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The map label for this gene is grx [H]

Identifier: 54295146

GI number: 54295146

Start: 2543531

End: 2543785

Strand: Direct

Name: grx [H]

Synonym: lpl2226

Alternate gene names: 54295146

Gene position: 2543531-2543785 (Clockwise)

Preceding gene: 54295145

Following gene: 54295147

Centisome position: 76.02

GC content: 37.65

Gene sequence:

>255_bases
ATGAATGAAGTCATACTCTACACTACAGGCTATTGTCCTTATTGCATCAAAGCAAAAGAACTACTAGATAGAAAAAAGGT
TATCTATACCGAAATCCGCGTCGATTTAAAGCCTGAATTACGTGAAGAAATGATACAAAAAAGTGGCCGGCGTACAGTGC
CTCAAATTTTCATTAATGGCCAGGCAATTGGTGGCTGCGATGATTTATATGCACTGGAAGCCCAGGGAACATTAAATGAA
CTTTTAAAAAAATAG

Upstream 100 bases:

>100_bases
ATGAAAATCCGCAATCAAGGTTACCAACCCCTGGTTTTGAGTGGAGGAATTCAAGCCTGGCAAAATGCTGATCTTCCTTT
AGTGAAGGGTAAATGAACAG

Downstream 100 bases:

>100_bases
GAATAAAACATGACTGAACAACTGAATACCAATCAGCAAAATGATGAAGCTCAATTCATGATTCAACGAATCTATATCAA
AGATTTATCCTATGAAACAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MNEVILYTTGYCPYCIKAKELLDRKKVIYTEIRVDLKPELREEMIQKSGRRTVPQIFINGQAIGGCDDLYALEAQGTLNE
LLKK

Sequences:

>Translated_84_residues
MNEVILYTTGYCPYCIKAKELLDRKKVIYTEIRVDLKPELREEMIQKSGRRTVPQIFINGQAIGGCDDLYALEAQGTLNE
LLKK
>Mature_84_residues
MNEVILYTTGYCPYCIKAKELLDRKKVIYTEIRVDLKPELREEMIQKSGRRTVPQIFINGQAIGGCDDLYALEAQGTLNE
LLKK

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=57.8313253012048, Blast_Score=99, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9651; Mature: 9651

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVILYTTGYCPYCIKAKELLDRKKVIYTEIRVDLKPELREEMIQKSGRRTVPQIFING
CCCEEEEECCCCCCEECHHHHHHHHHEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECC
QAIGGCDDLYALEAQGTLNELLKK
CCCCCCCCEEEEECCCCHHHHHCC
>Mature Secondary Structure
MNEVILYTTGYCPYCIKAKELLDRKKVIYTEIRVDLKPELREEMIQKSGRRTVPQIFING
CCCEEEEECCCCCCEECHHHHHHHHHEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECC
QAIGGCDDLYALEAQGTLNELLKK
CCCCCCCCEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]