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The map label for this gene is yybO [H]

Identifier: 54294290

GI number: 54294290

Start: 1510024

End: 1511316

Strand: Direct

Name: yybO [H]

Synonym: lpl1355

Alternate gene names: 54294290

Gene position: 1510024-1511316 (Clockwise)

Preceding gene: 54294289

Following gene: 54294292

Centisome position: 45.13

GC content: 40.99

Gene sequence:

>1293_bases
TTGACCGCACATTACAACGTCGCTTCAAACAGTGGAGCAAGAAATACACTTGCAACGTCTTATTTTATTTTTTTTCTAGC
CGCTTCATTTTATTTGTATGAATTCATACTACAAGTAGCACCAAGCGTTATGGCAGAGTCGATGATGAAAACTTTTGGGG
TGACGGGTCAAGGCTTTGGTGTCATTTCAGCTTTTTATTTTTATGCTTATGCCCCTACACAATTGCCAGCAGGAGTATTA
TACGATAGATATGGACCACGCAAGTTAATGACTTTTGCAATCATTTTGTGTGCATTTGGTTCTGCCTTTTTTGCTTCCAC
TGACAGTGTATTTACAGCTTGCATAGGCCGATTTTTGATCGGAATAGGCTCTGCGTTTTCTTTTATCGGGGTTTTGGTCC
TTATTTCACGCTGGTTTCCACCTTATTATTTTGCAATTCTAGCAGGGGTAGCGCAGTTGATGAGTTCAGTCGGCGCTATG
TTTGGTGAAATGCCGTTGGCAGCTTTAATCGATCTGGTTGGATGGAGAAGTGCGAGTTTTATTTTAGCGGGCGTTGGATT
TCTCCTGGCTATTTTATTTTGGGTATTTATTCGAGATTATCCTCATCAGCAAAATCAGACAATCCCTGATCATTATTTAA
GAGATGAATGGAAACGCTTAATTGCTGTCTGTAAACATGCTTATACATGGATCATAGGTGGTTATGCTTTTGCAATTTGG
ACTCCTATTGCAGTATTTGCTGCACTTTGGGGAGTTCCTTTTTTACAGGAAAAATTTCAAGTAAGCGTAGTGGCTGCCTC
AGGCTTATGCAGTATGATTTGGCTGGGCATTGGTGTTGGTAGCCCCTTGTTAGGTTGGTTGAGTGATAAATTGGAGAGTC
GCCGTATTGCATTGATTATTAGTGCGGTTTTAGGACTGATTGCAACTCTGATTATCCTTTATTGGTCTGAGTTATCTTAT
AATTGGGCTTATGTTGTCTTGTTCGTTTTAGGATTAGGCGCTGGAGGACAGACGGTAAGTTTTGCAGTAGTTAAAGAAAA
TAATACCCCGGAGTTAGTTGGCACAGCATCTGGTTTTAATAATTTGTCTGTATTAATTGGCGGGGCCATTTTTCAGCCCC
TCGTTGGTTATATCTTGCAACAGACAGGATCATGGCGAATTGTCAATGGTGCTCATGTATACAGTATATCGAGTTACCAG
ACTGCGTTGCTTGTTATGCCAGTATGCTTCCTGGCCAGTTTGCTTATTGCCACTTTTTTGCTTAAGGAATCGCATCCTGC
GAGCAGAGATTAA

Upstream 100 bases:

>100_bases
ATTGCAATTTTAGGTGCAGTGTATCCTATAATAAAATCATATTGACAAACTAAAGAATCATAAGGTTTAATTTCATAATA
ATTAACAGAGTGATTTTAAA

Downstream 100 bases:

>100_bases
TAACAGATTTATCAATTCAATTTTGCGTTATTGACTAAAACAAAGTAATCAGTTTATGTCAATGTGGCTTGTTCTCATGA
GTTAGCCACATTACTATTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFGVISAFYFYAYAPTQLPAGVL
YDRYGPRKLMTFAIILCAFGSAFFASTDSVFTACIGRFLIGIGSAFSFIGVLVLISRWFPPYYFAILAGVAQLMSSVGAM
FGEMPLAALIDLVGWRSASFILAGVGFLLAILFWVFIRDYPHQQNQTIPDHYLRDEWKRLIAVCKHAYTWIIGGYAFAIW
TPIAVFAALWGVPFLQEKFQVSVVAASGLCSMIWLGIGVGSPLLGWLSDKLESRRIALIISAVLGLIATLIILYWSELSY
NWAYVVLFVLGLGAGGQTVSFAVVKENNTPELVGTASGFNNLSVLIGGAIFQPLVGYILQQTGSWRIVNGAHVYSISSYQ
TALLVMPVCFLASLLIATFLLKESHPASRD

Sequences:

>Translated_430_residues
MTAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFGVISAFYFYAYAPTQLPAGVL
YDRYGPRKLMTFAIILCAFGSAFFASTDSVFTACIGRFLIGIGSAFSFIGVLVLISRWFPPYYFAILAGVAQLMSSVGAM
FGEMPLAALIDLVGWRSASFILAGVGFLLAILFWVFIRDYPHQQNQTIPDHYLRDEWKRLIAVCKHAYTWIIGGYAFAIW
TPIAVFAALWGVPFLQEKFQVSVVAASGLCSMIWLGIGVGSPLLGWLSDKLESRRIALIISAVLGLIATLIILYWSELSY
NWAYVVLFVLGLGAGGQTVSFAVVKENNTPELVGTASGFNNLSVLIGGAIFQPLVGYILQQTGSWRIVNGAHVYSISSYQ
TALLVMPVCFLASLLIATFLLKESHPASRD
>Mature_429_residues
TAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFGVISAFYFYAYAPTQLPAGVLY
DRYGPRKLMTFAIILCAFGSAFFASTDSVFTACIGRFLIGIGSAFSFIGVLVLISRWFPPYYFAILAGVAQLMSSVGAMF
GEMPLAALIDLVGWRSASFILAGVGFLLAILFWVFIRDYPHQQNQTIPDHYLRDEWKRLIAVCKHAYTWIIGGYAFAIWT
PIAVFAALWGVPFLQEKFQVSVVAASGLCSMIWLGIGVGSPLLGWLSDKLESRRIALIISAVLGLIATLIILYWSELSYN
WAYVVLFVLGLGAGGQTVSFAVVKENNTPELVGTASGFNNLSVLIGGAIFQPLVGYILQQTGSWRIVNGAHVYSISSYQT
ALLVMPVCFLASLLIATFLLKESHPASRD

Specific function: Uptake Of D-Glucarate. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI1789152, Length=402, Percent_Identity=24.1293532338308, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561500, Length=276, Percent_Identity=24.6376811594203, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534562, Length=276, Percent_Identity=24.6376811594203, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46999; Mature: 46867

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCC
>Mature Secondary Structure 
TAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFG
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH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HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]