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The map label for this gene is moeZ [H]

Identifier: 54294387

GI number: 54294387

Start: 1623140

End: 1624279

Strand: Reverse

Name: moeZ [H]

Synonym: lpl1456

Alternate gene names: 54294387

Gene position: 1624279-1623140 (Counterclockwise)

Preceding gene: 54294388

Following gene: 54294377

Centisome position: 48.55

GC content: 37.02

Gene sequence:

>1140_bases
ATGAATCACATAATGAATAAATCAACTTTGGCAATGAACGAATTAACCCGCTATTCTCAACAAATAAAGATGGAAGAAAT
TGGATTAGACGGACAGGAGAAACTTAAGAATTCTCGAGTATTATGCATTGGGCTTGGCGGTTTGGGTTCGCCTCTCTTAC
TTTACCTTGCTGCAGCAGGTGTAGGAGTGATAGGGATTGTCGATGATGACATCATTGAACTAAGTAATTTACATAGGCAG
ATTCTTTATAATCATGCCCATATTAATAAAAAAAAGGCTGTTACTGCAAAAAAGCAACTTCTGGCTATTAATCCCCTGAT
TCAAGTTGAATCTTACTCCAGTAGATTAACAGAGGAGAATGCGGCTGACTTAATTATGCAGTATGACATCATCGCAGATG
GAACCGATAATTTTTATACGCGATATTTGATTCACAGCATTTGCTTTGAGCTGGGAAAACCTTATGTGTATGCTGGCGCC
TCAGGTTTTCAAGGGTATTGCTCTATATTCCACGGTAAACAAGATCCCTGCCTCCATTGTATCTTCCCGGTTTCTGCAAG
CGATATCAATATGCTCAATTGCGAGGGAGCCGGGGTAATTGGTACTTTACCCGGGATGCTGGGTATTATTCAGGCAACAG
AAATAATCAAATGGATACTACAAATTGGCAATCCATTAAAAAAGCGTTTGCTTGCTATTAACTTGTTAACAATGACCTTT
AAGAACATCATTATTGCAAGAAATCCGGATTGTGAATTCTGCATTCAGAATCAGTCAATTAGACAATTAATTAATCCTGT
TAATTGTTCAACTCAAATTGAGCTATGCCATCATAGAATAACTTTTGATGAATTTTATCAATTACTCACGAATAATAAAA
ACATTCATCTAATTGATGTTCGTAGTACAAAGGAACATCAAATACAAAATATAGGAGGTATTGTGCTTCCTTTAGATGAG
CTGCCTCAACGCTTACATGAACTAAACCCTAATCAGCTTATTATTCTGTACTGCCAATCGGGAAAACGAAGCAAGATGGC
GTTAGATATACTTCTCAAGGCTGGCTTTGCTTCTGTTAAATATATAGAAAATGGTTTAAAGGGAGTAACTGCCAATTACA
ATAAAGGCATTCCCCAATAA

Upstream 100 bases:

>100_bases
GATGTCTTAAAAACAAAAATTGATGGTGTGTCAGTGATCTCTGCCATTACAAAAGCATCAGCACCTTTAGTTGCAGCCAA
ACAATTTTTAACTCAAATGA

Downstream 100 bases:

>100_bases
TTCACCCCTCCTAAAAAGGAAGCTGAGATTAAATAAGTTTATTTTTACCTTCGGCAATATTATTTAACAGATAAGCGAGT
CGACACCCAGCCAGAAGTAT

Product: hypothetical protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNHIMNKSTLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAGVGVIGIVDDDIIELSNLHRQ
ILYNHAHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAADLIMQYDIIADGTDNFYTRYLIHSICFELGKPYVYAGA
SGFQGYCSIFHGKQDPCLHCIFPVSASDINMLNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTF
KNIIIARNPDCEFCIQNQSIRQLINPVNCSTQIELCHHRITFDEFYQLLTNNKNIHLIDVRSTKEHQIQNIGGIVLPLDE
LPQRLHELNPNQLIILYCQSGKRSKMALDILLKAGFASVKYIENGLKGVTANYNKGIPQ

Sequences:

>Translated_379_residues
MNHIMNKSTLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAGVGVIGIVDDDIIELSNLHRQ
ILYNHAHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAADLIMQYDIIADGTDNFYTRYLIHSICFELGKPYVYAGA
SGFQGYCSIFHGKQDPCLHCIFPVSASDINMLNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTF
KNIIIARNPDCEFCIQNQSIRQLINPVNCSTQIELCHHRITFDEFYQLLTNNKNIHLIDVRSTKEHQIQNIGGIVLPLDE
LPQRLHELNPNQLIILYCQSGKRSKMALDILLKAGFASVKYIENGLKGVTANYNKGIPQ
>Mature_379_residues
MNHIMNKSTLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAGVGVIGIVDDDIIELSNLHRQ
ILYNHAHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAADLIMQYDIIADGTDNFYTRYLIHSICFELGKPYVYAGA
SGFQGYCSIFHGKQDPCLHCIFPVSASDINMLNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTF
KNIIIARNPDCEFCIQNQSIRQLINPVNCSTQIELCHHRITFDEFYQLLTNNKNIHLIDVRSTKEHQIQNIGGIVLPLDE
LPQRLHELNPNQLIILYCQSGKRSKMALDILLKAGFASVKYIENGLKGVTANYNKGIPQ

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=414, Percent_Identity=31.4009661835749, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI4885649, Length=149, Percent_Identity=28.1879194630872, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38045948, Length=164, Percent_Identity=32.3170731707317, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI23510338, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI23510340, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI150417996, Length=147, Percent_Identity=29.2517006802721, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38045942, Length=197, Percent_Identity=26.9035532994924, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI38045944, Length=197, Percent_Identity=26.9035532994924, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=36.4, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87082356, Length=242, Percent_Identity=38.0165289256198, Blast_Score=154, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17540406, Length=383, Percent_Identity=31.0704960835509, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI193203301, Length=150, Percent_Identity=30, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71984476, Length=180, Percent_Identity=29.4444444444444, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=403, Percent_Identity=31.0173697270471, Blast_Score=180, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6320598, Length=168, Percent_Identity=35.7142857142857, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322639, Length=174, Percent_Identity=30.4597701149425, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582879, Length=392, Percent_Identity=35.2040816326531, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=30.6666666666667, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573937, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129973, Length=204, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42315; Mature: 42315

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIMNKSTLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHC
VGVIGIVDDDIIELSNLHRQILYNHAHINKKKAVTAKKQLLAINPLIQVESYSSRLTEEN
CCEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCEEEEECHHHHHCCCH
AADLIMQYDIIADGTDNFYTRYLIHSICFELGKPYVYAGASGFQGYCSIFHGKQDPCLHC
HHHHEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCCEEE
IFPVSASDINMLNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTF
EEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KNIIIARNPDCEFCIQNQSIRQLINPVNCSTQIELCHHRITFDEFYQLLTNNKNIHLIDV
HCEEEEECCCCCEEECCHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEE
RSTKEHQIQNIGGIVLPLDELPQRLHELNPNQLIILYCQSGKRSKMALDILLKAGFASVK
CCCCHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHH
YIENGLKGVTANYNKGIPQ
HHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNHIMNKSTLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHC
VGVIGIVDDDIIELSNLHRQILYNHAHINKKKAVTAKKQLLAINPLIQVESYSSRLTEEN
CCEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCEEEEECHHHHHCCCH
AADLIMQYDIIADGTDNFYTRYLIHSICFELGKPYVYAGASGFQGYCSIFHGKQDPCLHC
HHHHEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCCEEE
IFPVSASDINMLNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTF
EEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KNIIIARNPDCEFCIQNQSIRQLINPVNCSTQIELCHHRITFDEFYQLLTNNKNIHLIDV
HCEEEEECCCCCEEECCHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEE
RSTKEHQIQNIGGIVLPLDELPQRLHELNPNQLIILYCQSGKRSKMALDILLKAGFASVK
CCCCHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHH
YIENGLKGVTANYNKGIPQ
HHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]