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The map label for this gene is namA [H]

Identifier: 55980126

GI number: 55980126

Start: 150186

End: 151235

Strand: Reverse

Name: namA [H]

Synonym: TTHA0157

Alternate gene names: 55980126

Gene position: 151235-150186 (Counterclockwise)

Preceding gene: 55980130

Following gene: 55980122

Centisome position: 8.18

GC content: 72.67

Gene sequence:

>1050_bases
ATGGGACTCCTCTTTACCCCTCTGGAGCTTCGCGGCCTCCGGCTCAAGAATCGCCTGGCCATGTCCCCCATGTGCCAGTA
CTCGGCCACGGAAGGGGGAGAGGTCACGGACTGGCACCTCCTCCACTACCCCACCCGGGCCCTGGGCGGGGTGGGGCTCG
TGATCGTGGAGGCCACGGCGGTCCTCCCCGAAGGGAGGATCAGCCCCTTTGACCTCGGGATCTGGTCCGAGGACCACCTC
CCGGGCCTTAGGGAGCTCGCCCGGCGCATCCGGGAGGCGGGGGCGGTGCCGGGGATCCAGCTCGCCCACGCCGGGCGCAA
GGCGGGGACGGCGAGGCCCTGGGAAGGGGGAAGGCCTTTGGGCTGGAAGGTGGTGGGGCCGAGCCCCATCCCCTTCGCCG
AGGGCTACCCCGTCCCCGAGGCCCTGGACGAGGCGGGGATGGCGCGGGTCCTCGAGGCCTTCGTGGAGGGGGCCAAGCGG
GCCCTCAGGGCGGGGTTTTTGGTGGTGGAGCTCCACATGGCCCACGGCTACCTCCTCTCCTCCTTCCTCTCGCCCCTTGC
CAACCGGCGGGAGGACGCCTACGGGGGAAGCCGGGAGAACCGCATGCGCTTCCCCCTGGAGGTGGCGAGGGCGGTGCGGG
AGGCTATCCCCCCTGAGCTGCCCCTCTTCGTGCGGGTCTCGGCCACGGACTGGGCGGAAGGGGGGTGGGGCCTCGAGGAC
ACCCTGGCCTTCGCCGAACGGCTCAAGGCCCTGGGGGTGGACCTCCTGGACCTCTCCTCGGGCGGGGTGGTGCCGGGGGT
GAGGGTCCCCGTGGCCCCGGGCTTCCAGGTCCCCTTCGCCGACGCGGTGCGCAAGCGGGTGGGGATGCCGACGGGGGCGG
TGGGCCTCCTCACCACCCCCGAGCAGGCGGAGACCGTCCTCCAGGCGGGAAGCGCCGACCTGGTGCTTCTGGGCCGGGTC
CTCCTCCGGGACCCCTACTTCCCCCTGAAGGCGGCCAAGGCCCTCGGGGCGGAGGCCCCCGTGCCCCCGCAGTACCAGAG
GGCCTTTTAA

Upstream 100 bases:

>100_bases
AAAAGCGCTTCTTCACGGTATCACCTCCATAGGGTTCTTCTTGGAAAGGCTTCCAGAGCCACGCCCTCATTCTACAAGGA
CCTCCGGGGATAATGGTCCC

Downstream 100 bases:

>100_bases
GTACCCCACCGGGGCTTTCGGGGCTCCCACGTGGCGGGCGGACGCTGAGCGCGCTTGGCGGGGGCGCCCGGCCCGCTACC
GCCCCTGGAGGAGGTCCAGA

Product: NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MGLLFTPLELRGLRLKNRLAMSPMCQYSATEGGEVTDWHLLHYPTRALGGVGLVIVEATAVLPEGRISPFDLGIWSEDHL
PGLRELARRIREAGAVPGIQLAHAGRKAGTARPWEGGRPLGWKVVGPSPIPFAEGYPVPEALDEAGMARVLEAFVEGAKR
ALRAGFLVVELHMAHGYLLSSFLSPLANRREDAYGGSRENRMRFPLEVARAVREAIPPELPLFVRVSATDWAEGGWGLED
TLAFAERLKALGVDLLDLSSGGVVPGVRVPVAPGFQVPFADAVRKRVGMPTGAVGLLTTPEQAETVLQAGSADLVLLGRV
LLRDPYFPLKAAKALGAEAPVPPQYQRAF

Sequences:

>Translated_349_residues
MGLLFTPLELRGLRLKNRLAMSPMCQYSATEGGEVTDWHLLHYPTRALGGVGLVIVEATAVLPEGRISPFDLGIWSEDHL
PGLRELARRIREAGAVPGIQLAHAGRKAGTARPWEGGRPLGWKVVGPSPIPFAEGYPVPEALDEAGMARVLEAFVEGAKR
ALRAGFLVVELHMAHGYLLSSFLSPLANRREDAYGGSRENRMRFPLEVARAVREAIPPELPLFVRVSATDWAEGGWGLED
TLAFAERLKALGVDLLDLSSGGVVPGVRVPVAPGFQVPFADAVRKRVGMPTGAVGLLTTPEQAETVLQAGSADLVLLGRV
LLRDPYFPLKAAKALGAEAPVPPQYQRAF
>Mature_348_residues
GLLFTPLELRGLRLKNRLAMSPMCQYSATEGGEVTDWHLLHYPTRALGGVGLVIVEATAVLPEGRISPFDLGIWSEDHLP
GLRELARRIREAGAVPGIQLAHAGRKAGTARPWEGGRPLGWKVVGPSPIPFAEGYPVPEALDEAGMARVLEAFVEGAKRA
LRAGFLVVELHMAHGYLLSSFLSPLANRREDAYGGSRENRMRFPLEVARAVREAIPPELPLFVRVSATDWAEGGWGLEDT
LAFAERLKALGVDLLDLSSGGVVPGVRVPVAPGFQVPFADAVRKRVGMPTGAVGLLTTPEQAETVLQAGSADLVLLGRVL
LRDPYFPLKAAKALGAEAPVPPQYQRAF

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=339, Percent_Identity=27.7286135693215, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787939, Length=364, Percent_Identity=28.2967032967033, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=305, Percent_Identity=30.1639344262295, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=294, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=342, Percent_Identity=28.6549707602339, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=235, Percent_Identity=31.4893617021277, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=319, Percent_Identity=28.5266457680251, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=330, Percent_Identity=27.5757575757576, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=347, Percent_Identity=29.1066282420749, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325086, Length=226, Percent_Identity=27.8761061946903, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=31.1111111111111, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 37519; Mature: 37388

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLFTPLELRGLRLKNRLAMSPMCQYSATEGGEVTDWHLLHYPTRALGGVGLVIVEATA
CCCEECCHHHHCHHHHHHHHCCHHHHCCCCCCCCCCEEEEEECCHHHHCCCEEEEEEHHH
VLPEGRISPFDLGIWSEDHLPGLRELARRIREAGAVPGIQLAHAGRKAGTARPWEGGRPL
HCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCC
GWKVVGPSPIPFAEGYPVPEALDEAGMARVLEAFVEGAKRALRAGFLVVELHMAHGYLLS
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHH
SFLSPLANRREDAYGGSRENRMRFPLEVARAVREAIPPELPLFVRVSATDWAEGGWGLED
HHHHHHHHCCHHHCCCCCCCCEECCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHH
TLAFAERLKALGVDLLDLSSGGVVPGVRVPVAPGFQVPFADAVRKRVGMPTGAVGLLTTP
HHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECC
EQAETVLQAGSADLVLLGRVLLRDPYFPLKAAKALGAEAPVPPQYQRAF
HHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHCCC
>Mature Secondary Structure 
GLLFTPLELRGLRLKNRLAMSPMCQYSATEGGEVTDWHLLHYPTRALGGVGLVIVEATA
CCEECCHHHHCHHHHHHHHCCHHHHCCCCCCCCCCEEEEEECCHHHHCCCEEEEEEHHH
VLPEGRISPFDLGIWSEDHLPGLRELARRIREAGAVPGIQLAHAGRKAGTARPWEGGRPL
HCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCC
GWKVVGPSPIPFAEGYPVPEALDEAGMARVLEAFVEGAKRALRAGFLVVELHMAHGYLLS
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHH
SFLSPLANRREDAYGGSRENRMRFPLEVARAVREAIPPELPLFVRVSATDWAEGGWGLED
HHHHHHHHCCHHHCCCCCCCCEECCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHH
TLAFAERLKALGVDLLDLSSGGVVPGVRVPVAPGFQVPFADAVRKRVGMPTGAVGLLTTP
HHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECC
EQAETVLQAGSADLVLLGRVLLRDPYFPLKAAKALGAEAPVPPQYQRAF
HHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA