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The map label for this gene is 54294392

Identifier: 54294392

GI number: 54294392

Start: 1627783

End: 1628727

Strand: Reverse

Name: 54294392

Synonym: lpl1461

Alternate gene names: NA

Gene position: 1628727-1627783 (Counterclockwise)

Preceding gene: 54294395

Following gene: 54294391

Centisome position: 48.68

GC content: 39.58

Gene sequence:

>945_bases
ATGTCATCACTAAAATCCAGGGTTACCCTACTGCTTAATTGGTACACCAACCCTTATCATACCCCCATACTTGTGGCACA
ACAATTGGGATTTTATTCAGAAGAAGATATTAAGCTCGCCATTCTGGAGCCTGCAGATCCCAGTGATGTGACCGAAATTG
TTGGGCTGGGAACAGTAGATTTTGGTGTTAAAGCAATGATTCATACCGTTGCAGCCAAAGCAAAAGGTTATCCAGTTACT
TCCATAGGAACGCTTCTTGATGAGCCACCTACCGGACTTATTGCTTTAAAATCAAGTGGTATCAATTCTTTCCAGGATAT
TGTTGGGAAGCGAGTAGGCTATATCGGCGAATTCGGCAAAAAAATTATTGATGATTTGGCCAGCCTCGCAGGTATTGATC
CGACGAGCTACAAAACGGTCCGTATTGGCATGAATGTCACAGATGCCATTTATCGGGATGTTATCGACACTGGTATTGGT
TTTATTAATTTTCAAAAAGTTGAACTGGAGCATCTTTGCGGAGAAACTGTATTTTTACGAATCGATCAATTAGCTGGTTT
AGGCTGTTGTTGTTTCTGCTCAATACAATTTATTGTTCCTGAAACAACATTACAGCAACCTGAATTAGTCAAAGGATTTC
TCAGAGCAACACAGCGCGGCGCAGCCTACACGACAGAAAAACCTGAAGAAGCTTATGAGTTATTATGTCAGGCTAAACCA
CAGTTGCGGACTCCTTTATATCAAAAAATCTTTACAAGAACATTACCATTTTTTTCACGTACATTAATTAATGTTGGCAG
AGACTGGGATAAGGTTGGACGCTATACCAAGCATCTAAAAATTATTGATGAACATTTTGATATCTCGCAATGCTATACGA
ATCGTTTTTTGCCAGATACACCTTATTCTGATTTGAAACCAATCGCCTGTTGTCTTGAAAATTAA

Upstream 100 bases:

>100_bases
GCGTAAGGACGCCTTCAAAAAAACCATGGCCTTTTTAAGGCATGGTTCCCTTTTGCCATCTCCATAATATTTAAAAATAA
TAACATAAGGAGTTATGGCG

Downstream 100 bases:

>100_bases
TTATGCGAGCAGGCATTGTAGGTGCAGGGATCATGGGGCGTCTGCTGGCTTTTGCATTACATAATGCGGGCTGGCAGGTA
TCTCTTTTTGATCGCTCTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSSLKSRVTLLLNWYTNPYHTPILVAQQLGFYSEEDIKLAILEPADPSDVTEIVGLGTVDFGVKAMIHTVAAKAKGYPVT
SIGTLLDEPPTGLIALKSSGINSFQDIVGKRVGYIGEFGKKIIDDLASLAGIDPTSYKTVRIGMNVTDAIYRDVIDTGIG
FINFQKVELEHLCGETVFLRIDQLAGLGCCCFCSIQFIVPETTLQQPELVKGFLRATQRGAAYTTEKPEEAYELLCQAKP
QLRTPLYQKIFTRTLPFFSRTLINVGRDWDKVGRYTKHLKIIDEHFDISQCYTNRFLPDTPYSDLKPIACCLEN

Sequences:

>Translated_314_residues
MSSLKSRVTLLLNWYTNPYHTPILVAQQLGFYSEEDIKLAILEPADPSDVTEIVGLGTVDFGVKAMIHTVAAKAKGYPVT
SIGTLLDEPPTGLIALKSSGINSFQDIVGKRVGYIGEFGKKIIDDLASLAGIDPTSYKTVRIGMNVTDAIYRDVIDTGIG
FINFQKVELEHLCGETVFLRIDQLAGLGCCCFCSIQFIVPETTLQQPELVKGFLRATQRGAAYTTEKPEEAYELLCQAKP
QLRTPLYQKIFTRTLPFFSRTLINVGRDWDKVGRYTKHLKIIDEHFDISQCYTNRFLPDTPYSDLKPIACCLEN
>Mature_313_residues
SSLKSRVTLLLNWYTNPYHTPILVAQQLGFYSEEDIKLAILEPADPSDVTEIVGLGTVDFGVKAMIHTVAAKAKGYPVTS
IGTLLDEPPTGLIALKSSGINSFQDIVGKRVGYIGEFGKKIIDDLASLAGIDPTSYKTVRIGMNVTDAIYRDVIDTGIGF
INFQKVELEHLCGETVFLRIDQLAGLGCCCFCSIQFIVPETTLQQPELVKGFLRATQRGAAYTTEKPEEAYELLCQAKPQ
LRTPLYQKIFTRTLPFFSRTLINVGRDWDKVGRYTKHLKIIDEHFDISQCYTNRFLPDTPYSDLKPIACCLEN

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0715

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322616, Length=300, Percent_Identity=47.3333333333333, Blast_Score=274, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6321050, Length=300, Percent_Identity=47, Blast_Score=271, Evalue=7e-74,
Organism=Saccharomyces cerevisiae, GI6319957, Length=300, Percent_Identity=47, Blast_Score=271, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6323997, Length=300, Percent_Identity=46.6666666666667, Blast_Score=270, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 35004; Mature: 34873

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLKSRVTLLLNWYTNPYHTPILVAQQLGFYSEEDIKLAILEPADPSDVTEIVGLGTVD
CCCHHHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHH
FGVKAMIHTVAAKAKGYPVTSIGTLLDEPPTGLIALKSSGINSFQDIVGKRVGYIGEFGK
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
KIIDDLASLAGIDPTSYKTVRIGMNVTDAIYRDVIDTGIGFINFQKVELEHLCGETVFLR
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCHHEEE
IDQLAGLGCCCFCSIQFIVPETTLQQPELVKGFLRATQRGAAYTTEKPEEAYELLCQAKP
EHHHCCCCEEEHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
QLRTPLYQKIFTRTLPFFSRTLINVGRDWDKVGRYTKHLKIIDEHFDISQCYTNRFLPDT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
PYSDLKPIACCLEN
CCCHHHHHHHHCCC
>Mature Secondary Structure 
SSLKSRVTLLLNWYTNPYHTPILVAQQLGFYSEEDIKLAILEPADPSDVTEIVGLGTVD
CCHHHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCHH
FGVKAMIHTVAAKAKGYPVTSIGTLLDEPPTGLIALKSSGINSFQDIVGKRVGYIGEFGK
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
KIIDDLASLAGIDPTSYKTVRIGMNVTDAIYRDVIDTGIGFINFQKVELEHLCGETVFLR
HHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCHHEEE
IDQLAGLGCCCFCSIQFIVPETTLQQPELVKGFLRATQRGAAYTTEKPEEAYELLCQAKP
EHHHCCCCEEEHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
QLRTPLYQKIFTRTLPFFSRTLINVGRDWDKVGRYTKHLKIIDEHFDISQCYTNRFLPDT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
PYSDLKPIACCLEN
CCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]