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The map label for this gene is paaF [C]

Identifier: 54293846

GI number: 54293846

Start: 1012760

End: 1013818

Strand: Direct

Name: paaF [C]

Synonym: lpl0902

Alternate gene names: 54293846

Gene position: 1012760-1013818 (Clockwise)

Preceding gene: 54293845

Following gene: 54293849

Centisome position: 30.27

GC content: 39.57

Gene sequence:

>1059_bases
ATGACTGAAGAGGTGCTGTTTTCTCAGGAAGGTCAATTGGGATTCATTACTTTAAATCGACCAAAGGCTTTAAATGCTTT
AACTTTAACCATGATCATGGCGTTGCAAAAGCAATTGTCAATTTGGAAAGAAGATTATTCTATTAAAGCAGTCGTCGTGC
AAGCTGTTCCGGGCAATGCTTTTTGCGCAGGTGGTGATATTCGTTGGCTATATAATGCGGGTCGTAGTAAAGACTCTGAG
CAGATGCAGTTCTTTTGGCATGAGTACAGATTAAATCATTTTATTCATCATTTTGGTAAACCTTATATTTCTTTGCTGGA
TGGGATTACTATGGGAGGAGGGGTTGGTATTTCCTTACATGGAAGCCACCCTGTTGCCAGTGAGCGTTTTGTATTTGCAA
TGCCAGAAACAGGGATTGGTTTTTTTCCTGATATTGGTGCCAGCTATTTATTAAACAGATGCCCAGGGTTTTTAGGAGTC
TATTTGGGGTTAACCGGAAATAAATTGGGTCCTCATGATGCAAGGAAGGCAGGATTAGTGAAACAGATTGTCTTTGCAGA
GCAAATGCAGTCAATGATTGAGGCATTAAAGAGAGAAGATTTATCAGAAGATGCTTTCAATCGTGTCGATCAATGCATTT
CTTCTTTTGCAAGTGATGCCGTGCCCACCGAGGCAAGTCAAATCAAACCTTTAATCGATGTTTGTTTCTCCAAACCTAGT
GTTGAACTAATAAGAGAATCGTTACAAAGCACAGAAGGTGTGTGGGCTCTTGGAGTGGACAATACTTTACTGCAAAAATC
GCCTCTGAGCCTTAAGATAACCCTTGCACAAATCCAAAAAGCCAAGGGCTTATCTTTAGCAGAATGTTTAAAAATGGATT
TCGATCTGGCCAGTCATTTTATGAAAGGTAGTGATTTTTATGAAGGAGTTCGCTCTTTATTGATTAATAAAGATAAAAAT
CCTCAATGGAGACCGTCCAGTTTGGAGTTGGTCACTGATGCCATGGTAGTGAGTTATTTTGAAAGCTCATCTTCCGGATT
GGAATTAATGATACTTTAG

Upstream 100 bases:

>100_bases
AAGCAATTCATTTTGCAAAAGTTTGTGCCACTGAAGATAAGAAGGAAGGAGTAGCTGCGTTTCTAGACAAGAGAACTGCA
GATTTTAAAGGGGTTTAATT

Downstream 100 bases:

>100_bases
TTTTCTGGATTTTGATTGGGGGAATAATAGATTTCCTGTATGAATACTTCCTTATGGTTGAAAAGCAGTTTGAAATATTA
TCTGCTTGCTGTCATAAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDYSIKAVVVQAVPGNAFCAGGDIRWLYNAGRSKDSE
QMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLHGSHPVASERFVFAMPETGIGFFPDIGASYLLNRCPGFLGV
YLGLTGNKLGPHDARKAGLVKQIVFAEQMQSMIEALKREDLSEDAFNRVDQCISSFASDAVPTEASQIKPLIDVCFSKPS
VELIRESLQSTEGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHFMKGSDFYEGVRSLLINKDKN
PQWRPSSLELVTDAMVVSYFESSSSGLELMIL

Sequences:

>Translated_352_residues
MTEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDYSIKAVVVQAVPGNAFCAGGDIRWLYNAGRSKDSE
QMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLHGSHPVASERFVFAMPETGIGFFPDIGASYLLNRCPGFLGV
YLGLTGNKLGPHDARKAGLVKQIVFAEQMQSMIEALKREDLSEDAFNRVDQCISSFASDAVPTEASQIKPLIDVCFSKPS
VELIRESLQSTEGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHFMKGSDFYEGVRSLLINKDKN
PQWRPSSLELVTDAMVVSYFESSSSGLELMIL
>Mature_351_residues
TEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDYSIKAVVVQAVPGNAFCAGGDIRWLYNAGRSKDSEQ
MQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLHGSHPVASERFVFAMPETGIGFFPDIGASYLLNRCPGFLGVY
LGLTGNKLGPHDARKAGLVKQIVFAEQMQSMIEALKREDLSEDAFNRVDQCISSFASDAVPTEASQIKPLIDVCFSKPSV
ELIRESLQSTEGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHFMKGSDFYEGVRSLLINKDKNP
QWRPSSLELVTDAMVVSYFESSSSGLELMIL

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=348, Percent_Identity=40.8045977011494, Blast_Score=258, Evalue=5e-69,
Organism=Homo sapiens, GI37594469, Length=304, Percent_Identity=40.1315789473684, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI194097323, Length=180, Percent_Identity=34.4444444444444, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1787659, Length=186, Percent_Identity=30.1075268817204, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI221142681, Length=185, Percent_Identity=24.8648648648649, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=347, Percent_Identity=39.7694524495677, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI25144157, Length=347, Percent_Identity=39.7694524495677, Blast_Score=241, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI25145438, Length=186, Percent_Identity=30.1075268817204, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=183, Percent_Identity=30.0546448087432, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=188, Percent_Identity=30.3191489361702, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=348, Percent_Identity=31.6091954022989, Blast_Score=152, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571730, Length=353, Percent_Identity=40.7932011331445, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI28571729, Length=353, Percent_Identity=40.7932011331445, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI20129971, Length=192, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24653477, Length=192, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 38956; Mature: 38825

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDYSIKAVVVQAVPGNA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
FCAGGDIRWLYNAGRSKDSEQMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLH
EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEE
GSHPVASERFVFAMPETGIGFFPDIGASYLLNRCPGFLGVYLGLTGNKLGPHDARKAGLV
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHH
KQIVFAEQMQSMIEALKREDLSEDAFNRVDQCISSFASDAVPTEASQIKPLIDVCFSKPS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
VELIRESLQSTEGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHF
HHHHHHHHHHCCCEEEEECCCHHHCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHH
MKGSDFYEGVRSLLINKDKNPQWRPSSLELVTDAMVVSYFESSSSGLELMIL
HCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
TEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDYSIKAVVVQAVPGNA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
FCAGGDIRWLYNAGRSKDSEQMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLH
EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEE
GSHPVASERFVFAMPETGIGFFPDIGASYLLNRCPGFLGVYLGLTGNKLGPHDARKAGLV
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHH
KQIVFAEQMQSMIEALKREDLSEDAFNRVDQCISSFASDAVPTEASQIKPLIDVCFSKPS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
VELIRESLQSTEGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHF
HHHHHHHHHHCCCEEEEECCCHHHCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHH
MKGSDFYEGVRSLLINKDKNPQWRPSSLELVTDAMVVSYFESSSSGLELMIL
HCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA