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The map label for this gene is htpG

Identifier: 54297278

GI number: 54297278

Start: 1476668

End: 1478539

Strand: Direct

Name: htpG

Synonym: lpp1323

Alternate gene names: 54297278

Gene position: 1476668-1478539 (Clockwise)

Preceding gene: 54297277

Following gene: 54297282

Centisome position: 42.15

GC content: 37.55

Gene sequence:

>1872_bases
ATGGTTAGCAAGCAGCAAACTATGGGATTTCAAACAGAGGTAAAGCAAATGCTTCATTTGGTTGTGCATTCGCTTTATAG
CAACAAAGAGATTTTTCTTAGAGAATTAATTTCTAATGCTTCTGATGCCTTGGACAAGTTACGATTTTTAGCTTTATCAA
ACGGTTCATTGTTTGAAAATGATTCTGATTTGAAAATCAGCATCCAGATTAATGAAAAGCTTCAAACCATTACAATTAGC
GACAATGGGATTGGCTTAAGTTGGGAAGAGGCCGTAGAAAATTTGGGGACAATTGCAAAATCTGGAACAAAAGAATTTAT
TAGCCAATTAACTGGTGAACAGGCAAAAGATTCTCAACTCATAGGACAATTTGGAGTGGGCTTTTATTCCGCGTTTATCG
TTGCTGATAAAGTAACAGTTAAAAGTCGTCGTGCTGGATTACAACCTGAGGATGGAATTGTATGGGAGTCTAAGGGTGAT
GGTGAATTTACTATAGGATATGAAAAAAAATTGACCCGTGGTACAGAAATTACTTTGCACTTAAAACCTGAAAACGATGA
GTTTTTAAGTGATTGGCGTATTCGCGGTATTATTAGCAAATACTCTGATCATATTTGTTGGCCTATTTTGATGAAAAAGC
TTTCAGAGGAAGGCAAGGAATCAAAAGAATTTGAAACAGTAAACAAAGCGACGGCACTTTGGACACTACAGAAATCTGAA
ATTAGTGAAGAAGAATATAAGCAACTGTATAAACATATTTCTCATGATTACATGGATCCATTAACCTGGTCTCATAACCA
TGTTGAGGGAAAACACGAGTATATTACTTTGCTTTACATACCAGCCCATGCCCCATTTGATTTATGGCAGCATGAAGCCA
AACATGGACTAAAGCTTTATGTAAAGCGCGTATTTATTATGGATGAAGCGACACAATTTTTACCCCGATATTTACGATTT
GTAAAAGGGATTGTCGATGCCAGTGATTTACCGCTTAATATTTCTCGAGAAATATTACAGGATAATAAGCAAGTAGAGTC
AATTCGAGCTGCATGCACCAAACGTGTTTTGTCTATGCTTGAAAAAATGGCTACCAATGATAAAGAAACCTACCAGAAGT
TTTGGAATGAATTTGGACTTGTGCTAAAAGAAGGACCTATTGAGGATTTCGCTAATAAGGAAGCGATTGCCAAGTTGCTT
CGTTTTTCTACTACAGCAAGCGGTAGTGAGAAACAAGAAGTATCGCTGGAGGAATATGTTAGTCGCATGAAAGAAGGGCA
GGATAAAATTTATTATATTACAGCATCCAGCTACAATGCTGCTAAAAATAGCCCTCATTTGGAAATATTCAGGAAAAAGG
GAATTGAGGTATTATTGCTCAGTGATAAAGTCGATGAATGGCTTGTTGGCTATATGAATGAGTTTGCAGGCAAAAAACTG
CAATCAATTTCAAAAGGCAAGATTGAATTGGGGGATGATGAAACTTCCGAACAAATTAAAGAACAGGAAAAAACCCTGGA
GCCATTGATTAAGCATATTAAATCAGTTCTAAATGATCGAGTTAAAGATGTATTGCTGACTAATCGTCTTACTGATTCCC
CTGCATGTGTTGTTGCTGATGAGCAAGACATGGGATTGGAAATGCAAAGAATTTTACAAGCTGCGGGTCAACAGGTTCCA
GTGAGCAAGCCTATTTTTGAAATTAATCCGGATCATGCCCTGATTAAGCGGTTGCATGATATTCAGGATGATAACCAATT
CGAATTATGGGTTACTATGCTGTTTGAACAAGCTGTGTTGGCAGAAGGAGGGCAATTGGATAATCCCGCTGATTTTGTGA
ATCGGGTTAACAGACTCCTGGTTTCCTCCTAG

Upstream 100 bases:

>100_bases
GATTTTTCCTTTTTTAGCGCTATCCCCTTGAAATTTAATAGATCAACCCTATATGAGAAGTTAATTATTCGAACACAACT
ATTAACGGGGAGATTGTTTA

Downstream 100 bases:

>100_bases
TATTCCATTGGCCTGGCAATCAATCTCGGATGAGAACAAGTCATTATCCGGGATGAGCTGAACATAAAATAAAAAGGCTC
AAAAATGAGCCTTTTTATTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKLTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPILMKKLSEEGKESKEFETVNKATALWTLQKSE
ISEEEYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
VKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
QSISKGKIELGDDETSEQIKEQEKTLEPLIKHIKSVLNDRVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVP
VSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS

Sequences:

>Translated_623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKLTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPILMKKLSEEGKESKEFETVNKATALWTLQKSE
ISEEEYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
VKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
QSISKGKIELGDDETSEQIKEQEKTLEPLIKHIKSVLNDRVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVP
VSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS
>Mature_623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKLTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPILMKKLSEEGKESKEFETVNKATALWTLQKSE
ISEEEYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
VKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
QSISKGKIELGDDETSEQIKEQEKTLEPLIKHIKSVLNDRVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVP
VSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=36.984126984127, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=38.9705882352941, Blast_Score=279, Evalue=7e-75,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=38.9705882352941, Blast_Score=277, Evalue=3e-74,
Organism=Homo sapiens, GI20149594, Length=408, Percent_Identity=39.2156862745098, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI4507677, Length=214, Percent_Identity=45.3271028037383, Blast_Score=179, Evalue=7e-45,
Organism=Escherichia coli, GI1786679, Length=621, Percent_Identity=62.3188405797101, Blast_Score=816, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=39.6423248882265, Blast_Score=456, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=674, Percent_Identity=36.3501483679525, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=33.7962962962963, Blast_Score=323, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=37.4429223744292, Blast_Score=264, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6323840, Length=674, Percent_Identity=39.3175074183976, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6325016, Length=678, Percent_Identity=38.9380530973451, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=38.5401459854015, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=36.7107195301028, Blast_Score=403, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24586016, Length=642, Percent_Identity=35.3582554517134, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_LEGPA (Q5X5J7)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123647.1
- ProteinModelPortal:   Q5X5J7
- SMR:   Q5X5J7
- STRING:   Q5X5J7
- GeneID:   3117217
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1323
- LegioList:   lpp1323
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   LPNE297246:LPP1323-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71107; Mature: 71107

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFEN
CCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKLTRGTEITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEHHHHCCCCCEEEEE
LKPENDEFLSDWRIRGIISKYSDHICWPILMKKLSEEGKESKEFETVNKATALWTLQKSE
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHH
ISEEEYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VKRVFIMDEATQFLPRYLRFVKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSML
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYV
HHHHCCCHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHCCCCCCCHHCCCHHHHH
SRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
HHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
QSISKGKIELGDDETSEQIKEQEKTLEPLIKHIKSVLNDRVKDVLLTNRLTDSPACVVAD
HHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
EQDMGLEMQRILQAAGQQVPVSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVL
CCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEGGQLDNPADFVNRVNRLLVSS
HCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFEN
CCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKLTRGTEITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEHHHHCCCCCEEEEE
LKPENDEFLSDWRIRGIISKYSDHICWPILMKKLSEEGKESKEFETVNKATALWTLQKSE
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHH
ISEEEYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VKRVFIMDEATQFLPRYLRFVKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSML
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYV
HHHHCCCHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHCCCCCCCHHCCCHHHHH
SRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
HHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
QSISKGKIELGDDETSEQIKEQEKTLEPLIKHIKSVLNDRVKDVLLTNRLTDSPACVVAD
HHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
EQDMGLEMQRILQAAGQQVPVSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVL
CCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEGGQLDNPADFVNRVNRLLVSS
HCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA