Click here to switch to the map view.

The map label for this gene is fadR [H]

Identifier: 55980136

GI number: 55980136

Start: 162660

End: 163229

Strand: Direct

Name: fadR [H]

Synonym: TTHA0167

Alternate gene names: 55980136

Gene position: 162660-163229 (Clockwise)

Preceding gene: 55980132

Following gene: 55980137

Centisome position: 8.79

GC content: 69.47

Gene sequence:

>570_bases
GTGGCCGCGATGATAACCCCTCCGGGGGCCGGCGTCAAGGACAAGAAGCGGGCCATCCTTGAGGCCACCCTGGCCGTGCT
CCGGGAGCGGGGCCTCTCCGGGCTCAAGATGGAGGAGGTGGCCCGGAGGGCGGAGGTGGGCAAGGGCACCATCTACCTCT
ACTTCCGCGACAAGAGGGACCTGCTCAAGGCCCTGGTGGAGGAGCGCACCTGGGCCTTCTACCGCGAGGTGGAGGAGGTG
GTGCGCCGCAAGGCGCCTTTTTTCGTGCGCCTCGAGGAGGTGCTGAGGCGCCGCCTGGCCTGGGTGCAGGAGTGGCGGGG
CCTCTGGGCCGCCGTGGCCCGGGAGGCCATGGACGACCCCACCCCCTGGCTCAAGGGCCTCCACGAGCACTACCTCCGCC
TCCTGGAGGAGCTTTTGCGGTCGGGCCAGTCGGAGGGGGCCGTGCGCACGGGCCTCTCCCCCAGGGCCACGGCCGCGGTC
ATCGCGGCGATGGGGTGCACCCCTTCCTTGGAGGTGGAAGCCTATTTGGAGCATCTTATGGAGGTGCTCCGGAAAGGAGT
AGAGCCGTGA

Upstream 100 bases:

>100_bases
AAGGCGAAGTAGCCCTGACGCACGCTTTCACCTCCCCTGTACCTCCTAGGGTAGCGCACCCCTCATGAAAGGGGAAGGAC
GGTGTGGTAGACTGGGGGTC

Downstream 100 bases:

>100_bases
AAGAGTTCAGGCCTGGGGACAAGGTGGTCTTGCCCCCCTACGGGGTCGGCGTGGTGGCGGGCATCGCCCAGCGGAGCGTA
AGCGGGGTGAGCCGGGCCTA

Product: TetR/AcrR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAAMITPPGAGVKDKKRAILEATLAVLRERGLSGLKMEEVARRAEVGKGTIYLYFRDKRDLLKALVEERTWAFYREVEEV
VRRKAPFFVRLEEVLRRRLAWVQEWRGLWAAVAREAMDDPTPWLKGLHEHYLRLLEELLRSGQSEGAVRTGLSPRATAAV
IAAMGCTPSLEVEAYLEHLMEVLRKGVEP

Sequences:

>Translated_189_residues
MAAMITPPGAGVKDKKRAILEATLAVLRERGLSGLKMEEVARRAEVGKGTIYLYFRDKRDLLKALVEERTWAFYREVEEV
VRRKAPFFVRLEEVLRRRLAWVQEWRGLWAAVAREAMDDPTPWLKGLHEHYLRLLEELLRSGQSEGAVRTGLSPRATAAV
IAAMGCTPSLEVEAYLEHLMEVLRKGVEP
>Mature_188_residues
AAMITPPGAGVKDKKRAILEATLAVLRERGLSGLKMEEVARRAEVGKGTIYLYFRDKRDLLKALVEERTWAFYREVEEVV
RRKAPFFVRLEEVLRRRLAWVQEWRGLWAAVAREAMDDPTPWLKGLHEHYLRLLEELLRSGQSEGAVRTGLSPRATAAVI
AAMGCTPSLEVEAYLEHLMEVLRKGVEP

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21539; Mature: 21408

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAMITPPGAGVKDKKRAILEATLAVLRERGLSGLKMEEVARRAEVGKGTIYLYFRDKRD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCHHH
LLKALVEERTWAFYREVEEVVRRKAPFFVRLEEVLRRRLAWVQEWRGLWAAVAREAMDDP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TPWLKGLHEHYLRLLEELLRSGQSEGAVRTGLSPRATAAVIAAMGCTPSLEVEAYLEHLM
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
EVLRKGVEP
HHHHHCCCC
>Mature Secondary Structure 
AAMITPPGAGVKDKKRAILEATLAVLRERGLSGLKMEEVARRAEVGKGTIYLYFRDKRD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCHHH
LLKALVEERTWAFYREVEEVVRRKAPFFVRLEEVLRRRLAWVQEWRGLWAAVAREAMDDP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TPWLKGLHEHYLRLLEELLRSGQSEGAVRTGLSPRATAAVIAAMGCTPSLEVEAYLEHLM
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
EVLRKGVEP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]