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The map label for this gene is degP1 [H]

Identifier: 55980068

GI number: 55980068

Start: 99487

End: 100533

Strand: Direct

Name: degP1 [H]

Synonym: TTHA0099

Alternate gene names: 55980068

Gene position: 99487-100533 (Clockwise)

Preceding gene: 55980067

Following gene: 55980069

Centisome position: 5.38

GC content: 74.02

Gene sequence:

>1047_bases
ATGCGGGCCCTTCTCCTCCTAGCCCTCCTCCTGACCCTGGTCCTGGGGCAGCGCCTGGTCGCCCCCGAGGAGGTGGCCCG
GGCCCAGGTGATCCAAAAGGCCCTCCCCGCGGTGGTGCGCGTCCAGGGAAGCGCCCTCTCCCCCGGAGGGGAGGACGTGG
TGGGCACGGGCTTCTTCGTGGGGCCGAGCCGGGTGGTCACCAACTACCACGTGATCCGGGACCTCAAGGACCTCACCGTC
CGGCTCGCCGACGGAAGGACGTTTCTCGCGGAGCGCTACGCCGTGGACCCCGGGATTGACCTCGCCCTCCTCACCGTCCG
GGGGGCGCGGGCCCCCGGGGTGCTGGCCTTCGCCCAGGTGGAGGCGAGGCGCCTCCCCCTGGGGATGGGGGTGGTCCTGG
TGGGCTTCCCCTACGGCCAGGGGCCCCTGGCCTCCTTCGGCATCCTCTCGGGGGTGGGCCCCCTGGAGGTTCCCCTGCCG
GACCCGAGCGTGGGAACCGAAGTGGGGGAGTACCTCTTCACCGACGCCCCCCTCACCGTGGGGAACTCGGGAAGCCCCCT
GCTCAACCTCCAGGGCGAGGTGGTGGGCCTCGTGGCCGACGTCATCGGGGGGCCGGCCGGGATCGGGGGCATCGGCGTGG
CCGTGCCCGGGGACCTGGTGGCCCAAAGCATCGCCGACCTGGAGCGCTTCGGCCTCCCCCAAAGGGGATGGCTCGGGGCC
AGCCTCATCAGCCTGGACGAACTCCCCCCCGTCCTCCTCCGGGCCGTGGGCCTCACCTCCACCCAGGGGGCGATGGTGGA
CCGGGTGGAGCCGGGAAGCCCCGCGGCCAGGGCCGGCCTCAAAGGGGCCCAGCGGGACACCCAGGGGAGGCTCCTCGCCC
TGGGGGACGTGATCCTGGCCGTGGACGGGGTGGCGGTGAAGGACAAGGCGGACGTCGTCCGCCTGGTGGCCCAGCGCCGC
CCCGGGGACCGGGTCCGCCTCACCCTCTGGCGGGACCGGAGGCGGCTGGAGGTCACCGTGGTCCTGATGGCCCGGCCGCG
GGAGTGA

Upstream 100 bases:

>100_bases
CTGAGGGAGCTCCGCCTAAGCCTCGTCCAGAGCCTGCAAAGGACCCTGGCCACGGGCCTGGACCTCCTCGGCATCCCCGC
GCCTGAGGTAATGTAAGCCC

Downstream 100 bases:

>100_bases
GGCCATGCCCACCTTGAAGGAGCTCTTCGCCCTCTTCGGGAAGGAAGCCCCGGAGGTGCCCGTCAGGGGCCTCACCCTGG
ACTCGAGGCGGGTGGAGCCC

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRALLLLALLLTLVLGQRLVAPEEVARAQVIQKALPAVVRVQGSALSPGGEDVVGTGFFVGPSRVVTNYHVIRDLKDLTV
RLADGRTFLAERYAVDPGIDLALLTVRGARAPGVLAFAQVEARRLPLGMGVVLVGFPYGQGPLASFGILSGVGPLEVPLP
DPSVGTEVGEYLFTDAPLTVGNSGSPLLNLQGEVVGLVADVIGGPAGIGGIGVAVPGDLVAQSIADLERFGLPQRGWLGA
SLISLDELPPVLLRAVGLTSTQGAMVDRVEPGSPAARAGLKGAQRDTQGRLLALGDVILAVDGVAVKDKADVVRLVAQRR
PGDRVRLTLWRDRRRLEVTVVLMARPRE

Sequences:

>Translated_348_residues
MRALLLLALLLTLVLGQRLVAPEEVARAQVIQKALPAVVRVQGSALSPGGEDVVGTGFFVGPSRVVTNYHVIRDLKDLTV
RLADGRTFLAERYAVDPGIDLALLTVRGARAPGVLAFAQVEARRLPLGMGVVLVGFPYGQGPLASFGILSGVGPLEVPLP
DPSVGTEVGEYLFTDAPLTVGNSGSPLLNLQGEVVGLVADVIGGPAGIGGIGVAVPGDLVAQSIADLERFGLPQRGWLGA
SLISLDELPPVLLRAVGLTSTQGAMVDRVEPGSPAARAGLKGAQRDTQGRLLALGDVILAVDGVAVKDKADVVRLVAQRR
PGDRVRLTLWRDRRRLEVTVVLMARPRE
>Mature_348_residues
MRALLLLALLLTLVLGQRLVAPEEVARAQVIQKALPAVVRVQGSALSPGGEDVVGTGFFVGPSRVVTNYHVIRDLKDLTV
RLADGRTFLAERYAVDPGIDLALLTVRGARAPGVLAFAQVEARRLPLGMGVVLVGFPYGQGPLASFGILSGVGPLEVPLP
DPSVGTEVGEYLFTDAPLTVGNSGSPLLNLQGEVVGLVADVIGGPAGIGGIGVAVPGDLVAQSIADLERFGLPQRGWLGA
SLISLDELPPVLLRAVGLTSTQGAMVDRVEPGSPAARAGLKGAQRDTQGRLLALGDVILAVDGVAVKDKADVVRLVAQRR
PGDRVRLTLWRDRRRLEVTVVLMARPRE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=305, Percent_Identity=27.5409836065574, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI24308541, Length=334, Percent_Identity=27.5449101796407, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7019477, Length=303, Percent_Identity=31.6831683168317, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI22129776, Length=318, Percent_Identity=25.1572327044025, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1789629, Length=340, Percent_Identity=32.9411764705882, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786356, Length=297, Percent_Identity=29.6296296296296, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789630, Length=326, Percent_Identity=30.9815950920245, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646839, Length=305, Percent_Identity=27.2131147540984, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 36389; Mature: 36389

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLLLALLLTLVLGQRLVAPEEVARAQVIQKALPAVVRVQGSALSPGGEDVVGTGFFV
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCEEECCEEE
GPSRVVTNYHVIRDLKDLTVRLADGRTFLAERYAVDPGIDLALLTVRGARAPGVLAFAQV
CCHHHHHHHHHHHHHHHHEEEEECCCEEEHHHHCCCCCCCEEEEEEECCCCCCEEEEEEH
EARRLPLGMGVVLVGFPYGQGPLASFGILSGVGPLEVPLPDPSVGTEVGEYLFTDAPLTV
HHHHCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
GNSGSPLLNLQGEVVGLVADVIGGPAGIGGIGVAVPGDLVAQSIADLERFGLPQRGWLGA
CCCCCCEEEECCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCH
SLISLDELPPVLLRAVGLTSTQGAMVDRVEPGSPAARAGLKGAQRDTQGRLLALGDVILA
HHHHHHCCCHHHHHHHCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCEEEECCEEEE
VDGVAVKDKADVVRLVAQRRPGDRVRLTLWRDRRRLEVTVVLMARPRE
ECCEEECCHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEEEECCCC
>Mature Secondary Structure
MRALLLLALLLTLVLGQRLVAPEEVARAQVIQKALPAVVRVQGSALSPGGEDVVGTGFFV
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCEEECCEEE
GPSRVVTNYHVIRDLKDLTVRLADGRTFLAERYAVDPGIDLALLTVRGARAPGVLAFAQV
CCHHHHHHHHHHHHHHHHEEEEECCCEEEHHHHCCCCCCCEEEEEEECCCCCCEEEEEEH
EARRLPLGMGVVLVGFPYGQGPLASFGILSGVGPLEVPLPDPSVGTEVGEYLFTDAPLTV
HHHHCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
GNSGSPLLNLQGEVVGLVADVIGGPAGIGGIGVAVPGDLVAQSIADLERFGLPQRGWLGA
CCCCCCEEEECCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCH
SLISLDELPPVLLRAVGLTSTQGAMVDRVEPGSPAARAGLKGAQRDTQGRLLALGDVILA
HHHHHHCCCHHHHHHHCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCEEEECCEEEE
VDGVAVKDKADVVRLVAQRRPGDRVRLTLWRDRRRLEVTVVLMARPRE
ECCEEECCHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]