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The map label for this gene is bioD [H]

Identifier: 54294484

GI number: 54294484

Start: 1730557

End: 1731195

Strand: Reverse

Name: bioD [H]

Synonym: lpl1553

Alternate gene names: 54294484

Gene position: 1731195-1730557 (Counterclockwise)

Preceding gene: 54294485

Following gene: 54294483

Centisome position: 51.74

GC content: 37.09

Gene sequence:

>639_bases
ATGAAACGATATTTTGTTACGGGTACTGACACTGATTGTGGTAAGACATTTGTAACCAATCAATTAGTTAATTATTTTTC
AAGTTCGGCAGCGATAAAACCTATAGCAAGCGGATGTGAGTACAGTGAAAATCAATTAGTAAATTCTGATGCACTTTTAC
ACCAGCAACAGAATCATTTGCCTTTGGAAGTTGTTAATCCCTGGCGATTTAGATTGCCAGTTTCGCCGCACTTATCAGCA
AGGGCGGATGGTGCAAGTATTGATGTCCATAAAGTAGCTGATTATTGCCTTAATTTGCAACTGAATGATATTAAGAAATT
ATTTATCGAAGGAGCCGGGGGATTAATGGTTCCTCTGAATGAGCAGGACACTTGGCTTGATTTTTTAAAATTAACCAGGA
TCCCTGTTATTTTAGTTGTTGGTATGAAGTTGGGTTGCATCAACCACACTTTACTTACCCAGGAAGTGTTCGAAATAAAT
AAAATCAAATGTCAAGGATGGATTGCTAATTGCCTGGATCAGGACATGCTAATGCTTGATGAAAATATTAGTACCCTTGA
AGCCAAATTAAAATATCCTTTATTAGCCAGGACAAACTATGGCGGCAAGATTTCTGATATATGTTTAAGCTCCTTGTAA

Upstream 100 bases:

>100_bases
ATTACCCGAATTTTAAGTATGTCCTCTTCAACAGAGCAGCTCACATGCCTTTTCTGTCCCATACCGATTTATTTATTACA
ATGATGGATGAATTTATAAA

Downstream 100 bases:

>100_bases
TCGCAGTGAAATTTTATATCAAAACAGCACTATATACCTGATGTTATTGCTTGTTCTGCTTGCGCTATACCCATGGCAGC
AATTATAATGAAAAGTTAAA

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSENQLVNSDALLHQQQNHLPLEVVNPWRFRLPVSPHLSA
RADGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVFEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL

Sequences:

>Translated_212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSENQLVNSDALLHQQQNHLPLEVVNPWRFRLPVSPHLSA
RADGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVFEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL
>Mature_212_residues
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSENQLVNSDALLHQQQNHLPLEVVNPWRFRLPVSPHLSA
RADGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVFEIN
KIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=202, Percent_Identity=38.6138613861386, Blast_Score=133, Evalue=7e-33,
Organism=Escherichia coli, GI87081944, Length=206, Percent_Identity=32.5242718446602, Blast_Score=107, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324385, Length=156, Percent_Identity=31.4102564102564, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23716; Mature: 23716

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSENQLVNSDALLHQQQNHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEECCHHHHHHHCCCC
PLEVVNPWRFRLPVSPHLSARADGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLN
CEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECC
EQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVFEINKIKCQGWIANCLDQDMLMLD
CCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCHHHHHC
ENISTLEAKLKYPLLARTNYGGKISDICLSSL
CCHHHHHHHHCCCEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSENQLVNSDALLHQQQNHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEECCHHHHHHHCCCC
PLEVVNPWRFRLPVSPHLSARADGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLN
CEEEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECC
EQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVFEINKIKCQGWIANCLDQDMLMLD
CCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHEEECHHHHHHHCCHHHHHC
ENISTLEAKLKYPLLARTNYGGKISDICLSSL
CCHHHHHHHHCCCEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA