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The map label for this gene is ppa [H]

Identifier: 54295594

GI number: 54295594

Start: 3060515

End: 3061051

Strand: Reverse

Name: ppa [H]

Synonym: lpl2681

Alternate gene names: 54295594

Gene position: 3061051-3060515 (Counterclockwise)

Preceding gene: 54295597

Following gene: 54295593

Centisome position: 91.49

GC content: 38.73

Gene sequence:

>537_bases
ATGAGTTTAATGGAAATTCCGAGCGGTCGTGATGTTCCAAATGAAGTGAATGTGATCATAGAAATCCCCATGCACGGAGA
ACCTGTAAAGTATGAAGTTGATAAAAGAACTGGCGCTTTATTTGTAGATCGATTTATGACGACAGCAATGTTTTATCCAA
CGAATTACGGTTATATCCCGAATACTCTTTCAGAAGATGGGGATCCTGTGGATGTGTTGGTAATAACTCCTGTCCCTTTG
ATCAGTGGGGCTGTTATTTCATGTCGAGCTGTTGGCATGTTAAAGATGACAGATGAATCCGGAGTTGATGCAAAGATTTT
GGCTGTTCCAACAACCAAACTAAGTAAAATGTATCAATCCATGCAAACTTATCAAGATATTCCTCAGCATTTATTGTTAT
CTATCGAACATTTTTTTAAGCACTATAAAGACCTGGAAGAAGGTAAATGGGTTAAGGTCGAAGGCTGGGTAGGCCCAGAT
GCAGCTCGTGAGGAAATAACATCCAGTATTAACCGTTATAATCACATAAAAAAGTAA

Upstream 100 bases:

>100_bases
CTATTATACATTTCATTTATTAGATTGCGAACGCTTGTCTTTGCCTTTTGATGCGATTTTTCGCATAATATTACTTTTAT
TTATTATTAAGGGTGCGTAA

Downstream 100 bases:

>100_bases
AACAGTGACTTGAACTGTGCCAGGTGTTGGGCATTGCTCAGCACCACCCTTATATCTTTAGCTATAATAGCGGCATCATT
TCAGCCCCTACTACAAAACA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSLMEIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKRTGALFVDRFMTTAMFYPTNYGYIPNTLSEDGDPVDVLVITPVPL
ISGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQSMQTYQDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPD
AAREEITSSINRYNHIKK

Sequences:

>Translated_178_residues
MSLMEIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKRTGALFVDRFMTTAMFYPTNYGYIPNTLSEDGDPVDVLVITPVPL
ISGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQSMQTYQDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPD
AAREEITSSINRYNHIKK
>Mature_177_residues
SLMEIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKRTGALFVDRFMTTAMFYPTNYGYIPNTLSEDGDPVDVLVITPVPLI
SGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQSMQTYQDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPDA
AREEITSSINRYNHIKK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=62.2093023255814, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20077; Mature: 19946

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMEIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKRTGALFVDRFMTTAMFYPTNYGYIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
NTLSEDGDPVDVLVITPVPLISGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQS
CCCCCCCCCEEEEEECCCHHHCCCHHHHEEEEEEEECCCCCCCEEEEEECCHHHHHHHHH
MQTYQDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPDAAREEITSSINRYNHIKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLMEIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKRTGALFVDRFMTTAMFYPTNYGYIP
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
NTLSEDGDPVDVLVITPVPLISGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQS
CCCCCCCCCEEEEEECCCHHHCCCHHHHEEEEEEEECCCCCCCEEEEEECCHHHHHHHHH
MQTYQDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPDAAREEITSSINRYNHIKK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9423859 [H]