGGACTCCGA
GGGCCTTCTCCTCCTCACCAACGACGGCGACCTCACCCACCGCCTCACCCACCCCCGCTTCGGGGTGCGGAAGGTCTACC
GGGTGTGGACGGAGGGGGGGACGCTGCCCAAGGAGGTGTGCAGAAGGCTCCTCTTGGGCGTGGACCTCGAGGACGGCCCC
GCCCGGGCCCTCGCCTGCCGCCCGGCCCCCGGGGGGGCGGTCCTCGTCCTCGCGGAAGGGCGCAAGCGGGAGGTGCGGCG
GATGCTCCAGAGGGTGGGCTACCCGGTGCGGCGCCTCCTGAGGCTCCAGGTGGGGCCCATCCGCCTCGGGGACCTCCCCC
CCGGGAAGTGGCGGAGGCTTTCCGAGAGGGAGGTCAAGGCCCTCCTCCGGCTCGTGGGGCTAGAATGA

Upstream 100 bases:

>100_bases
ACTTTGAGCTCTCCTTGGCCTTGGAGTTTTTGGGGTTTTCCGGGAAGGAGCTGGAGGAGGGCCTCAAGGCCCTCAAGGAG
AAGCGCCCCCCCGAGTTCCC

Downstream 100 bases:

>100_bases
AGGGCATGTTCACGCCGGGCAACGGACCCGTGCAGATCAGCGCCGAGGCCATAAAGAAGCGGGTGGAGGAGCTGGGGGGG
GAGATCGCCCGGGACTACCA

Product: ribosomal large subunit pseudouridine synthase B

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKALRLQAFLARAGVASRRKAEDLIREGRVRVNGKVAVLGQKVGPEDLVEVDGKRVELPQKRLVLALHKPKGYTTTRHDP
HARRTVFDLLPKIPGLHPVGRLDRDSEGLLLLTNDGDLTHRLTHPRFGVRKVYRVWTEGGTLPKEVCRRLLLGVDLEDGP
ARALACRPAPGGAVLVLAEGRKREVRRMLQRVGYPVRRLLRLQVGPIRLGDLPPGKWRRLSEREVKALLRLVGLE

Sequences:

>Translated_235_residues
MKALRLQAFLARAGVASRRKAEDLIREGRVRVNGKVAVLGQKVGPEDLVEVDGKRVELPQKRLVLALHKPKGYTTTRHDP
HARRTVFDLLPKIPGLHPVGRLDRDSEGLLLLTNDGDLTHRLTHPRFGVRKVYRVWTEGGTLPKEVCRRLLLGVDLEDGP
ARALACRPAPGGAVLVLAEGRKREVRRMLQRVGYPVRRLLRLQVGPIRLGDLPPGKWRRLSEREVKALLRLVGLE
>Mature_235_residues
MKALRLQAFLARAGVASRRKAEDLIREGRVRVNGKVAVLGQKVGPEDLVEVDGKRVELPQKRLVLALHKPKGYTTTRHDP
HARRTVFDLLPKIPGLHPVGRLDRDSEGLLLLTNDGDLTHRLTHPRFGVRKVYRVWTEGGTLPKEVCRRLLLGVDLEDGP
ARALACRPAPGGAVLVLAEGRKREVRRMLQRVGYPVRRLLRLQVGPIRLGDLPPGKWRRLSEREVKALLRLVGLE

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=244, Percent_Identity=43.0327868852459, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1790453, Length=234, Percent_Identity=32.9059829059829, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788510, Length=232, Percent_Identity=34.4827586206897, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87081838, Length=180, Percent_Identity=36.6666666666667, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 26395; Mature: 26395

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALRLQAFLARAGVASRRKAEDLIREGRVRVNGKVAVLGQKVGPEDLVEVDGKRVELPQ
CCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCEEEEEECCCCHHHHHHCCCCEECCCH
KRLVLALHKPKGYTTTRHDPHARRTVFDLLPKIPGLHPVGRLDRDSEGLLLLTNDGDLTH
HHEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEE
RLTHPRFGVRKVYRVWTEGGTLPKEVCRRLLLGVDLEDGPARALACRPAPGGAVLVLAEG
ECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEECC
RKREVRRMLQRVGYPVRRLLRLQVGPIRLGDLPPGKWRRLSEREVKALLRLVGLE
CHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKALRLQAFLARAGVASRRKAEDLIREGRVRVNGKVAVLGQKVGPEDLVEVDGKRVELPQ
CCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCEEEEEECCCCHHHHHHCCCCEECCCH
KRLVLALHKPKGYTTTRHDPHARRTVFDLLPKIPGLHPVGRLDRDSEGLLLLTNDGDLTH
HHEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEE
RLTHPRFGVRKVYRVWTEGGTLPKEVCRRLLLGVDLEDGPARALACRPAPGGAVLVLAEG
ECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEECC
RKREVRRMLQRVGYPVRRLLRLQVGPIRLGDLPPGKWRRLSEREVKALLRLVGLE
CHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]