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The map label for this gene is dtpA [H]

Identifier: 54295042

GI number: 54295042

Start: 2423939

End: 2425420

Strand: Direct

Name: dtpA [H]

Synonym: lpl2122

Alternate gene names: 54295042

Gene position: 2423939-2425420 (Clockwise)

Preceding gene: 54295038

Following gene: 54295050

Centisome position: 72.45

GC content: 37.18

Gene sequence:

>1482_bases
ATGCCGCATGGAGTTACTGCGCTCTGCTTAATTCAGGCATTTTCGACTTTTTCATACGCTGTTCAATATTCTTCGCTCGC
ACTTTTTATTACCAAACAACTTGGAATTGCCAATTTATCTGCCAATAGTATAGTGGGCCTGTTTTTAAGTTTTAGCTATA
TTTTTCAACTAATTGGCGGTGTCATCGGAAGCCGTTTTATAAGTAACAGACTACTATTTGTTACAACTATTCTTATTCAA
AATATGGGTTTATTCTTTTTAGCGCAAGCAAATCCTTCCTTGCTTAACATAGGCCTAAGTTTGTTTATGGTAGGTTCTGG
TTTGAATGTTACTTCCAGCAACAGCATGCTTACTCAATGTTTCATACCACAGGATGATCGCAGGGAAAGCGCATTTTTTC
TCAGTTATGCCGGCATGAATGTCGGTTATTGCATAGGTTATATAGCCTGCGGTTTTTTTGATTACTCCAACCAGTATCAA
TATTTGTTCTATGCAAGCATCCTGACTAACTCCATTGCTTTATTGATTATTATCAAAAACTGGGCCTACCTTGGCGATAA
AAATTTTCCATTACCCAATCTCACTAAACGAAACTGGTATTTCATAAAAAATATTCTGGCAATAGCATTCATTACACTCC
TTATTCCTTTTATGCGGGTATGTTTTGAGTTTGCAAATTTTTGTAATGGATTGGTAATAATTACCTGTTTATTCATGTTT
CTTATTATCTTTATCCTGGGGTTAAAACAAAAATCCTCCTCCGACAGAAAAAAAATGATGGCCTATTTAATTTTGGCAAT
CAGTTCGGTTTTATTTTGGATGATTTATCTAACTGGCCCAATGGGCGTAACTCTTTTTGTCAAAAATAATGTGGATAAGC
ATCTTTTCAGCTTTGAATTGGCTACTCAATGGATAAAAAATATTAATCCCGTGGTCATTATTTTAGGAGCACCAATCATG
GCCATGCTCATTAACAAATTAAAAGCAAAAGGTTTTCATGTCTCTGTTCCTGTGCAATTTTCCTGTTCCTTCGTGTTTTT
AGCCCTGTCCTTTTTATGCCTTATCTTTGGAATTATTTGTTCAAATTCCTATGGGTATATCAGCGTATACTGGATCATAG
GCCATCATATCTTGCAAGGAATGTCTGAGTTGCTTCTTGGCCCTGTTGGCTATGCGTTAATTGGGAGAATAGCTCCCCCA
AAACTACAAGGGATTTTAATGGGCACCTGGATGCTGGTTACAGGGGTCGCAGCCTCTTTTTCCCAGTATTTCTCCAATGC
CATGGTGCAATCAGAATCTGTAGCCCCCCTAACTACAAATCAGGATTTTCTAACTGCATTTAAGCAATTGGGGCTTTGGT
CTTTACTCTGTGCTGCCTTGTTATATTTTGTTTCAGGTAAATTAACCAGGATAATAAATGGTATAAAAGACAATAAATCA
GTTAATGAGAGCAAGGCTCTCCCCATGCCTTACTCTAACTAA

Upstream 100 bases:

>100_bases
ATAGCAAGTTGTTACATTCTTGAAGGCAACTGATTATTGATGGTAAAGTCTATTCTCATAAAATCAGCCAAAATGTTTGA
TGATTAAAATAATTCGAGAA

Downstream 100 bases:

>100_bases
TCATTTAAAAATCCAAAGTATGGCTTTGCTCATCAGTTTCTTCCAAACGAGCAGAAACATCCATGTAAATTTTTGGATTG
TACTGATACAAACGTAAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MPHGVTALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLLFVTTILIQ
NMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQ
YLFYASILTNSIALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVVIILGAPIM
AMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIICSNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPP
KLQGILMGTWMLVTGVAASFSQYFSNAMVQSESVAPLTTNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRIINGIKDNKS
VNESKALPMPYSN

Sequences:

>Translated_493_residues
MPHGVTALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLLFVTTILIQ
NMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQ
YLFYASILTNSIALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVVIILGAPIM
AMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIICSNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPP
KLQGILMGTWMLVTGVAASFSQYFSNAMVQSESVAPLTTNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRIINGIKDNKS
VNESKALPMPYSN
>Mature_492_residues
PHGVTALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLLFVTTILIQN
MGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQY
LFYASILTNSIALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMFL
IIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVVIILGAPIMA
MLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIICSNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPPK
LQGILMGTWMLVTGVAASFSQYFSNAMVQSESVAPLTTNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRIINGIKDNKSV
NESKALPMPYSN

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=477, Percent_Identity=25.5765199161426, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789911, Length=474, Percent_Identity=25.9493670886076, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790572, Length=478, Percent_Identity=25.3138075313808, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786927, Length=480, Percent_Identity=22.9166666666667, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54855; Mature: 54724

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGVTALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIGSRFISNRLLFVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQC
HHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHEEECCCCCCCCCCCEEEEE
FIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQYLFYASILTNSIALLIIIKN
ECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEHEEHHHHHHCCCEEEEEEEC
WAYLGDKNFPLPNLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFEL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
ATQWIKNINPVVIILGAPIMAMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIIC
HHHHHHCCCCEEEEECHHHHHHHHHHHHCCCEEEEEEHEECHHHHHHHHHHHHHHHHHHH
SNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPPKLQGILMGTWMLVTGVAASF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SQYFSNAMVQSESVAPLTTNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRIINGIKDNKS
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
VNESKALPMPYSN
CCCCCCCCCCCCC
>Mature Secondary Structure 
PHGVTALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIGSRFISNRLLFVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQC
HHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHEEECCCCCCCCCCCEEEEE
FIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQYLFYASILTNSIALLIIIKN
ECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEHEEHHHHHHCCCEEEEEEEC
WAYLGDKNFPLPNLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFEL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
ATQWIKNINPVVIILGAPIMAMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIIC
HHHHHHCCCCEEEEECHHHHHHHHHHHHCCCEEEEEEHEECHHHHHHHHHHHHHHHHHHH
SNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPPKLQGILMGTWMLVTGVAASF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SQYFSNAMVQSESVAPLTTNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRIINGIKDNKS
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
VNESKALPMPYSN
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]