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The map label for this gene is gpsA [H]

Identifier: 54295148

GI number: 54295148

Start: 2544285

End: 2545274

Strand: Direct

Name: gpsA [H]

Synonym: lpl2228

Alternate gene names: 54295148

Gene position: 2544285-2545274 (Clockwise)

Preceding gene: 54295147

Following gene: 54295151

Centisome position: 76.05

GC content: 44.44

Gene sequence:

>990_bases
ATGAATAAAAAAACCATTGCCATGTTAGGTGCCGGCTCCTGGGGCACTGCTGTCGCAATTCATTTAGCTAAAATAGGGCA
TAAAACGCTGCTGTGGAGTCATAACCCACAGCATGTTGCCCTCATGGCCGAACAGCATTCAAATCCAGCTTACCTTCCTG
GTATACCTTTTCCAGAGAATTTGATTCCTTCTGATAATTTAATTGAATGCGTTCAATCAGCGAATTATGTCATCATAGCA
GTTCCTTCTCATGCCTTTGCGGAAATAATCAATAAAATCCCTAAACCAACCCAAGGATTGGCGTGGCTTACGAAGGGTGT
TGATCCAGCGAGTCATGAATTATTAAGCCAACTGGTTGCCAGTCGATTTGGGGTTGATTTTCCCATAGCAGTTATTTCAG
GCCCATCGTTTGCCAAAGAAGTGGCTCGCTTCCTGCCTACAGCTCTCACTTTGGCCAGTAACAATACGAACTATCAAAAA
AAAATGCATCAACTATTTCATCACGACAACATTCGTGTCTATTTAAGTGATGATTTAATAGGCGTGCAATTATGTGGCGC
TGTTAAAAATATCCTGGCGATAGCCTGTGGAATCAGTGATGGCTTAGGGTATGGCGCTAATGCCAAGGCAGCGCTTATTA
CCCGTGGACTTGCTGAAATGACTCGTTTGGGATTAAGCATGGGAGCACGGCAAGATACTTTTCTAGGCTTGGCTGGTGTA
GGGGACTTGGTATTGACTTGTACAGATGATCAATCGCGCAATCGCCGCTTTGGATTGCTCTTGGGTCGTGAAGTGCCTAT
TCCTGAAGCCGAACACCAAATTGGCCAAGTAGTTGAAGGGAAACACAATGCCGCTCAAATTTGCGCTATAGCCAACAAAA
ATAGGGTGGAAATGCCAATTTGTGAGCAAATTAATGCGCTATTGCATGGTATTGTTCATGCCCAAGAGGCCGTGAACAAC
TTAATGAGTCGTCCCGCCAAGGAAGAATAA

Upstream 100 bases:

>100_bases
TTAGTACTCGCACCGATTAATTTTGATGCTTTATATATGCAGCAGCTGGAAGAAAAACAAAAAGCAACTGGAGCTAAAGA
CGAGACTGTTTCTCACTAAG

Downstream 100 bases:

>100_bases
CCTTTGCCCTTGCAAAGAATCATATTAAATTAGGTTTAGTGCACCAGGACACCAGGACGCAGGTGATACTAGTCGATTGT
CGACATTAACCCATAGCATC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDNLIECVQSANYVIIA
VPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQK
KMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNRVEMPICEQINALLHGIVHAQEAVNN
LMSRPAKEE

Sequences:

>Translated_329_residues
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDNLIECVQSANYVIIA
VPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQK
KMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNRVEMPICEQINALLHGIVHAQEAVNN
LMSRPAKEE
>Mature_329_residues
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDNLIECVQSANYVIIA
VPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQK
KMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNRVEMPICEQINALLHGIVHAQEAVNN
LMSRPAKEE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=349, Percent_Identity=31.5186246418338, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI33695088, Length=313, Percent_Identity=29.073482428115, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1790037, Length=335, Percent_Identity=47.1641791044776, Blast_Score=325, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI32564399, Length=355, Percent_Identity=28.4507042253521, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=27.3239436619718, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=364, Percent_Identity=27.7472527472527, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=364, Percent_Identity=27.7472527472527, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193210134, Length=347, Percent_Identity=25.0720461095101, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=309, Percent_Identity=27.5080906148867, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324513, Length=358, Percent_Identity=25.6983240223464, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI22026922, Length=294, Percent_Identity=27.2108843537415, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136202, Length=311, Percent_Identity=30.5466237942122, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136200, Length=311, Percent_Identity=30.5466237942122, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136204, Length=311, Percent_Identity=30.5466237942122, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI45551945, Length=269, Percent_Identity=26.0223048327138, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281362270, Length=264, Percent_Identity=26.1363636363636, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648969, Length=211, Percent_Identity=27.4881516587678, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 35437; Mature: 35437

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPEN
CCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCC
LIPSDNLIECVQSANYVIIAVPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVA
CCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
SRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLI
HHCCCCCCEEEECCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEECCCH
GVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNRVEMPI
CCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHH
CEQINALLHGIVHAQEAVNNLMSRPAKEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPEN
CCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCC
LIPSDNLIECVQSANYVIIAVPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVA
CCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
SRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLI
HHCCCCCCEEEECCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEECCCH
GVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNRVEMPI
CCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHH
CEQINALLHGIVHAQEAVNNLMSRPAKEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA