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The map label for this gene is dksA [H]

Identifier: 54295179

GI number: 54295179

Start: 2576798

End: 2577229

Strand: Direct

Name: dksA [H]

Synonym: lpl2259

Alternate gene names: 54295179

Gene position: 2576798-2577229 (Clockwise)

Preceding gene: 54295178

Following gene: 54295180

Centisome position: 77.02

GC content: 42.59

Gene sequence:

>432_bases
GTGAAAAACGATGCAATAGGAAATATGGGAATAGCGCCCTACCAAGAGACTGAGGGCGAGGAATATATGAATGAAAAACA
GCTGGCACATATAGAAAAAATATTGCTCGCTTGGCGCCAATCTTTAATGGAAGAAGTAGATCGTACTGTCTCGCACATGA
AAGATGAAGCAGCCAATTTCCCAGATCCTTCCGACAGAGCAAGCCAGGAAGAAGAGTTTAGCATTGAGCTGAGAACCCGC
GACAGGGAACGAAAACTCATTAAAAAAATCGAAGACGCTCTTGAGCGATTAAGAAATGAAGATTTTGGATATTGTGAAGC
CTGCGGAATCGAAATTGGCCTGAAACGTCTTGAAGCAAGACCTACTGCGACCTTATGCATAGATTGTAAAACTCTATCTG
AAATCAAGGAACGCCAAAATCAAGGTGCTTGA

Upstream 100 bases:

>100_bases
TAGCGATTTTGTATAAAACTCAGTTTCAGATACAGAATGAAATATAGGGTCTGGCAGGACAGGACAATTAATTGATAAAA
CCAAAGAGAGATTATACAAC

Downstream 100 bases:

>100_bases
TTCTTTCTTGCCTCTGAACATTAAACAATAAATTCCCGCCAGGCGGGAGTTTATTATTACAAGCAATCGATGTTTTTTAT
GTATTTTACCAATTATGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKNDAIGNMGIAPYQETEGEEYMNEKQLAHIEKILLAWRQSLMEEVDRTVSHMKDEAANFPDPSDRASQEEEFSIELRTR
DRERKLIKKIEDALERLRNEDFGYCEACGIEIGLKRLEARPTATLCIDCKTLSEIKERQNQGA

Sequences:

>Translated_143_residues
MKNDAIGNMGIAPYQETEGEEYMNEKQLAHIEKILLAWRQSLMEEVDRTVSHMKDEAANFPDPSDRASQEEEFSIELRTR
DRERKLIKKIEDALERLRNEDFGYCEACGIEIGLKRLEARPTATLCIDCKTLSEIKERQNQGA
>Mature_143_residues
MKNDAIGNMGIAPYQETEGEEYMNEKQLAHIEKILLAWRQSLMEEVDRTVSHMKDEAANFPDPSDRASQEEEFSIELRTR
DRERKLIKKIEDALERLRNEDFGYCEACGIEIGLKRLEARPTATLCIDCKTLSEIKERQNQGA

Specific function: Dosage-dependent suppressor of a dnaK deletion mutation. It suppressed not only the temperature-sensitive growth but also the filamentous phenotype of the dnaK deletion strain, while the defect of lambda growth is not suppressed [H]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=133, Percent_Identity=72.9323308270677, Blast_Score=212, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR020460
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 16535; Mature: 16535

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01102 ZF_DKSA_1 ; PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDAIGNMGIAPYQETEGEEYMNEKQLAHIEKILLAWRQSLMEEVDRTVSHMKDEAANF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDPSDRASQEEEFSIELRTRDRERKLIKKIEDALERLRNEDFGYCEACGIEIGLKRLEAR
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
PTATLCIDCKTLSEIKERQNQGA
CCCEEEECHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNDAIGNMGIAPYQETEGEEYMNEKQLAHIEKILLAWRQSLMEEVDRTVSHMKDEAANF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDPSDRASQEEEFSIELRTRDRERKLIKKIEDALERLRNEDFGYCEACGIEIGLKRLEAR
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
PTATLCIDCKTLSEIKERQNQGA
CCCEEEECHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]