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The map label for this gene is iolE [H]

Identifier: 54294539

GI number: 54294539

Start: 1787054

End: 1787950

Strand: Reverse

Name: iolE [H]

Synonym: lpl1615

Alternate gene names: 54294539

Gene position: 1787950-1787054 (Counterclockwise)

Preceding gene: 54294540

Following gene: 54294538

Centisome position: 53.44

GC content: 38.91

Gene sequence:

>897_bases
ATGGAAGTGAAGATGAGTATTCAACTTGGTATCGCACCAATTAATTGGTGCAATGATGATGATCCGAATTTAGGTAAAGA
CATTAGTTTTGAGCAATGTATTAACGAAATGGCTATGGCAGGCTATTCTGGCACTGAGTTGGGGAATAAATACCCACGAG
ATGTAAGAACGTTAAAGACTGCCTTGGAACAACGAGGTTTACAATTATCCAGTTCATGGTTTAGCACTTATTTTACTGAG
GCCAATGCTTTTGAAAAAACCGTATCAAGATTTCTTGAACACTTAAGCTTTATGCGCGCATTAGGTGCATCGTATATTAA
TGTTTGTGAATGCGGTCATGCTATTCAAGGCACTGATTTACCGATATTAAGTGCACATATTCCTCAATTTACTCAAGAGC
AATGGAGTTTATTGATTCAAGGGCTACATACCTTAGGCCGAATTGCTTACGACTTCAATATGAAGATCGTTTATCATTAC
CATGCAGGAACTGGGGTGTTTTGGGAGAAAGACATTGATTTTTTAATGACCAATACCAGTCCAAAGTTGGTTTCTCTATT
ACTTGACACAGGACATGCTGTCTTTTCAGGAATAGATCCGGTTAATTTAATAGATAAGTACGGTGATCGTATTTTGTATG
TTCATCTGAAAGACATTCGCCCTGAGGTCTTGAGACGAGTTGAAATGGAGAGACTCAGCTTTATGGATGCAGTAAGAAGA
GGGGTATTTACTGTGCCTGGTGATGGAGCAATTGATTTCATACCTATATGGGCAGGGCTGCAAAAACATCGCTATAATGG
ATGGATGATAGTGGAGGCGGAGCAGGATCCGGAAAAAGCACATCCTTTGGAATACGCCAAAAAAGCATATGATTATTTGC
ATTCATTTATTCATTAA

Upstream 100 bases:

>100_bases
GGTGGCGGGTTGGAGTTGCTGAGGTATCTCAATCAGAATCAGTGAGTAAAGCTTACCAAATGATGCGAGAGCAAATTGAA
ACAGTTAGACAATATTGAAG

Downstream 100 bases:

>100_bases
AGAAAGGCTGATGATTGAAGATTTAATAAAGCTTACTTTATTAAAAATAGCAGGGAAGCTTAAGAGTTATCTGTTTATAG
GCTGGGATCTGGTTAAGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MEVKMSIQLGIAPINWCNDDDPNLGKDISFEQCINEMAMAGYSGTELGNKYPRDVRTLKTALEQRGLQLSSSWFSTYFTE
ANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHY
HAGTGVFWEKDIDFLMTNTSPKLVSLLLDTGHAVFSGIDPVNLIDKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRR
GVFTVPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH

Sequences:

>Translated_298_residues
MEVKMSIQLGIAPINWCNDDDPNLGKDISFEQCINEMAMAGYSGTELGNKYPRDVRTLKTALEQRGLQLSSSWFSTYFTE
ANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHY
HAGTGVFWEKDIDFLMTNTSPKLVSLLLDTGHAVFSGIDPVNLIDKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRR
GVFTVPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH
>Mature_298_residues
MEVKMSIQLGIAPINWCNDDDPNLGKDISFEQCINEMAMAGYSGTELGNKYPRDVRTLKTALEQRGLQLSSSWFSTYFTE
ANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDLPILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHY
HAGTGVFWEKDIDFLMTNTSPKLVSLLLDTGHAVFSGIDPVNLIDKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRR
GVFTVPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 34029; Mature: 34029

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKMSIQLGIAPINWCNDDDPNLGKDISFEQCINEMAMAGYSGTELGNKYPRDVRTLKT
CCEEEEEEECCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ALEQRGLQLSSSWFSTYFTEANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGTGVFWEKDIDFLMTNTS
CHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEECCCCCEEECCCCEEEECCC
PKLVSLLLDTGHAVFSGIDPVNLIDKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRR
HHHHHHHHHCCHHHHCCCCHHHHHHHCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHC
GVFTVPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH
CEEECCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVKMSIQLGIAPINWCNDDDPNLGKDISFEQCINEMAMAGYSGTELGNKYPRDVRTLKT
CCEEEEEEECCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ALEQRGLQLSSSWFSTYFTEANAFEKTVSRFLEHLSFMRALGASYINVCECGHAIQGTDL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PILSAHIPQFTQEQWSLLIQGLHTLGRIAYDFNMKIVYHYHAGTGVFWEKDIDFLMTNTS
CHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEECCCCCEEECCCCEEEECCC
PKLVSLLLDTGHAVFSGIDPVNLIDKYGDRILYVHLKDIRPEVLRRVEMERLSFMDAVRR
HHHHHHHHHCCHHHHCCCCHHHHHHHCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHC
GVFTVPGDGAIDFIPIWAGLQKHRYNGWMIVEAEQDPEKAHPLEYAKKAYDYLHSFIH
CEEECCCCCCEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA