Click here to switch to the map view.

The map label for this gene is yheS [H]

Identifier: 54294753

GI number: 54294753

Start: 2046826

End: 2048676

Strand: Direct

Name: yheS [H]

Synonym: lpl1830

Alternate gene names: 54294753

Gene position: 2046826-2048676 (Clockwise)

Preceding gene: 54294752

Following gene: 54294758

Centisome position: 61.18

GC content: 38.79

Gene sequence:

>1851_bases
ATGCTTACATTGCGTCAAATTACTTTATCCAGAGGAGATAAAATTTTACTCGATAAGGTCAATGTCAGTCTTTATGAAAA
ACAAAAAATTGGCCTTATCGGTCATAATGGATGTGGAAAATCAACATTATTTGATTTTCTTTTAGGTCAATTATCTCCTG
ATACTGGAGAATATCTAATTAATCCACAACTCAGTATCAGTCATTTGTCTCAACACATACCTGATAGCAATGAAAAAGCT
TTGGATTTTGTTCTTGCCGGAGATCAACAATACATTAAATTGCTAAAGCGCCTTTCAGAAGCTGAAAAAAACGGCGATGA
TGCAGAAGTTTTGCAATGCCACGAGGAACTCTCTCATACTGGTGGTTACAGTAAGCCCGCGCAAGCAGCAGTTATTATGT
CTGGCTTAGGATTTAGTGGAAATCAACAGCAAGAGCCCGTTAACAGCTTTTCTGGTGGCTGGAGAATGCGCTTAAATCTT
GCTCGGTGCTTAATGAAACCCGCCGATTTACTCTTGCTTGATGAACCAACAAACCATTTAGACATGGAAGCCATCTTCTG
GCTGGAACGCTATTTAAAACAAAGCCCAAGTACTATTATTCTTATTTCACACGATAGAGAATTTCTTGATGCCTTTGTTA
CTCATATATTACATATAGAAAATCGTAATCTGACACTTTATTCAGGAAACTATAGCAGCTTTGAAAAAATTCATGCGCAA
CAACTGGCTCTACAACAAGCAATGCATGAAAAGCAACAAACCAAAATCAAACATATGATGACTTTTGTAACTCGTTTTAA
AGCGAAAGCAACCAAGGCCAAACAAGCGCAAAGTCGAATGAAAGCTATAGAAAAGATGGAAATAATCGCAGCAGCCCAGG
CTGACTCCCCTTTTTCTTTTGATTTTTTCCCTTGTCCCCGGGCAGGAAATCCTTTAATTCAATGCAATCAAGTTGATGCA
GGATATATCAATCATCCTCCGATTTTGAAAAAAATCAAACTCTCTCTTAATCCCGGCGATAGAATTGCGCTACTGGGACC
TAACGGTGAAGGAAAATCAACCTTAATTAAAACGCTTACAGCAGATTTGTCCGTATTAAGTGGAGATATTCATCGTTCTC
CACACTTACAAATAGGCTACTACGCTCAGCATCAACTTGAGCAATTAGACTGTAAATTAAGTCCGGTAGAAACACTGCAA
ACTCTCTCGCCAGAGGTAAGAGAACAAACCATACGGGATTTTTTAGGTGGGTTTAATTTCAGAGGGGACATGGCGGTACA
ATCCATTCAGCACTTTTCAGGTGGTGAAAAAGCCCGCCTGGCATTAGCAAGACTGGTTTGGCTAAAACCCAACCTTCTTT
TGCTGGATGAGCCAACAAACCATTTGGATCTTGGAATGCGCTCAGCAATTGAATTAGCGCTGCAAACTTATGAGGGTGCC
TTAATTTTGATTTCGCATGACCGCCATTTGTTAAAATCAAGTGTGGATAATTTTTATCTTATTTATCAAGGAAAAGTACA
ACCATTTGAAGGGGATCTTGATGATTACTATCTATGGCTGCAAACCAGAAATTCAGAAAAGGAATCCAAATTAGCTACCT
CCCCAAATGAATATAAAGAAAGAAAAAGCTATCAAAACAAATTAAAAAAGCTGGAGCAACTCATTGAGCACTATCAGAAT
CAATTGCGCCTCCTTGATAAGCAGCTAGCTGACGTTTCTCTGTATGAAGACACAAAGCAGAAAAACAAATTGGATAATCT
TTTGATGGAACGAGATATCGCTCATTCTTCTTTAATGAAGACAGAAGAAGAGTGGTTAGGAATATGTCACGCCCTGGAAA
ACCTGGAGTAA

Upstream 100 bases:

>100_bases
TTTTAAACTTATGCAAATATTCAACTCGCTTACATCATCAATAGGAAGCTTAAGCTAATTTATGATAAAATGACTAATTA
GTTCAAGCTTACGGTATAAC

Downstream 100 bases:

>100_bases
GTAATAGGTTCTGCTGATCAATACCATTTAACCTTGTAACTGTTCCAACATGGCTTTTGCTGCCAACTGCTCAGCTTTTC
TTCTATTAGGCCCTGTGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLINPQLSISHLSQHIPDSNEKA
LDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNL
ARCLMKPADLLLLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNYSSFEKIHAQ
QLALQQAMHEKQQTKIKHMMTFVTRFKAKATKAKQAQSRMKAIEKMEIIAAAQADSPFSFDFFPCPRAGNPLIQCNQVDA
GYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLTADLSVLSGDIHRSPHLQIGYYAQHQLEQLDCKLSPVETLQ
TLSPEVREQTIRDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIELALQTYEGA
LILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKERKSYQNKLKKLEQLIEHYQN
QLRLLDKQLADVSLYEDTKQKNKLDNLLMERDIAHSSLMKTEEEWLGICHALENLE

Sequences:

>Translated_616_residues
MLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLINPQLSISHLSQHIPDSNEKA
LDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNL
ARCLMKPADLLLLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNYSSFEKIHAQ
QLALQQAMHEKQQTKIKHMMTFVTRFKAKATKAKQAQSRMKAIEKMEIIAAAQADSPFSFDFFPCPRAGNPLIQCNQVDA
GYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLTADLSVLSGDIHRSPHLQIGYYAQHQLEQLDCKLSPVETLQ
TLSPEVREQTIRDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIELALQTYEGA
LILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKERKSYQNKLKKLEQLIEHYQN
QLRLLDKQLADVSLYEDTKQKNKLDNLLMERDIAHSSLMKTEEEWLGICHALENLE
>Mature_616_residues
MLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLINPQLSISHLSQHIPDSNEKA
LDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNL
ARCLMKPADLLLLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNYSSFEKIHAQ
QLALQQAMHEKQQTKIKHMMTFVTRFKAKATKAKQAQSRMKAIEKMEIIAAAQADSPFSFDFFPCPRAGNPLIQCNQVDA
GYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLTADLSVLSGDIHRSPHLQIGYYAQHQLEQLDCKLSPVETLQ
TLSPEVREQTIRDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIELALQTYEGA
LILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKERKSYQNKLKKLEQLIEHYQN
QLRLLDKQLADVSLYEDTKQKNKLDNLLMERDIAHSSLMKTEEEWLGICHALENLE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=534, Percent_Identity=36.7041198501873, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI27881506, Length=524, Percent_Identity=34.5419847328244, Blast_Score=306, Evalue=5e-83,
Organism=Homo sapiens, GI10947137, Length=524, Percent_Identity=34.5419847328244, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI10947135, Length=544, Percent_Identity=33.4558823529412, Blast_Score=252, Evalue=6e-67,
Organism=Homo sapiens, GI69354671, Length=544, Percent_Identity=33.4558823529412, Blast_Score=252, Evalue=6e-67,
Organism=Escherichia coli, GI1789751, Length=634, Percent_Identity=45.7413249211356, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=34.593572778828, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1787182, Length=636, Percent_Identity=29.7169811320755, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI2367384, Length=530, Percent_Identity=30, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788506, Length=541, Percent_Identity=23.8447319778189, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48995001, Length=525, Percent_Identity=23.4285714285714, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788165, Length=173, Percent_Identity=32.9479768786127, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786698, Length=199, Percent_Identity=29.1457286432161, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789864, Length=247, Percent_Identity=25.1012145748988, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787758, Length=190, Percent_Identity=26.8421052631579, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1787547, Length=200, Percent_Identity=27, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1787500, Length=212, Percent_Identity=24.5283018867925, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17553372, Length=528, Percent_Identity=36.3636363636364, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17555318, Length=514, Percent_Identity=35.6031128404669, Blast_Score=298, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI17559834, Length=542, Percent_Identity=31.1808118081181, Blast_Score=282, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17542146, Length=196, Percent_Identity=26.0204081632653, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=528, Percent_Identity=35.0378787878788, Blast_Score=325, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6320874, Length=525, Percent_Identity=32.3809523809524, Blast_Score=286, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6325030, Length=388, Percent_Identity=32.2164948453608, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324314, Length=400, Percent_Identity=29.75, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=403, Percent_Identity=29.5285359801489, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=37.0018975332068, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI24642252, Length=525, Percent_Identity=36.7619047619048, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI18859989, Length=525, Percent_Identity=36.7619047619048, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24641342, Length=536, Percent_Identity=32.089552238806, Blast_Score=289, Evalue=4e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69941; Mature: 69941

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLI
CCEEEEEHHCCCCEEEEEECCCEEECCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCEEE
NPQLSISHLSQHIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHT
CCCCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNLARCLMKPADLLLLDEPTNHL
CCCCCCHHHHHHEECCCCCCCCCCCCHHHCCCCEEEEHHHHHHHCCCCCEEEEECCCCCC
DMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNYSSFEKIHAQ
CHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHEEECCEEEEEECCCHHHHHHHHH
QLALQQAMHEKQQTKIKHMMTFVTRFKAKATKAKQAQSRMKAIEKMEIIAAAQADSPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
DFFPCPRAGNPLIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLT
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCHHHHHHHHH
ADLSVLSGDIHRSPHLQIGYYAQHQLEQLDCKLSPVETLQTLSPEVREQTIRDFLGGFNF
HHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCC
RGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIELALQTYEGA
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCE
LILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKE
EEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHCCCCCHHHHH
RKSYQNKLKKLEQLIEHYQNQLRLLDKQLADVSLYEDTKQKNKLDNLLMERDIAHSSLMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEEWLGICHALENLE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLI
CCEEEEEHHCCCCEEEEEECCCEEECCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCEEE
NPQLSISHLSQHIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHT
CCCCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNLARCLMKPADLLLLDEPTNHL
CCCCCCHHHHHHEECCCCCCCCCCCCHHHCCCCEEEEHHHHHHHCCCCCEEEEECCCCCC
DMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNYSSFEKIHAQ
CHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHEEECCEEEEEECCCHHHHHHHHH
QLALQQAMHEKQQTKIKHMMTFVTRFKAKATKAKQAQSRMKAIEKMEIIAAAQADSPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
DFFPCPRAGNPLIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLT
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCHHHHHHHHH
ADLSVLSGDIHRSPHLQIGYYAQHQLEQLDCKLSPVETLQTLSPEVREQTIRDFLGGFNF
HHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCC
RGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIELALQTYEGA
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCE
LILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKE
EEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHCCCCCHHHHH
RKSYQNKLKKLEQLIEHYQNQLRLLDKQLADVSLYEDTKQKNKLDNLLMERDIAHSSLMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEEWLGICHALENLE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]