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The map label for this gene is dinP [H]

Identifier: 54293545

GI number: 54293545

Start: 645949

End: 647016

Strand: Reverse

Name: dinP [H]

Synonym: lpl0597

Alternate gene names: 54293545

Gene position: 647016-645949 (Counterclockwise)

Preceding gene: 54293546

Following gene: 54293544

Centisome position: 19.34

GC content: 40.73

Gene sequence:

>1068_bases
ATGAATCCGATAAGAAAAATTATCCATATTGATATGGACTGTTTTTATGCGGCAATTGAAATGCGTGATTTCCCTGAGCT
GGCAAATAAACCTATCGCTGTAGGCGGGGATGCAAAACATCGTGGAGTCATAGCAACCTGTAATTATGCTGCCCGCCAAT
TTGGCATACGCTCTGCAATGCCAACAGCCCATGCGCTTAAACTTTGCCGAGAATTAATCTTACGGCCAGTCCGTATGGAT
GTATACCAAAAGGAAAGTCAATATATTAGATCCCTATTAACAGAATACACAGACCTCATTGAACCTTTATCATTAGATGA
AGCCTATCTGGATGTCACTGAATCCACACAATGCCAGGGAAGCGCCACCTGGATTGCTGAAGAAATACGCGCCCGAATTT
ATCAAACAAGGCAACTCACTGCGAGTGCAGGCATTGCGCCAAATAAGAGTCTCGCAAAAATAGCCAGTGATTGGCATAAA
CCGAATGGGCAAATGGTTATTAGACCTGAGGACGTTAGCGCATTTGTTCTTGATTTACCAGTACGCAAGTTATTTGGTGT
AGGGCCCAAGATGGAGGAAAAATTGGGGGCGCTCAACATTAAAACCTGTGCTGATTTGCAGCGATATTCCATTGAATATT
TATTACAAAAATTTGGCACCATGGGTCAAAGACTTTATGAATTAGCGCGAGGCATTGATAATCGCCCCGTCAATCCTGAG
CGTATTCGAAAATCCATCAGCGTTGAAGAAACCTATCCAAAAGACTTGCCAAATAGTGAAGCTTGCCTGGCAGTCTTGCC
AGATCTTATGGCGCGCCTTGAAGCAAGAATACAACGTGCAGGTAAAATTTCTGGCATTCACAATTTATTTGTAAAATTGA
AGTTTAATGACTTTCAGCAAACAACTATTGAACGAGTTATGGATAAAATTGATTTAATCGTTTTACGTCAATTGATACAA
GAAGGTTTTGCCAGAAGAGGCATGCCAGTACGATTATTAGGTATAGGAATTAAATTGAAACAAGAAAATACGTATCAAAG
CGTACAATTGCCATTACTTGACTTATAA

Upstream 100 bases:

>100_bases
AAGTAAAAAATAGTTATTCTGTAGACTAAACTTTACAGCTTCAAGAAAATCAACTAAGACCTAATATGAAATCTCTGTTA
TTGCAATCTGTGGTTGAAAA

Downstream 100 bases:

>100_bases
CAAGTATCTAAACAGTTGATATCAGATTCTTTCCCAAACTTGCCATAATTATCAGAACTTAATACATAACTCTCTTTTTT
ATGCGACACCCTGCAATAGT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKHRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLGALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKIDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL

Sequences:

>Translated_355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKHRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLGALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKIDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
>Mature_355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKHRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLGALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKIDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=328, Percent_Identity=32.6219512195122, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI7706681, Length=329, Percent_Identity=31.9148936170213, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI154350220, Length=315, Percent_Identity=31.4285714285714, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=49.0740740740741, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI5729982, Length=325, Percent_Identity=28.6153846153846, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786425, Length=340, Percent_Identity=52.3529411764706, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1787432, Length=229, Percent_Identity=29.6943231441048, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=398, Percent_Identity=31.9095477386935, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=284, Percent_Identity=27.8169014084507, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=343, Percent_Identity=29.4460641399417, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324921, Length=272, Percent_Identity=29.0441176470588, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=30.3405572755418, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24668444, Length=125, Percent_Identity=36.8, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40287; Mature: 40287

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKHRGVIATCNYAARQFGIRSAM
CCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCEEEECCHHHHHHHHHHCC
PTAHALKLCRELILRPVRMDVYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
SATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHKPNGQMVIRPEDVSAFVLDLP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VRKLFGVGPKMEEKLGALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
HHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHH
TTIERVMDKIDLIVLRQLIQEGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKHRGVIATCNYAARQFGIRSAM
CCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCEEEECCHHHHHHHHHHCC
PTAHALKLCRELILRPVRMDVYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
SATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHKPNGQMVIRPEDVSAFVLDLP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VRKLFGVGPKMEEKLGALNIKTCADLQRYSIEYLLQKFGTMGQRLYELARGIDNRPVNPE
HHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RIRKSISVEETYPKDLPNSEACLAVLPDLMARLEARIQRAGKISGIHNLFVKLKFNDFQQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHH
TTIERVMDKIDLIVLRQLIQEGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA