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The map label for this gene is pntB [H]

Identifier: 54293851

GI number: 54293851

Start: 1018865

End: 1020262

Strand: Reverse

Name: pntB [H]

Synonym: lpl0907

Alternate gene names: 54293851

Gene position: 1020262-1018865 (Counterclockwise)

Preceding gene: 54293852

Following gene: 54293850

Centisome position: 30.49

GC content: 43.49

Gene sequence:

>1398_bases
ATGAATTCAATAGTTCCACTGTTTTATTTATTGGCAGCCATTTGCTTTATATTGGCTTTAAAAGGACTGGCCAGTCCCTC
AACTTCAAGAAGGGGGAACCTTCTAGGTATTATGGGTATGATCCTGGCAGTGGGCTCCACCCTGATGATGCCCACTACCT
ACCATCATATTCTTTTAATCGCCTTAATAGCAGGCGGCGGAATAATAGGAACTATTATTGCTTTGAAGATCAACATGACG
GCCATACCACAACTGGTTGCTGCTTTTCATTCTTTAGTAGGCATGGCAGCAGTTCTGGTGGCCTATTGTGCCTTTTTATC
CCCCGCGTCCTTTCAAATCGGTACACCTGGTGCTATTGCTACCGCAAGTCTAATTGAAATGAGCCTGGGATTAATCATCG
GAGCCATTACCTTTTCTGGTTCAGTTATTGCCTTTTTAAAATTGCAAGGACTCATATCAGGTATCCCCATTCGATTTTAT
GCTCAAAACTATGTCAACTTACTAATAGGACTAACAATCCTGGTGTTACTCATTTTATTTGTAGCCAATCAAAACCTGTT
TCTCTTTAACCTGCTCGCGGGATTAGCTTTTGTCATTGGGGTTTTACTGATTATTCCTATTGGCGGAGCTGATATGCCCG
TCGTTATTTCCATGCTGAACTCCTACTCAGGTTGGGCCGCAGCAGGAATAGGTTTCACTCTGAGTAATCATCTGTTAGTT
ATCACAGGTGCATTAGTTGGCGCCAGCGGGGCAATTTTAAGTTATATCATGTGCGTTGGCATGAATCGCTCTATCTTTAA
TGTTATTTTTGGTGGAATAAACAGTTCTGGGAACACGAAACAAGCCCATTCCGGCAATGAGCTACGCAATGTAAGACAGG
CCAACGGCGAAGACGCTGCCTTCCTATTAAGTAATGCCAAGGATGTCATCATTGTTCCTGGATATGGAATGGCAGTGGCA
CATGCTCAACATGCGGTGAAAGAGCTTGTTGATGCTCTGGAATCTCGTTCTATTCGTGTTCGTTTTGCAATACACCCTGT
TGCCGGACGCATGCCCGGCCATATGAACGTATTACTTGCTGAGGCCAATATCCCCTATGACAGAGTCTTTGAGCAAAGTG
AAATTAACAGAGATTTTGCTACCTGTGACGTTGCTTACGTGATTGGAGCTAACGATATCACCAACCCTGCAGCTAAAACC
GATCCTGCCTCCCCCATTTATGGGATGCCTGTCCTGGAGGTTGAAAAAGCTAAAACGGTCTTATTTGTCAAACGCAGTTT
ATCTCCTGGCTATGCCGGTGTGGAAAACAATTTATTTTTTCACGACAATACCTACATGCTTTTCGGAGATGCCAAAGTAA
TGACTGAATCAATAGCTAAGGCTTTGGGAGAAATATAA

Upstream 100 bases:

>100_bases
CCATATTTATTACTTCAATCAATATTTTTGGTGGCTTTGTAGTAACTCAACGCATGCTTCGCATGTATAAAAAATAATGA
TTTAAAGGACGGAATCAGTA

Downstream 100 bases:

>100_bases
CCCTTTCAAAATTATAGCAATAATCTCTGACGGGGTGGGTACCCGGTTCAATCGACGCAAATGCCTTTTAATTTGCCAAC
AAAGCAAAATAAATGTATCT

Product: NAD(P) transhydrogenase subunit beta (pyridine nucleotide transhydrogenase subunit beta)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNSIVPLFYLLAAICFILALKGLASPSTSRRGNLLGIMGMILAVGSTLMMPTTYHHILLIALIAGGGIIGTIIALKINMT
AIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFY
AQNYVNLLIGLTILVLLILFVANQNLFLFNLLAGLAFVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLSNHLLV
ITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQAHSGNELRNVRQANGEDAAFLLSNAKDVIIVPGYGMAVA
HAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKT
DPASPIYGMPVLEVEKAKTVLFVKRSLSPGYAGVENNLFFHDNTYMLFGDAKVMTESIAKALGEI

Sequences:

>Translated_465_residues
MNSIVPLFYLLAAICFILALKGLASPSTSRRGNLLGIMGMILAVGSTLMMPTTYHHILLIALIAGGGIIGTIIALKINMT
AIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFY
AQNYVNLLIGLTILVLLILFVANQNLFLFNLLAGLAFVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLSNHLLV
ITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQAHSGNELRNVRQANGEDAAFLLSNAKDVIIVPGYGMAVA
HAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKT
DPASPIYGMPVLEVEKAKTVLFVKRSLSPGYAGVENNLFFHDNTYMLFGDAKVMTESIAKALGEI
>Mature_465_residues
MNSIVPLFYLLAAICFILALKGLASPSTSRRGNLLGIMGMILAVGSTLMMPTTYHHILLIALIAGGGIIGTIIALKINMT
AIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIATASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFY
AQNYVNLLIGLTILVLLILFVANQNLFLFNLLAGLAFVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLSNHLLV
ITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQAHSGNELRNVRQANGEDAAFLLSNAKDVIIVPGYGMAVA
HAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLAEANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKT
DPASPIYGMPVLEVEKAKTVLFVKRSLSPGYAGVENNLFFHDNTYMLFGDAKVMTESIAKALGEI

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=471, Percent_Identity=44.5859872611465, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI122939153, Length=471, Percent_Identity=44.5859872611465, Blast_Score=357, Evalue=2e-98,
Organism=Escherichia coli, GI1787886, Length=459, Percent_Identity=52.5054466230937, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17550456, Length=460, Percent_Identity=46.7391304347826, Blast_Score=363, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49097; Mature: 49097

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIVPLFYLLAAICFILALKGLASPSTSRRGNLLGIMGMILAVGSTLMMPTTYHHILLI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHHHHH
ALIAGGGIIGTIIALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIA
HHHHCCCHHEEHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHH
TASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFYAQNYVNLLIGLTILVLLILF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VANQNLFLFNLLAGLAFVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLSNHLLV
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCHHHCCCEEE
ITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQAHSGNELRNVRQANGEDAA
EEEHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCE
FLLSNAKDVIIVPGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLA
EEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEE
EANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKTDPASPIYGMPVLEVEKAKTV
ECCCCHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHCCCEE
LFVKRSLSPGYAGVENNLFFHDNTYMLFGDAKVMTESIAKALGEI
EEEEECCCCCCCCCCCCEEEECCEEEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSIVPLFYLLAAICFILALKGLASPSTSRRGNLLGIMGMILAVGSTLMMPTTYHHILLI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHHHHH
ALIAGGGIIGTIIALKINMTAIPQLVAAFHSLVGMAAVLVAYCAFLSPASFQIGTPGAIA
HHHHCCCHHEEHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHH
TASLIEMSLGLIIGAITFSGSVIAFLKLQGLISGIPIRFYAQNYVNLLIGLTILVLLILF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VANQNLFLFNLLAGLAFVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLSNHLLV
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCHHHCCCEEE
ITGALVGASGAILSYIMCVGMNRSIFNVIFGGINSSGNTKQAHSGNELRNVRQANGEDAA
EEEHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCE
FLLSNAKDVIIVPGYGMAVAHAQHAVKELVDALESRSIRVRFAIHPVAGRMPGHMNVLLA
EEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEE
EANIPYDRVFEQSEINRDFATCDVAYVIGANDITNPAAKTDPASPIYGMPVLEVEKAKTV
ECCCCHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHCCCEE
LFVKRSLSPGYAGVENNLFFHDNTYMLFGDAKVMTESIAKALGEI
EEEEECCCCCCCCCCCCEEEECCEEEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]