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The map label for this gene is qorA [H]

Identifier: 55980122

GI number: 55980122

Start: 147827

End: 148786

Strand: Reverse

Name: qorA [H]

Synonym: TTHA0153

Alternate gene names: 55980122

Gene position: 148786-147827 (Counterclockwise)

Preceding gene: 55980126

Following gene: 55980121

Centisome position: 8.04

GC content: 71.67

Gene sequence:

>960_bases
ATGCGGGCCATACGGGTGCACGAGGTGGGCGGACCGGAGGTCTTGCGGCTCGAGGAGCTTCCTGTCCCGGAGCCTGGGCC
CGGGGAGGTCCTGGTGAGGCTTCTCGCCATCGGGGTGAACTTCATTGACACCTACAAGCGGAAGGGCCTCTACCCCGTGC
CCGCCCCCTTCACCCTGGGGGAGGAGGGGGCCGGGGTGGTGGAGAAGGTGGGGGAAGGCGTGGTGGGGGTGAGGCCCGGG
GACCGGGTGGCCTTCGCCAACGTGCAGGGGGCCTACGCCGAGTACCTGGTGGTCCCGGCGGAGAGGCTCGTCCCCGTCCC
CGAGGGGCTGGACCCGAAGCTCGCCGCCGCGGCCCTCCTCCAGGGGATGACGGTCCACTACCTCCTCAAGAGCACCTACC
CCGTGGCCCCCGGGGACCAGGTCCTGGTGCACGCGGGAGCCGGGGGGGTGGGGCAGCTCCTCATCCAGTGGGCCAAGCGC
CTTGGGGCCACGGTCTACGCCACGGCCAGCACCGAGGAGAAGCGCGGGCTCTGCCTCCAGGCGGGGGCCGACTACGCCTT
GCCCTACGAGGGCTTCGCCGAGGCGGTGAAGGCCCTCTCGGGGGGCGGGGTGGACGTGGTCTACGACGGGGTGGGGAAGG
ACACCTTCCTGGGTAGCCTTGCGGCCCTAAGGCCCCGGGGGATGCTCGTCCTCTTCGGCCAGTCCTCGGGGCCGGTGCCG
CCCCAGGACCCGCAGATCCTGAACCGCATGGGGAGCCTCTTCCTTACCCGCCCCACCCTCCACCACTACACGGCAAGCCG
CAAGGAGCTCCTCTTTCGGGCGGGGGAGGTCTTCCGGGGGGTGCTGGAGGGGTGGCTCAAGGTGCGCATCGGGGCCGAGT
TCCCCCTGGAAAACGCCCGGGAGGCCCACGAGGCCCTCGAGGGCCGGAGGACCACGGGCAAGGTCCTCCTCCTGCCCTAG

Upstream 100 bases:

>100_bases
GCTTGGCGTTCATGTTCACCTCCGCCAATAACTTTGTAGTACAAAGTTATTGGTGCGTCAAGGGGTGGCCTCGAGCCCGC
CCGCAAGGTAGACTCTCCCC

Downstream 100 bases:

>100_bases
GCCGGGGTAACCGGGCACACTTTTCCGGAAGCGGCGTGGTATACTATGGTCCGTTCCAAGGGCTTATGTGACCACGCCTT
GCGCGGTGCGCCGTCTTCCC

Product: NADPH:quinone reductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRAIRVHEVGGPEVLRLEELPVPEPGPGEVLVRLLAIGVNFIDTYKRKGLYPVPAPFTLGEEGAGVVEKVGEGVVGVRPG
DRVAFANVQGAYAEYLVVPAERLVPVPEGLDPKLAAAALLQGMTVHYLLKSTYPVAPGDQVLVHAGAGGVGQLLIQWAKR
LGATVYATASTEEKRGLCLQAGADYALPYEGFAEAVKALSGGGVDVVYDGVGKDTFLGSLAALRPRGMLVLFGQSSGPVP
PQDPQILNRMGSLFLTRPTLHHYTASRKELLFRAGEVFRGVLEGWLKVRIGAEFPLENAREAHEALEGRRTTGKVLLLP

Sequences:

>Translated_319_residues
MRAIRVHEVGGPEVLRLEELPVPEPGPGEVLVRLLAIGVNFIDTYKRKGLYPVPAPFTLGEEGAGVVEKVGEGVVGVRPG
DRVAFANVQGAYAEYLVVPAERLVPVPEGLDPKLAAAALLQGMTVHYLLKSTYPVAPGDQVLVHAGAGGVGQLLIQWAKR
LGATVYATASTEEKRGLCLQAGADYALPYEGFAEAVKALSGGGVDVVYDGVGKDTFLGSLAALRPRGMLVLFGQSSGPVP
PQDPQILNRMGSLFLTRPTLHHYTASRKELLFRAGEVFRGVLEGWLKVRIGAEFPLENAREAHEALEGRRTTGKVLLLP
>Mature_319_residues
MRAIRVHEVGGPEVLRLEELPVPEPGPGEVLVRLLAIGVNFIDTYKRKGLYPVPAPFTLGEEGAGVVEKVGEGVVGVRPG
DRVAFANVQGAYAEYLVVPAERLVPVPEGLDPKLAAAALLQGMTVHYLLKSTYPVAPGDQVLVHAGAGGVGQLLIQWAKR
LGATVYATASTEEKRGLCLQAGADYALPYEGFAEAVKALSGGGVDVVYDGVGKDTFLGSLAALRPRGMLVLFGQSSGPVP
PQDPQILNRMGSLFLTRPTLHHYTASRKELLFRAGEVFRGVLEGWLKVRIGAEFPLENAREAHEALEGRRTTGKVLLLP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=34.0490797546012, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=34.0490797546012, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI194239676, Length=323, Percent_Identity=34.0557275541796, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=31.8327974276527, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=30.9248554913295, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=32.5373134328358, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=32.5373134328358, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28557745, Length=270, Percent_Identity=33.7037037037037, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI156627571, Length=352, Percent_Identity=28.6931818181818, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI197927207, Length=194, Percent_Identity=30.4123711340206, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=44.8916408668731, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87081918, Length=273, Percent_Identity=28.9377289377289, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787863, Length=294, Percent_Identity=25.5102040816327, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=238, Percent_Identity=32.3529411764706, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17556000, Length=244, Percent_Identity=30.327868852459, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=214, Percent_Identity=30.3738317757009, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71988145, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=270, Percent_Identity=29.2592592592593, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=325, Percent_Identity=37.2307692307692, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6323961, Length=351, Percent_Identity=26.2108262108262, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=311, Percent_Identity=27.6527331189711, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=338, Percent_Identity=26.3313609467456, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33997; Mature: 33997

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIRVHEVGGPEVLRLEELPVPEPGPGEVLVRLLAIGVNFIDTYKRKGLYPVPAPFTLG
CCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EEGAGVVEKVGEGVVGVRPGDRVAFANVQGAYAEYLVVPAERLVPVPEGLDPKLAAAALL
CCCCHHHHHHCCCEEEECCCCEEEEEECCCCCHHEEEECHHHCCCCCCCCCHHHHHHHHH
QGMTVHYLLKSTYPVAPGDQVLVHAGAGGVGQLLIQWAKRLGATVYATASTEEKRGLCLQ
HCCHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCCEEEE
AGADYALPYEGFAEAVKALSGGGVDVVYDGVGKDTFLGSLAALRPRGMLVLFGQSSGPVP
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCC
PQDPQILNRMGSLFLTRPTLHHYTASRKELLFRAGEVFRGVLEGWLKVRIGAEFPLENAR
CCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
EAHEALEGRRTTGKVLLLP
HHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure
MRAIRVHEVGGPEVLRLEELPVPEPGPGEVLVRLLAIGVNFIDTYKRKGLYPVPAPFTLG
CCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EEGAGVVEKVGEGVVGVRPGDRVAFANVQGAYAEYLVVPAERLVPVPEGLDPKLAAAALL
CCCCHHHHHHCCCEEEECCCCEEEEEECCCCCHHEEEECHHHCCCCCCCCCHHHHHHHHH
QGMTVHYLLKSTYPVAPGDQVLVHAGAGGVGQLLIQWAKRLGATVYATASTEEKRGLCLQ
HCCHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCCEEEE
AGADYALPYEGFAEAVKALSGGGVDVVYDGVGKDTFLGSLAALRPRGMLVLFGQSSGPVP
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCC
PQDPQILNRMGSLFLTRPTLHHYTASRKELLFRAGEVFRGVLEGWLKVRIGAEFPLENAR
CCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
EAHEALEGRRTTGKVLLLP
HHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]