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The map label for this gene is folB [H]

Identifier: 55980159

GI number: 55980159

Start: 186188

End: 186544

Strand: Reverse

Name: folB [H]

Synonym: TTHA0190

Alternate gene names: 55980159

Gene position: 186544-186188 (Counterclockwise)

Preceding gene: 55980160

Following gene: 55980158

Centisome position: 10.08

GC content: 66.39

Gene sequence:

>357_bases
ATGGGGGAGATCGCCCTTCTCGGGCTTGAGTTCTACGGGCGCCACGGGGTCATGCCCGAGGAGGGGCGGCTTGGGGCCCG
GTTCGTGGTGGACCTCTGGCTTTCCGTGCCCTTTGAGGGCAAGGGGGACAGGCTGGAGGAGACCGTGGACTACGCCGCCG
TCTACGCCCTGGTGGAGGAGGCGGTGCGCCACCGCCGCTTCTACCTCATTGAGGCCCTGGCGGACCATTTGGCGGAGGAG
CTCCTAAAGGCCTTTCCCCGCCTCCAGGCGGTTCGGGTCCGGGTCCACAAGCCCCACGCCCCCATCCCCGGGGTTTTTCG
GGACGTCTACGCCGAAACGCAAAAATCCCGTATTTGA

Upstream 100 bases:

>100_bases
GTGGCCGCCCACCTCTTCGCCGTGATGAAGGGGGTGAGGTTGCTTCGGGTCCACGACGTGCGGGCCCACCGGGAGGCCCT
TGGGGTTTGGGAGGCGCTGT

Downstream 100 bases:

>100_bases
GGGCGTTTCTTCCCCTCATCTTGCGCTCATGGGCAGGCTGTGGTAGGATGCCCCCGCCCTTAAGGGCTAAGCCAACGTTT
ATCCCGCCCCCGCCGCTCAA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MGEIALLGLEFYGRHGVMPEEGRLGARFVVDLWLSVPFEGKGDRLEETVDYAAVYALVEEAVRHRRFYLIEALADHLAEE
LLKAFPRLQAVRVRVHKPHAPIPGVFRDVYAETQKSRI

Sequences:

>Translated_118_residues
MGEIALLGLEFYGRHGVMPEEGRLGARFVVDLWLSVPFEGKGDRLEETVDYAAVYALVEEAVRHRRFYLIEALADHLAEE
LLKAFPRLQAVRVRVHKPHAPIPGVFRDVYAETQKSRI
>Mature_117_residues
GEIALLGLEFYGRHGVMPEEGRLGARFVVDLWLSVPFEGKGDRLEETVDYAAVYALVEEAVRHRRFYLIEALADHLAEEL
LKAFPRLQAVRVRVHKPHAPIPGVFRDVYAETQKSRI

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13471; Mature: 13340

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIALLGLEFYGRHGVMPEEGRLGARFVVDLWLSVPFEGKGDRLEETVDYAAVYALVEE
CCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AVRHRRFYLIEALADHLAEELLKAFPRLQAVRVRVHKPHAPIPGVFRDVYAETQKSRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEIALLGLEFYGRHGVMPEEGRLGARFVVDLWLSVPFEGKGDRLEETVDYAAVYALVEE
CCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AVRHRRFYLIEALADHLAEELLKAFPRLQAVRVRVHKPHAPIPGVFRDVYAETQKSRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]