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The map label for this gene is cysS [H]

Identifier: 54294205

GI number: 54294205

Start: 1412906

End: 1414276

Strand: Direct

Name: cysS [H]

Synonym: lpl1270

Alternate gene names: 54294205

Gene position: 1412906-1414276 (Clockwise)

Preceding gene: 54294204

Following gene: 54294206

Centisome position: 42.23

GC content: 40.34

Gene sequence:

>1371_bases
ATGTTACATTTATATAATTCTTTGACCAGAAAAAAAGAACCATTTGTTTCCTTAAGGCCCGGAAAGATAGGTATGTATGT
TTGCGGAATTACTGTTTATGACCACTGCCACTTAGGGCATGCCCGTTCAATGGTTGCCTTTGATGTAATGGTTCGTTATC
TGCGCTCACAAGGATTCGATGTAACTTATGTACGCAATATAACTGATATAGATGATAAAATCATTGCAAGAGCCTCGGAG
AGAGATGTATCTATTGATGAATTGACCGCACAATATATTGATGCAATGAATAATGATACTCATGCATTAAATATTTTGCC
ACCTGACCATGAGCCAAGGGCAACCGGGCATATTGAAACAATCATTCGCTTGATTCAACGTTTGCTTGAAAAAGGTAACG
CGTATGTCAGTGAGAATGGCGATGTGTGCTATGAAGTAGATACCTTTCCCGAATATGGGAAATTATCGCATAAGGATATT
GAAGGCTTGGTTTCGGGTTCTCGCGTAGAGATTGTAAAAGAGAAACGTTCCCCGCTTGATTTTGTGCTATGGAAAAAAGC
AAAACCAGGTGAACCCAGTTGGCCTTCACCGTGGGGGGAAGGGCGGCCTGGATGGCACATTGAGTGTTCAGCTATGGCTA
TGCATGAATTAGGTGAACAATTTGATATTCATGGAGGTGGATTGGATTTGCAATTCCCACATCATGAAAATGAAATTGCT
CAAAGTGAAGCGGCTACTGGTAAACCTTTTGCTAATTATTGGCTGCATGTCGGAATGTTGCAGGTTAATGGCGAAAAAAT
GGCAAAATCAATAGGGAACTTTTACACTATTGCCGATGTTTTAAAAGAGCATCATCCGGAAGTCATCCGCTATTTTCTAT
TAAGTAGTCATTATCGCAGTCCTTTGAATTATTCAGAAGAAAATTTGTTAAATGCCAAAAAAGCCCTTATCAGGCTTTAT
CAAGCGGTTAAAGATGTTCCGCCACAAACTGCAGATAGCAAACTGGATGAGTATTGGCAAGAGCAATTTAATCAGGCAAT
GAATGATGATTTCAATACTCCTGTTGCATTATCGGTTCTTTTCCAATTGGCTCATGAGGTAAACAAAAGTAATTCACCTG
CATTGGCTCATACCCTGAAAAACCTTGCTGGTATTCTTGGATTTTTACAAAAAGATCCCGAATCATTCCTGCAATCCGGC
TTGGCAGAGGAAGAAAAATTGGTTATAGAACAACTCATTGCAGAACGTCTTAAGGCACGAGCAGAACGCAATTGGACAAA
GGCAGATCAGATTAGAGCTGATTTATTGAGCAAAGGCATAGAGCTGGAAGATGGTGCAACAGGAACAACATGGCGGAGGA
TTGCTGAATAA

Upstream 100 bases:

>100_bases
ATATTATTGCGTCAATTCAGTGGCTGAGGGCTGTGTTCAAGCCTTTCATCGGGTAGTGGATTTGAAGGACACTTGGGGTA
AAGTGAGTTGAGAGGCAGAC

Downstream 100 bases:

>100_bases
TTGTTCCTTCTATGCGCTTCTCTTGAAGCAGAATGGACTTCTATCTCATACTTAATATAGACTGCAATTACCTTTTCAGA
AATTTTAAATCAGGTATATT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLHLYNSLTRKKEPFVSLRPGKIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASE
RDVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDI
EGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLY
QAVKDVPPQTADSKLDEYWQEQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSG
LAEEEKLVIEQLIAERLKARAERNWTKADQIRADLLSKGIELEDGATGTTWRRIAE

Sequences:

>Translated_456_residues
MLHLYNSLTRKKEPFVSLRPGKIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASE
RDVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDI
EGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLY
QAVKDVPPQTADSKLDEYWQEQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSG
LAEEEKLVIEQLIAERLKARAERNWTKADQIRADLLSKGIELEDGATGTTWRRIAE
>Mature_456_residues
MLHLYNSLTRKKEPFVSLRPGKIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASE
RDVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDI
EGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLY
QAVKDVPPQTADSKLDEYWQEQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSG
LAEEEKLVIEQLIAERLKARAERNWTKADQIRADLLSKGIELEDGATGTTWRRIAE

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=508, Percent_Identity=37.7952755905512, Blast_Score=279, Evalue=4e-75,
Organism=Homo sapiens, GI10835051, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI21269877, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI303304987, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI62240992, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=55.531453362256, Blast_Score=513, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17509797, Length=269, Percent_Identity=39.7769516728625, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17509795, Length=269, Percent_Identity=39.7769516728625, Blast_Score=191, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6324082, Length=339, Percent_Identity=35.3982300884956, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19922218, Length=501, Percent_Identity=34.1317365269461, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI19922364, Length=277, Percent_Identity=40.4332129963899, Blast_Score=197, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51673; Mature: 51673

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLYNSLTRKKEPFVSLRPGKIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFD
CCCHHHHHHHCCCCCEEECCCCEEEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
VTYVRNITDIDDKIIARASERDVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIET
EEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
IIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDIEGLVSGSRVEIVKEKRSPLD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCC
FVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCHHEECCCCCEEEECCCCHHHHH
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRS
HHHCCCCCCHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
PLNYSEENLLNAKKALIRLYQAVKDVPPQTADSKLDEYWQEQFNQAMNDDFNTPVALSVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSGLAEEEKLVIEQLIAERLKAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AERNWTKADQIRADLLSKGIELEDGATGTTWRRIAE
HHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MLHLYNSLTRKKEPFVSLRPGKIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFD
CCCHHHHHHHCCCCCEEECCCCEEEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
VTYVRNITDIDDKIIARASERDVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIET
EEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
IIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDIEGLVSGSRVEIVKEKRSPLD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCC
FVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCHHEECCCCCEEEECCCCHHHHH
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRS
HHHCCCCCCHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
PLNYSEENLLNAKKALIRLYQAVKDVPPQTADSKLDEYWQEQFNQAMNDDFNTPVALSVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSGLAEEEKLVIEQLIAERLKAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AERNWTKADQIRADLLSKGIELEDGATGTTWRRIAE
HHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA