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The map label for this gene is hrcA [H]

Identifier: 55980027

GI number: 55980027

Start: 56365

End: 57267

Strand: Direct

Name: hrcA [H]

Synonym: TTHA0058

Alternate gene names: 55980027

Gene position: 56365-57267 (Clockwise)

Preceding gene: 55980026

Following gene: 55980028

Centisome position: 3.05

GC content: 72.54

Gene sequence:

>903_bases
GTGACGGCCAGGCAGCGGCGGGTTCTCCACCTCTTGGTGGACGAGTACATCCAGACCAAGGCCCCGGTGCCCTCGGCGCG
GATCGCCGAGGGGCTGGGCCTTTCCCCCGCCCTGGCCCGGTACGAGCTCATCGCCCTCGAGGAGATGGGCTACCTCACCA
AGCCCCACGCCTCGGCGGGGAGGGTGCCCACGCGGCAGGGGTTCAGGCAGTACTCCCTCTCCCTCCTCCCCCCTAGGCCC
CTGCCGGAGGCCACCCGAAGGCGCCTGGAGCGGGCCTTGGAGGGGGCGAGAGAGCCCGAGGCCTTCCTGGTGAAGGTGGC
GGTGGGGCTTTCCGGCTACCCCGCCCTCCTCCGCCTCCAGCCCAGGCGGGCCCCCAAGCTCCTCCAGGTCCACCTCTCCC
CCCTCCCCGAGGGCACCCTGGCGGTGCTGGTCCTCGAGGGGGGGCGGGTCAAGGAGGTCCGGCTCCCCCTCGTCCTCCCC
CAGGAGACCCTTCGCCGGGCAGAGGAGGCCCTCACGGGGCCCTTGGAGACCCTGCCCGCGGCCCCCAAAGGCCTGGAGGA
CCTCTTCGCCCACCTCTCCCGGGCCCTCGCCTCCGGCTTCGCCCTCCGGTACCGGGAAGGCCTCTCCGAGGCCCTGAAGG
AGCCCGAGGCCAAGGACCCGGGGTTTTTGGAGCGGCTCGTGGCCCTTTACGAGGAAGGCGGCGAGGACCTCCTCACCCCG
CCCGGCAGGGTGGACGTGCGGGTGGGGGAGGTGGAGGGGCTCGCCCTGGTCCAGGCGGGCTTCCAGAAGGGGGAGTGGCT
GGGGGAGCTCACCCTGATCGGCCCCCTGCGCATGCGCTACGCCGAGGCCCTCTCCGTGGCCTTCAGCCTCTCCCAGGTCT
ATACTGGGCAGCATGCGGATTGA

Upstream 100 bases:

>100_bases
GTGGGGGACGGGAAGATCTTCGTCCTCCCGGTGGAGAAGGTCTACCGGATCCGCACCGGAGAGGAGGACGAGGCCGCGGT
GACCCCGGTACAATAAGGAT

Downstream 100 bases:

>100_bases
GGTCCGGCTCTTCGCCCTTTACCGGGAGCAGGCGGGGACGGACCGCCTCGCCCTGGAGCTCCCCGAGGGCGCCCGGGTGC
GGGAGGCCCAGAAAGCCCTG

Product: class I heat-shock genes transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTARQRRVLHLLVDEYIQTKAPVPSARIAEGLGLSPALARYELIALEEMGYLTKPHASAGRVPTRQGFRQYSLSLLPPRP
LPEATRRRLERALEGAREPEAFLVKVAVGLSGYPALLRLQPRRAPKLLQVHLSPLPEGTLAVLVLEGGRVKEVRLPLVLP
QETLRRAEEALTGPLETLPAAPKGLEDLFAHLSRALASGFALRYREGLSEALKEPEAKDPGFLERLVALYEEGGEDLLTP
PGRVDVRVGEVEGLALVQAGFQKGEWLGELTLIGPLRMRYAEALSVAFSLSQVYTGQHAD

Sequences:

>Translated_300_residues
MTARQRRVLHLLVDEYIQTKAPVPSARIAEGLGLSPALARYELIALEEMGYLTKPHASAGRVPTRQGFRQYSLSLLPPRP
LPEATRRRLERALEGAREPEAFLVKVAVGLSGYPALLRLQPRRAPKLLQVHLSPLPEGTLAVLVLEGGRVKEVRLPLVLP
QETLRRAEEALTGPLETLPAAPKGLEDLFAHLSRALASGFALRYREGLSEALKEPEAKDPGFLERLVALYEEGGEDLLTP
PGRVDVRVGEVEGLALVQAGFQKGEWLGELTLIGPLRMRYAEALSVAFSLSQVYTGQHAD
>Mature_299_residues
TARQRRVLHLLVDEYIQTKAPVPSARIAEGLGLSPALARYELIALEEMGYLTKPHASAGRVPTRQGFRQYSLSLLPPRPL
PEATRRRLERALEGAREPEAFLVKVAVGLSGYPALLRLQPRRAPKLLQVHLSPLPEGTLAVLVLEGGRVKEVRLPLVLPQ
ETLRRAEEALTGPLETLPAAPKGLEDLFAHLSRALASGFALRYREGLSEALKEPEAKDPGFLERLVALYEEGGEDLLTPP
GRVDVRVGEVEGLALVQAGFQKGEWLGELTLIGPLRMRYAEALSVAFSLSQVYTGQHAD

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR023120
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 32887; Mature: 32755

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARQRRVLHLLVDEYIQTKAPVPSARIAEGLGLSPALARYELIALEEMGYLTKPHASAG
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
RVPTRQGFRQYSLSLLPPRPLPEATRRRLERALEGAREPEAFLVKVAVGLSGYPALLRLQ
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCEEEEC
PRRAPKLLQVHLSPLPEGTLAVLVLEGGRVKEVRLPLVLPQETLRRAEEALTGPLETLPA
CCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCEECCHHHHHHHHHHHCCCHHHCCC
APKGLEDLFAHLSRALASGFALRYREGLSEALKEPEAKDPGFLERLVALYEEGGEDLLTP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PGRVDVRVGEVEGLALVQAGFQKGEWLGELTLIGPLRMRYAEALSVAFSLSQVYTGQHAD
CCCEEEEECCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TARQRRVLHLLVDEYIQTKAPVPSARIAEGLGLSPALARYELIALEEMGYLTKPHASAG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
RVPTRQGFRQYSLSLLPPRPLPEATRRRLERALEGAREPEAFLVKVAVGLSGYPALLRLQ
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCEEEEC
PRRAPKLLQVHLSPLPEGTLAVLVLEGGRVKEVRLPLVLPQETLRRAEEALTGPLETLPA
CCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCEECCHHHHHHHHHHHCCCHHHCCC
APKGLEDLFAHLSRALASGFALRYREGLSEALKEPEAKDPGFLERLVALYEEGGEDLLTP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PGRVDVRVGEVEGLALVQAGFQKGEWLGELTLIGPLRMRYAEALSVAFSLSQVYTGQHAD
CCCEEEEECCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA